The RNA silencing endonuclease Argonaute 2 mediates specific antiviral immunity in Drosophila melanogaster RP Van Rij, MC Saleh, B Berry, C Foo, A Houk, C Antoniewski, R Andino Genes & development 20 (21), 2985-2995, 2006 | 669 | 2006 |
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing MC Saleh, RP van Rij, A Hekele, A Gillis, E Foley, PH O'Farrell, R Andino Nature cell biology 8 (8), 793-802, 2006 | 617 | 2006 |
Antiviral immunity in Drosophila requires systemic RNA interference spread MC Saleh, M Tassetto, RP Van Rij, B Goic, V Gausson, B Berry, ... Nature 458 (7236), 346-350, 2009 | 340 | 2009 |
Immuno-activation with anti-CD3 and recombinant human IL-2 in HIV-1-infected patients on potent antiretroviral therapy JM Prins, S Jurriaans, RME van Praag, H Blaak, R van Rij, ... Aids 13 (17), 2405-2410, 1999 | 310 | 1999 |
MDA5 Detects the double-stranded RNA replicative form in picornavirus-infected cells Q Feng, SV Hato, MA Langereis, J Zoll, R Virgen-Slane, A Peisley, S Hur, ... Cell reports 2, 1187-1196, 2012 | 277 | 2012 |
The long and short of antiviral defense: small RNA-based immunity in insects AW Bronkhorst, RP van Rij Current opinion in virology 7, 19-28, 2014 | 256 | 2014 |
Arbovirus-derived piRNAs exhibit a ping-pong signature in mosquito cells N Vodovar, AW Bronkhorst, KWR van Cleef, P Miesen, H Blanc, ... PloS one 7 (1), e30861, 2012 | 243 | 2012 |
Distinct sets of PIWI proteins produce arbovirus and transposon-derived piRNAs in Aedes aegypti mosquito cells P Miesen, E Girardi, RP van Rij Nucleic acids research 43 (13), 6545-6556, 2015 | 197 | 2015 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell Stem Cell 29 (2), 217-231. e8, 2022 | 181 | 2022 |
Beyond RNAi: Antiviral defense strategies in< i> Drosophila</i> and Mosquito SH Merkling, RP van Rij Journal of Insect Physiology 59, 159-170, 2012 | 174 | 2012 |
The role of a stromal cell-derived factor-1 chemokine gene variant in the clinical course of HIV-1 infection RP van Rij, S Broersen, J Goudsmit, RA Coutinho, H Schuitemaker Aids 12 (9), F85-F90, 1998 | 164 | 1998 |
PIWIs go viral: arbovirus-derived piRNAs in vector mosquitoes P Miesen, J Joosten, RP van Rij PLoS pathogens 12 (12), e1006017, 2016 | 161 | 2016 |
The DNA virus Invertebrate iridescent virus 6 is a target of the Drosophila RNAi machinery AW Bronkhorst, KWR van Cleef, N Vodovar, İA İnce, H Blanc, JM Vlak, ... Proceedings of the National Academy of Sciences 109 (51), E3604-E3613, 2012 | 160 | 2012 |
Comparative genomics shows that viral integrations are abundant and express piRNAs in the arboviral vectors Aedes aegypti and Aedes albopictus U Palatini, P Miesen, R Carballar-Lejarazu, L Ometto, E Rizzo, Z Tu, ... BMC genomics 18, 1-15, 2017 | 153 | 2017 |
Differential coreceptor expression allows for independent evolution of non–syncytium-inducing and syncytium-inducing HIV-1 RP van Rij, H Blaak, JA Visser, M Brouwer, R Rientsma, S Broersen, ... The journal of clinical investigation 106 (8), 1039-1052, 2000 | 148 | 2000 |
Noncoding subgenomic flavivirus RNA is processed by the mosquito RNA interference machinery and determines West Nile virus transmission by Culex pipiens mosquitoes GP Göertz, JJ Fros, P Miesen, CBF Vogels, ML Van Der Bent, ... Journal of virology 90 (22), 10145-10159, 2016 | 135 | 2016 |
Comparative Usutu and West Nile virus transmission potential by local Culex pipiens mosquitoes in north-western Europe JJ Fros, P Miesen, CB Vogels, P Gaibani, V Sambri, BE Martina, ... One Health 1, 31-36, 2015 | 133 | 2015 |
Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAs P Miesen, A Ivens, AH Buck, RP van Rij PLoS neglected tropical diseases 10 (2), e0004452, 2016 | 130 | 2016 |
Adaptation to promiscuous usage of chemokine receptors is not a prerequisite for human immunodeficiency virus type 1 disease progression AM de Roda Husman, RP van Rij, H Blaak, S Broersen, H Schuitemaker The Journal of infectious diseases 180 (4), 1106-1115, 1999 | 130 | 1999 |
Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens V Doublet, Y Poeschl, A Gogol-Döring, C Alaux, D Annoscia, C Aurori, ... BMC genomics 18, 1-17, 2017 | 129 | 2017 |