| A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment A Rybak, H Fuchs, L Smirnova, C Brandt, EE Pohl, R Nitsch, FG Wulczyn Nature cell biology 10 (8), 987-993, 2008 | 998 | 2008 |
| Regulation of miRNA expression during neural cell specification L Smirnova, A Gräfe, A Seiler, S Schumacher, R Nitsch, FG Wulczyn European Journal of Neuroscience 21 (6), 1469-1477, 2005 | 881 | 2005 |
| The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2 A Rybak, H Fuchs, K Hadian, L Smirnova, EA Wulczyn, G Michel, R Nitsch, ... Nature cell biology 11 (12), 1411-1420, 2009 | 294 | 2009 |
| Metabolomics in toxicology and preclinical research T Ramirez, M Daneshian, H Kamp, FY Bois, MR Clench, M Coen, ... Altex 30 (2), 209, 2013 | 248 | 2013 |
| Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development U Marx, T Akabane, TB Andersson, E Baker, M Beilmann, S Beken, ... Altex 37 (3), 365, 2020 | 222 | 2020 |
| A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity D Pamies, P Barrera, K Block, G Makri, A Kumar, D Wiersma, L Smirnova, ... Altex 34 (3), 362, 2017 | 204 | 2017 |
| Food for Thought…: Developmental Neurotoxicity–Challenges in the 21st Century and In Vitro Opportunities L Smirnova, HT Hogberg, M Leist, T Hartung Altex 31 (2), 129, 2014 | 179 | 2014 |
| Integrated Testing Strategies (ITS) for safety assessment. C Rovida, N Alépée, AM Api, DA Basketter, F y Bois, F Caloni, E Corsini, ... ALTEX-Alternatives to Animal Experimentations 32 (1), 25-40, 2015 | 172 | 2015 |
| Good cell culture practice for stem cells and stem-cell-derived models D Pamies, A Bal-Price, A Simeonov, D Tagle, D Allen, D Gerhold, D Yin, ... | 162 | 2017 |
| Infectability of human BrainSphere neurons suggests neurotropism of SARS-CoV-2 CK Bullen, HT Hogberg, A Bahadirli-Talbott, WR Bishai, T Hartung, ... ALTEX-Alternatives to animal experimentation 37 (4), 665-671, 2020 | 159 | 2020 |
| Animal testing and its alternatives–The most important omics is economics L Meigs, L Smirnova, C Rovida, M Leist, T Hartung ALTEX-Alternatives to animal experimentation 35 (3), 275-305, 2018 | 157 | 2018 |
| In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities BZ Schmidt, M Lehmann, S Gutbier, E Nembo, S Noel, L Smirnova, ... Archives of toxicology 91, 1-33, 2017 | 141 | 2017 |
| Rotenone exerts developmental neurotoxicity in a human brain spheroid model D Pamies, K Block, P Lau, L Gribaldo, CA Pardo, P Barreras, L Smirnova, ... Toxicology and applied pharmacology 354, 101-114, 2018 | 127 | 2018 |
| A LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis L Smirnova, G Harris, J Delp, M Valadares, D Pamies, HT Hogberg, ... Archives of toxicology 90, 2725-2743, 2016 | 113 | 2016 |
| t4 workshop report: pathways of toxicity A Kleensang, A Maertens, M Rosenberg, S Fitzpatrick, J Lamb, ... Altex 31 (1), 53, 2014 | 109 | 2014 |
| Organoid intelligence (OI): the new frontier in biocomputing and intelligence-in-a-dish L Smirnova, BS Caffo, DH Gracias, Q Huang, IE Morales Pantoja, B Tang, ... Frontiers in Science 1, 1017235, 2023 | 85 | 2023 |
| Suitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery PEC Leite, MR Pereira, G Harris, D Pamies, LMG Dos Santos, ... Particle and fibre toxicology 16, 1-20, 2019 | 80 | 2019 |
| Toward a 3D model of human brain development for studying gene/environment interactions HT Hogberg, J Bressler, KM Christian, G Harris, G Makri, C O'Driscoll, ... Stem Cell Research & Therapy 4, 1-7, 2013 | 76 | 2013 |
| Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, PC Chandrasekera, ... Altex 37 (4), 579, 2020 | 75 | 2020 |
| Cellular resilience L Smirnova, G Harris, M Leist, T Hartung | 70 | 2015 |
