MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy M Owyong, J Chou, RJE van den Bijgaart, N Kong, G Efe, C Maynard, ... Life science alliance 2 (6), 2019 | 99 | 2019 |
Key genetic determinants driving esophageal squamous cell carcinoma initiation and immune evasion KP Ko, Y Huang, S Zhang, G Zou, B Kim, J Zhang, S Jun, C Martin, ... Gastroenterology 165 (3), 613-628. e20, 2023 | 28 | 2023 |
Overcoming barriers of age to enhance efficacy of cancer immunotherapy: the clout of the extracellular matrix M Owyong, G Efe, M Owyong, AJ Abbasi, V Sitarama, V Plaks Frontiers in Cell and Developmental Biology 6, 19, 2018 | 25 | 2018 |
Mutant p53 regulates Survivin to foster lung metastasis Q Tang, G Efe, AM Chiarella, J Leung, M Chen, T Yamazoe, Z Su, ... Genes & Development 35 (7-8), 528-541, 2021 | 23 | 2021 |
Cancer immunotherapy getting brainy: visualizing the distinctive CNS metastatic niche to illuminate therapeutic resistance M Owyong, N Hosseini-Nassab, G Efe, A Honkala, RJE van den Bijgaart, ... Drug Resistance Updates 33, 23-35, 2017 | 20 | 2017 |
Rab11‐FIP1 mediates epithelial‐mesenchymal transition and invasion in esophageal cancer Q Tang, A Lento, K Suzuki, G Efe, T Karakasheva, A Long, V Giroux, ... EMBO reports 22 (2), e48351, 2021 | 18 | 2021 |
p53 gain-of-function mutation induces metastasis via Brd4-dependent Csf-1 expression G Efe, KJ Dunbar, K Sugiura, K Cunningham, S Carcamo, S Karaiskos, ... Cancer Discovery 13 (12), 2632-2651, 2023 | 16 | 2023 |
Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells A Garcia-Diaz, G Efe, K Kabra, A Patel, ER Lowry, NA Shneider, B Corneo, ... Neuroscience 450, 48-56, 2020 | 12 | 2020 |
Roles of estrogen receptor-alpha in mediating life span: the hypothalamic deregulation hypothesis AM Gouw, G Efe, R Barakat, A Preecha, M Mehdizadeh, SA Garan, ... Physiological genomics 49 (2), 88-95, 2017 | 12 | 2017 |
Tumor-derived CCL5 recruits cancer-associated fibroblasts and promotes tumor cell proliferation in esophageal squamous cell carcinoma KJ Dunbar, TA Karakasheva, Q Tang, G Efe, EW Lin, M Harris, V Sahu, ... Molecular Cancer Research 21 (7), 741-752, 2023 | 9 | 2023 |
Engineered hydrogel reveals contribution of matrix mechanics to esophageal adenocarcinoma and identifies matrix-activated therapeutic targets R Cruz-Acuña, SW Kariuki, K Sugiura, S Karaiskos, EM Plaster, C Loebel, ... The Journal of Clinical Investigation 133 (23), 2023 | 7 | 2023 |
p53 at the crossroads of tumor immunity G Efe, AK Rustgi, C Prives Nature Cancer 5 (7), 983-995, 2024 | 5 | 2024 |
Abstract PO-106: The extrinsic and modulatory effects of CSF-1/CSF-1R signaling in generating an immunosuppressive pancreatic cancer tumor microenvironment and promoting metastasis G Efe, K Suzuki, JR Pitarresi, AM Chiarella, AL Li, AK Rustgi Cancer Research 81 (22_Supplement), PO-106-PO-106, 2021 | 1 | 2021 |
Abstract A030: Polycomb repressive complex 2 (PRC2) mediates the epigenetic regulation of cancer-associated fibroblasts in esophageal cancer KJ Dunbar, RN Fernandez de Bobadil, KM Cunningham, E Esquea, G Efe, ... Cancer Research 84 (22_Supplement), A030-A030, 2024 | | 2024 |
Mdm2 requires Sprouty4 to regulate focal adhesion formation and metastasis independent of p53 RM de Queiroz, G Efe, A Guzman, N Hashimoto, Y Kawashima, T Tanaka, ... Nature Communications 15 (1), 7132, 2024 | | 2024 |
Tumor niche network-defined subtypes predict immunotherapy response of esophageal squamous cell cancer KP Ko, S Zhang, Y Huang, B Kim, G Zou, S Jun, J Zhang, Y Zhao, ... Iscience 27 (5), 2024 | | 2024 |
Engineered hydrogel elucidates contributions of matrix mechanics to pathobiology of adenocarcinoma and identify matrix-activated therapeutic targets R Cruz-Acuna, SW Kariuki, K Sugiura, S Karaiskos, EM Plaster, C Loebel, ... Cancer Research 84 (6_Supplement), 4268-4268, 2024 | | 2024 |
p53-R172H mutation confers gain-of-function properties and promotes metastasis in squamous cell carcinoma G Efe, K Cunningham, RNF de Bobadilla, KJ Dunbar, K Sugiura, ... Cancer Research 84 (6_Supplement), 1270-1270, 2024 | | 2024 |
Mutant p53 regulates cancer cell invasion in complex three-dimensional environments through mevalonate pathway-dependent Rho/ROCK signaling. A Guzman, T Kawase, AJ Devanny, G Efe, R Navaridas, K Yu, ... bioRxiv, 2024.10. 13.618100, 2024 | | 2024 |
Sprouty4 is required for Mdm2 regulation of invasion, focal adhesion formation and metastasis in cells lacking p53 RM Queiroz, G Efe, A Guzman, N Hashimoto, Y Kawashima, T Tanaka, ... bioRxiv, 2023.05. 08.539890, 2023 | | 2023 |