Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. BA Masters, EJ Kelly, CJ Quaife, RL Brinster, RD Palmiter Proceedings of the National Academy of Sciences 91 (2), 584-588, 1994 | 758 | 1994 |
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epithelia CJ Quaife, SD Findley, JC Erickson, GJ Froelick, EJ Kelly, BP Zambrowicz, ... Biochemistry 33 (23), 7250-7259, 1994 | 737 | 1994 |
Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles BA Masters, CJ Quaife, JC Erickson, EJ Kelly, GJ Froelick, ... Journal of Neuroscience 14 (10), 5844-5857, 1994 | 436 | 1994 |
Metallothionein I and II protect against zinc deficiency and zinc toxicity in mice EJ Kelly, CJ Quaife, GJ Froelick, RD Palmiter The Journal of nutrition 126 (7), 1782-1790, 1996 | 325 | 1996 |
Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice MF Hebert, X Ma, SB Naraharisetti, KM Krudys, JG Umans, GDV Hankins, ... Clinical Pharmacology & Therapeutics 85 (6), 607-614, 2009 | 260 | 2009 |
Functional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation AS Payne, EJ Kelly, JD Gitlin Proceedings of the National Academy of Sciences 95 (18), 10854-10859, 1998 | 258 | 1998 |
Functional coupling of human microphysiology systems: intestine, liver, kidney proximal tubule, blood-brain barrier and skeletal muscle L Vernetti, A Gough, N Baetz, S Blutt, JR Broughman, JA Brown, ... Scientific reports 7 (1), 42296, 2017 | 251 | 2017 |
Development of a microphysiological model of human kidney proximal tubule function EJ Weber, A Chapron, BD Chapron, JL Voellinger, KA Lidberg, CK Yeung, ... Kidney international 90 (3), 627-637, 2016 | 243 | 2016 |
Pharmacokinetics of metformin during pregnancy S Eyal, TR Easterling, D Carr, JG Umans, M Miodovnik, GDV Hankins, ... Drug Metabolism and Disposition 38 (5), 833-840, 2010 | 241 | 2010 |
A murine model of Menkes disease reveals a physiological function of metallothionein EJ Kelly, RD Palmiter Nature genetics 13 (2), 219-222, 1996 | 168 | 1996 |
A pair of adjacent glucocorticoid response elements regulate expression of two mouse metallothionein genes EJ Kelly, EP Sandgren, RL Brinster, RD Palmiter Proceedings of the National Academy of Sciences 94 (19), 10045-10050, 1997 | 153 | 1997 |
Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity SY Chang, EJ Weber, VS Sidorenko, A Chapron, CK Yeung, C Gao, ... JCI insight 2 (22), 2017 | 148 | 2017 |
Abundance of drug transporters in the human kidney cortex as quantified by quantitative targeted proteomics B Prasad, K Johnson, S Billington, C Lee, GW Chung, CDA Brown, ... Drug Metabolism and Disposition 44 (12), 1920-1924, 2016 | 143 | 2016 |
A quantitative approach to screen for nephrotoxic compounds in vitro M Adler, S Ramm, M Hafner, JL Muhlich, EM Gottwald, E Weber, A Jaklic, ... Journal of the American Society of Nephrology 27 (4), 1015-1028, 2016 | 129 | 2016 |
Role of CYP1A2 in the Hepatotoxicity of Acetaminophen: Investigations UsingCyp1a2Null Mice RP Tonge, EJ Kelly, SA Bruschi, T Kalhorn, DL Eaton, DW Nebert, ... Toxicology and applied pharmacology 153 (1), 102-108, 1998 | 122 | 1998 |
Expression and characterization of CYP4V2 as a fatty acid ω-hydroxylase M Nakano, EJ Kelly, AE Rettie Drug metabolism and disposition 37 (11), 2119-2122, 2009 | 119 | 2009 |
Transporter expression in liver tissue from subjects with alcoholic or hepatitis C cirrhosis quantified by targeted quantitative proteomics L Wang, C Collins, EJ Kelly, X Chu, AS Ray, L Salphati, G Xiao, C Lee, ... Drug Metabolism and Disposition 44 (11), 1752-1758, 2016 | 115 | 2016 |
CYP4V2 in Bietti's crystalline dystrophy: ocular localization, metabolism of ω-3-polyunsaturated fatty acids, and functional deficit of the p. H331P variant M Nakano, EJ Kelly, C Wiek, H Hanenberg, AE Rettie Molecular pharmacology 82 (4), 679-686, 2012 | 101 | 2012 |
Identification of the C5a des Arg cochemotaxin. Homology with vitamin D-binding protein (group-specific component globulin). HD Perez, E Kelly, D Chenoweth, F Elfman The Journal of clinical investigation 82 (1), 360-363, 1988 | 94 | 1988 |
Defective polymorphonuclear leukocyte formyl peptide receptor (s) in juvenile periodontitis. HD Perez, E Kelly, F Elfman, G Armitage, J Winkler The Journal of clinical investigation 87 (3), 971-976, 1991 | 90 | 1991 |