μ-Opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization J McPherson, G Rivero, M Baptist, J Llorente, S Al-Sabah, C Krasel, ... Molecular pharmacology 78 (4), 756-766, 2010 | 261 | 2010 |
A model for receptor–peptide binding at the glucagon‐like peptide‐1 (GLP‐1) receptor through the analysis of truncated ligands and receptors S Al‐Sabah, D Donnelly British journal of pharmacology 140 (2), 339-346, 2003 | 129 | 2003 |
Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin I AlKhairi, P Cherian, M Abu-Farha, AA Madhoun, R Nizam, M Melhem, ... Cells 8 (10), 1283, 2019 | 74 | 2019 |
Dual role of the β2-adrenergic receptor C terminus for the binding of β-arrestin and receptor internalization C Krasel, U Zabel, K Lorenz, S Reiner, S Al-Sabah, MJ Lohse Journal of Biological Chemistry 283 (46), 31840-31848, 2008 | 62 | 2008 |
The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists S Al-Sabah, D Donnelly FEBS letters 553 (3), 342-346, 2003 | 55 | 2003 |
Peptide binding at the GLP-1 receptor R Mann, N Nasr, D Hadden, J Sinfield, F Abidi, S Al-Sabah, ... Biochemical Society transactions 35 (4), 713-716, 2007 | 49 | 2007 |
The GIP receptor displays higher basal activity than the GLP-1 receptor but does not recruit GRK2 or arrestin3 effectively S Al-Sabah, M Al-Fulaij, G Shaaban, HA Ahmed, RJ Mann, D Donnelly, ... PloS one 9 (9), e106890, 2014 | 48 | 2014 |
Dual single-scission event analysis of constitutive transferrin receptor (TfR) endocytosis and ligand-triggered β2-adrenergic receptor (β2AR) or Mu-opioid receptor (MOR … M Lampe, F Pierre, S Al-Sabah, C Krasel, CJ Merrifield Molecular biology of the cell 25 (19), 3070-3080, 2014 | 36 | 2014 |
Engineered hyperphosphorylation of the β2-adrenoceptor prolongs arrestin-3 binding and induces arrestin internalization D Zindel, AJ Butcher, S Al-Sabah, P Lanzerstorfer, J Weghuber, AB Tobin, ... Molecular pharmacology 87 (2), 349-362, 2015 | 30 | 2015 |
FRET-based detection of M1 muscarinic acetylcholine receptor activation by orthosteric and allosteric agonists D Markovic, J Holdich, S Al-Sabah, R Mistry, C Krasel, MP Mahaut-Smith, ... PloS one 7 (1), 2012 | 29 | 2012 |
Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket RJ Mann, S Al-Sabah, RL De Maturana, JK Sinfield, D Donnelly Peptides 31 (12), 2289-2293, 2010 | 27 | 2010 |
Molecular Pharmacology of the Incretin Receptors S Al-Sabah Medical Principles and Practice 25 (Suppl. 1), 15-21, 2016 | 26 | 2016 |
A Dual GLP-1/GIP Receptor Agonist Does Not Antagonize Glucagon at Its Receptor but May Act as a Biased Agonist at the GLP-1 Receptor N Al-Zamel, S Al-Sabah, Y Luqmani, L Adi, S Chacko, TD Schneider, ... International Journal of Molecular Sciences 20 (14), 3532, 2019 | 21 | 2019 |
Selectivity of peptide ligands for the human incretin receptors expressed in HEK-293 cells S Al-Sabah, M Al-Fulaij, HA Ahmed European journal of pharmacology 741, 311-315, 2014 | 20 | 2014 |
The primary ligand-binding interaction at the GLP-1 receptor is via the putative helix of the peptide agonists S Al-Sabah, D Donnelly Protein and peptide letters 11 (1), 9-14, 2004 | 18 | 2004 |
Effect of Sleeve gastrectomy on The Expression of Meteorin-Like (METRNL) and Irisin (FNDC5) in Muscle and Brown Adipose Tissue and its Impact on Uncoupling Proteins (UCPs) in … MH Jamal, M Abu-Farha, G Al-Khaledi, S Al-Sabah, H Ali, P Cherian, ... Surgery for Obesity and Related Diseases, 2020 | 15 | 2020 |
Investigating Factors Involved in Post Laparoscopic Sleeve Gastrectomy (LSG) Neuropathy A Alsabah, S Al Sabah, S Al-Sabah, A Al-Serri, E Al Haddad, WM Renno Obesity surgery 27 (5), 1271-1276, 2017 | 15 | 2017 |
Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor G Shaaban, M Oriowo, S Al-Sabah Molecules 22 (1), 22, 2017 | 13 | 2017 |
Incretin Response to a Standard Test Meal in a Rat Model of Sleeve Gastrectomy with Diet-Induced Obesity S Al-Sabah, F Alasfar, G Al-Khaledi, R Dinesh, M Al-Saleh, H Abul Obesity surgery 24 (1), 95-101, 2014 | 13 | 2014 |
Association Between Factors Involved in Bone Remodeling (Osteoactivin and OPG) With Plasma Levels of Irisin and Meteorin-Like Protein in People With T2D and Obesity P Cherian, I Al-Khairi, M Jamal, S Al-Sabah, H Ali, C Dsouza, E Alshawaf, ... Frontiers in Endocrinology 12, 2021 | 12 | 2021 |