NRF2 and the Hallmarks of Cancer MR de la Vega, E Chapman, DD Zhang Cancer cell 34 (1), 21-43, 2018 | 1077 | 2018 |
p62 links autophagy and Nrf2 signaling T Jiang, B Harder, MR De La Vega, PK Wong, E Chapman, DD Zhang Free Radical Biology and Medicine 88, 199-204, 2015 | 557 | 2015 |
Two families of chaperonin: physiology and mechanism AL Horwich, WA Fenton, E Chapman, GW Farr Annu. Rev. Cell Dev. Biol. 23 (1), 115-145, 2007 | 543 | 2007 |
Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility E Chapman, MD Best, SR Hanson, CH Wong Angewandte Chemie International Edition 43 (27), 3526-3548, 2004 | 386 | 2004 |
Modulating NRF2 in disease: timing is everything M Dodson, MR de la Vega, AB Cholanians, CJ Schmidlin, E Chapman, ... Annual review of pharmacology and toxicology 59 (1), 555-575, 2019 | 378 | 2019 |
Hrd1 suppresses Nrf2-mediated cellular protection during liver cirrhosis T Wu, F Zhao, B Gao, C Tan, N Yagishita, T Nakajima, PK Wong, ... Genes & development 28 (7), 708-722, 2014 | 335 | 2014 |
Oncogenic KRAS confers chemoresistance by upregulating NRF2 S Tao, S Wang, SJ Moghaddam, A Ooi, E Chapman, PK Wong, DD Zhang Cancer research 74 (24), 7430-7441, 2014 | 279 | 2014 |
Molecular mechanisms of Nrf2 regulation and how these influence chemical modulation for disease intervention B Harder, T Jiang, T Wu, S Tao, MR de la Vega, W Tian, E Chapman, ... Biochemical Society Transactions 43 (4), 680-686, 2015 | 179 | 2015 |
Global aggregation of newly translated proteins in an Escherichia coli strain deficient of the chaperonin GroEL E Chapman, GW Farr, R Usaite, K Furtak, WA Fenton, TK Chaudhuri, ... Proceedings of the National Academy of Sciences 103 (43), 15800-15805, 2006 | 154 | 2006 |
Non-enzymatic lysine lactoylation of glycolytic enzymes DO Gaffney, EQ Jennings, CC Anderson, JO Marentette, T Shi, ... Cell chemical biology 27 (2), 206-213. e6, 2020 | 149 | 2020 |
Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides MD Burkart, M Izumi, E Chapman, CH Lin, CH Wong The Journal of organic chemistry 65 (18), 5565-5574, 2000 | 136 | 2000 |
USP15 negatively regulates Nrf2 through deubiquitination of Keap1 NF Villeneuve, W Tian, T Wu, Z Sun, A Lau, E Chapman, D Fang, ... Molecular cell 51 (1), 68-79, 2013 | 117 | 2013 |
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8 A Anandhan, M Dodson, A Shakya, J Chen, P Liu, Y Wei, H Tan, Q Wang, ... Science advances 9 (5), eade9585, 2023 | 114 | 2023 |
The effects of NRF2 modulation on the initiation and progression of chemically and genetically induced lung cancer S Tao, M Rojo de la Vega, E Chapman, A Ooi, DD Zhang Molecular carcinogenesis 57 (2), 182-192, 2018 | 111 | 2018 |
Brusatol overcomes chemoresistance through inhibition of protein translation B Harder, W Tian, JJ La Clair, AC Tan, A Ooi, E Chapman, DD Zhang Molecular Carcinogenesis 56 (5), 1493-1500, 2017 | 106 | 2017 |
Inhibitors of the AAA+ chaperone p97 E Chapman, N Maksim, F De la Cruz, JJ La Clair Molecules 20 (2), 3027-3049, 2015 | 102 | 2015 |
Mutational analysis of backbone hydrogen bonds in staphylococcal nuclease E Chapman, JS Thorson, PG Schultz Journal of the American Chemical Society 119 (30), 7151-7152, 1997 | 100 | 1997 |
p97 negatively regulates NRF2 by extracting ubiquitylated NRF2 from the KEAP1-CUL3 E3 complex S Tao, P Liu, G Luo, M Rojo de la Vega, H Chen, T Wu, J Tillotson, ... Molecular and cellular biology 37 (8), e00660-16, 2017 | 94 | 2017 |
The complexities of p97 function in health and disease E Chapman, AN Fry, MJ Kang Molecular bioSystems 7 (3), 700-710, 2011 | 87 | 2011 |
The role of natural products in revealing NRF2 function DD Zhang, E Chapman Natural product reports 37 (6), 797-826, 2020 | 85 | 2020 |