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Derek T O'Hagan
Derek T O'Hagan
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Emerging concepts in the science of vaccine adjuvants
B Pulendran, P S. Arunachalam, DT O’Hagan
Nature Reviews Drug Discovery 20 (6), 454-475, 2021
8752021
Nonviral delivery of self-amplifying RNA vaccines
AJ Geall, A Verma, GR Otten, CA Shaw, A Hekele, K Banerjee, Y Cu, ...
Proceedings of the National Academy of Sciences 109 (36), 14604-14609, 2012
7262012
Advances in vaccine adjuvants
M Singh, D O'Hagan
Nature biotechnology 17 (11), 1075-1081, 1999
7061999
Uptake of particulate vaccine adjuvants by dendritic cells activates the NALP3 inflammasome
FA Sharp, D Ruane, B Claass, E Creagh, J Harris, P Malyala, M Singh, ...
Proceedings of the National Academy of Sciences 106 (3), 870-875, 2009
6632009
Cationic microparticles: a potent delivery system for DNA vaccines
M Singh, M Briones, G Ott, D O'Hagan
Proceedings of the National Academy of Sciences 97 (2), 811-816, 2000
6272000
Molecular and cellular signatures of human vaccine adjuvants
F Mosca, E Tritto, A Muzzi, E Monaci, F Bagnoli, C Iavarone, D O'Hagan, ...
Proceedings of the National Academy of Sciences 105 (30), 10501-10506, 2008
6082008
Recent advances in the discovery and delivery of vaccine adjuvants
DT O'Hagan, NM Valiante
Nature Reviews Drug Discovery 2 (9), 727-735, 2003
5892003
The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells
A Seubert, E Monaci, M Pizza, DT O’Hagan, A Wack
The journal of Immunology 180 (8), 5402-5412, 2008
5402008
The mechanism of action of MF59–an innately attractive adjuvant formulation
DT O’hagan, GS Ott, E De Gregorio, A Seubert
Vaccine 30 (29), 4341-4348, 2012
5062012
Vaccine adjuvants alum and MF59 induce rapid recruitment of neutrophils and monocytes that participate in antigen transport to draining lymph nodes
S Calabro, M Tortoli, BC Baudner, A Pacitto, M Cortese, DT O’Hagan, ...
Vaccine 29 (9), 1812-1823, 2011
4962011
Recent developments in adjuvants for vaccines against infectious diseases
DT O'Hagan, ML MacKichan, M Singh
Biomolecular engineering 18 (3), 69-85, 2001
4702001
The preparation and characterization of poly (lactide-co-glycolide) microparticles. II. The entrapment of a model protein using a (water-in-oil)-in-water emulsion solvent …
H Jeffery, SS Davis, DT O'Hagan
Pharmaceutical research 10, 362-368, 1993
4391993
The history of MF59® adjuvant: a phoenix that arose from the ashes
DT O’Hagan, GS Ott, GV Nest, R Rappuoli, GD Giudice
Expert review of vaccines 12 (1), 13-30, 2013
3832013
Biodegradable microparticles as controlled release antigen delivery systems.
DT O'hagan, D Rahman, JP McGee, H Jeffery, MC Davies, P Williams, ...
Immunology 73 (2), 239, 1991
3781991
Recent advances in vaccine adjuvants
M Singh, DT O'Hagan
Pharmaceutical research 19, 715-728, 2002
3502002
A cationic nanoemulsion for the delivery of next-generation RNA vaccines
LA Brito, M Chan, CA Shaw, A Hekele, T Carsillo, M Schaefer, J Archer, ...
Molecular Therapy 22 (12), 2118-2129, 2014
3452014
The path to a successful vaccine adjuvant–‘the long and winding road’
DT O’Hagan, E De Gregorio
Drug discovery today 14 (11-12), 541-551, 2009
3412009
Optimizing the utilization of aluminum adjuvants in vaccines: you might just get what you want
H HogenEsch, DT O’Hagan, CB Fox
npj Vaccines 3 (1), 51, 2018
3372018
Nanoparticles and microparticles as vaccine-delivery systems
M Singh, A Chakrapani, D O’Hagan
Expert review of vaccines 6 (5), 797-808, 2007
3312007
MF59 is a safe and potent vaccine adjuvant that enhances protection against influenza virus infection
DT O’Hagan
Expert review of vaccines 6 (5), 699-710, 2007
3272007
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