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Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase AK Madiraju, DM Erion, Y Rahimi, XM Zhang, DT Braddock, RA Albright, ... Nature 510 (7506), 542-546, 2014 | 1356 | 2014 |
Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch P Cohen, JD Levy, Y Zhang, A Frontini, DP Kolodin, KJ Svensson, JC Lo, ... Cell 156 (1), 304-316, 2014 | 921 | 2014 |
Hepatic acetyl CoA links adipose tissue inflammation to hepatic insulin resistance and type 2 diabetes RJ Perry, JPG Camporez, R Kursawe, PM Titchenell, D Zhang, CJ Perry, ... Cell 160 (4), 745-758, 2015 | 715 | 2015 |
UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis K Ikeda, Q Kang, T Yoneshiro, JP Camporez, H Maki, M Homma, ... Nature medicine 23 (12), 1454-1465, 2017 | 516 | 2017 |
The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis JE Dominy, Y Lee, MP Jedrychowski, H Chim, MJ Jurczak, JP Camporez, ... Molecular cell 48 (6), 900-913, 2012 | 311 | 2012 |
An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ AS Banks, FE McAllister, JPG Camporez, PJH Zushin, MJ Jurczak, ... Nature 517 (7534), 391-395, 2015 | 307 | 2015 |
Regulation of adipose tissue inflammation by interleukin 6 MS Han, A White, RJ Perry, JP Camporez, J Hidalgo, GI Shulman, ... Proceedings of the National Academy of Sciences 117 (6), 2751-2760, 2020 | 278 | 2020 |
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo AK Madiraju, Y Qiu, RJ Perry, Y Rahimi, XM Zhang, D Zhang, ... Nature medicine 24 (9), 1384-1394, 2018 | 260 | 2018 |
Cyclin D1–Cdk4 controls glucose metabolism independently of cell cycle progression Y Lee, JE Dominy, YJ Choi, M Jurczak, N Tolliday, JP Camporez, H Chim, ... Nature 510 (7506), 547-551, 2014 | 249 | 2014 |
Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice JPG Camporez, FR Jornayvaz, MC Petersen, D Pesta, BA Guigni, J Serr, ... Endocrinology 154 (9), 3099-3109, 2013 | 242 | 2013 |
Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids DF Vatner, SK Majumdar, N Kumashiro, MC Petersen, Y Rahimi, AK Gattu, ... Proceedings of the national academy of sciences 112 (4), 1143-1148, 2015 | 240 | 2015 |
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis RJ Perry, XM Zhang, D Zhang, N Kumashiro, JPG Camporez, GW Cline, ... Nature medicine 20 (7), 759-763, 2014 | 210 | 2014 |
Cellular mechanism by which estradiol protects female ovariectomized mice from high-fat diet-induced hepatic and muscle insulin resistance JPG Camporez, FR Jornayvaz, HY Lee, S Kanda, BA Guigni, M Kahn, ... Endocrinology 154 (3), 1021-1028, 2013 | 208 | 2013 |
Lacteal junction zippering protects against diet-induced obesity F Zhang, G Zarkada, J Han, J Li, A Dubrac, R Ola, G Genet, K Boyé, ... Science 361 (6402), 599-603, 2018 | 191 | 2018 |
Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice JPG Camporez, MC Petersen, A Abudukadier, GV Moreira, MJ Jurczak, ... Proceedings of the National Academy of Sciences 113 (8), 2212-2217, 2016 | 184 | 2016 |
Selective chemical inhibition of PGC-1α gluconeogenic activity ameliorates type 2 diabetes K Sharabi, H Lin, CDJ Tavares, JE Dominy, JP Camporez, RJ Perry, ... Cell 169 (1), 148-160. e15, 2017 | 180 | 2017 |
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance JL Cantley, T Yoshimura, JPG Camporez, D Zhang, FR Jornayvaz, ... Proceedings of the National Academy of Sciences 110 (5), 1869-1874, 2013 | 176 | 2013 |
Absence of carbohydrate response element binding protein in adipocytes causes systemic insulin resistance and impairs glucose transport A Vijayakumar, P Aryal, J Wen, I Syed, RP Vazirani, PM Moraes-Vieira, ... Cell reports 21 (4), 1021-1035, 2017 | 137 | 2017 |
Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans N Gómez-Banoy, JS Guseh, GE Li, A Rubio-Navarro, T Chen, BA Poirier, ... Nature medicine 25 (11), 1739-1747, 2019 | 133 | 2019 |