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Jinfan Wang
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Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation
CP Lapointe, R Grosely, AG Johnson, J Wang, IS Fernández, JD Puglisi
Proceedings of the National Academy of Sciences 118 (6), e2017715118, 2021
1612021
How 2'-O-Methylation in mRNA Disrupts tRNA Decoding during Translation Elongation
J Choi, G Indrisiunaite, H DeMirci, KW Ieong, J Wang, A Petrov, ...
Biophysical Journal 114 (3), 592a, 2018
1202018
How messenger RNA and nascent chain sequences regulate translation elongation
J Choi, R Grosely, A Prabhakar, CP Lapointe, J Wang, JD Puglisi
Annual review of biochemistry 87 (1), 421-449, 2018
792018
eIF5B gates the transition from translation initiation to elongation
J Wang, AG Johnson, CP Lapointe, J Choi, A Prabhakar, DH Chen, ...
Nature 573, 605–608, 2019
672019
Dynamics of the context-specific translation arrest by chloramphenicol and linezolid
J Choi, J Marks, J Zhang, DH Chen, J Wang, N Vázquez-Laslop, ...
Nature chemical biology 16 (3), 310-317, 2020
592020
Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation
J Wang, BS Shin, C Alvarado, JR Kim, J Bohlen, TE Dever, JD Puglisi
Cell 185 (24), 4474-4487. e17, 2022
532022
Mechanisms that ensure speed and fidelity in eukaryotic translation termination
MR Lawson, LN Lessen, J Wang, A Prabhakar, NC Corsepius, R Green, ...
Science 373 (6557), 876-882, 2021
482021
RACK1 on and off the ribosome
AG Johnson, CP Lapointe, J Wang, NC Corsepius, J Choi, G Fuchs, ...
Rna 25 (7), 881-895, 2019
442019
Dynamic basis of fidelity and speed in translation: Coordinated multistep mechanisms of elongation and termination
A Prabhakar, J Choi, J Wang, A Petrov, JD Puglisi
Protein Science 26 (7), 1352-1362, 2017
432017
eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining
CP Lapointe, R Grosely, M Sokabe, C Alvarado, J Wang, E Montabana, ...
Nature 607 (7917), 185-190, 2022
382022
De novo design and synthesis of a 30-cistron translation-factor module
TR Shepherd, L Du, J Liljeruhm, fnm Samudyata, J Wang, MOD Sjödin, ...
Nucleic acids research 45 (18), 10895-10905, 2017
362017
Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex
J Wang, J Wang, BS Shin, JR Kim, TE Dever, JD Puglisi, IS Fernández
Nature Communications 11 (1), 5003, 2020
322020
Kinetics of tRNAPyl‐mediated amber suppression in Escherichia coli translation reveals unexpected limiting steps and competing reactions
J Wang, M Kwiatkowski, AC Forster
Biotechnology and Bioengineering 113 (7), 1552-1559, 2016
242016
Kinetics of ribosome-catalyzed polymerization using artificial aminoacyl-tRNA substrates clarifies inefficiencies and improvements
J Wang, M Kwiatkowski, AC Forster
ACS chemical biology 10 (10), 2187-2192, 2015
242015
Peptide Formation by N-Methyl Amino Acids in Translation Is Hastened by Higher pH and tRNAPro
J Wang, M Kwiatkowski, MY Pavlov, M Ehrenberg, AC Forster
ACS chemical biology 9 (6), 1303-1311, 2014
232014
Facile Synthesis of N-Acyl-aminoacyl-pCpA for Preparation of Mischarged Fully Ribo tRNA
M Kwiatkowski, J Wang, AC Forster
Bioconjugate chemistry 25 (11), 2086-2091, 2014
192014
Ribosomal peptide syntheses from activated substrates reveal rate limitation by an unexpected step at the peptidyl site
J Wang, M Kwiatkowski, AC Forster
Journal of the American Chemical Society 138 (48), 15587-15595, 2016
132016
Kinetics of d-Amino Acid Incorporation in Translation
J Liljeruhm, J Wang, M Kwiatkowski, S Sabari, AC Forster
ACS chemical biology 14 (2), 204-213, 2019
122019
Ribosomal incorporation of unnatural amino acids: lessons and improvements from fast kinetics studies
J Wang, AC Forster
Current opinion in chemical biology 46, 180-187, 2018
92018
Plasticity and conditional essentiality of modification enzymes for domain V of Escherichia coli 23S ribosomal RNA
J Liljeruhm, M Leppik, L Bao, T Truu, M Calvo-Noriega, NS Freyer, A Liiv, ...
RNA 28 (6), 796-807, 2022
42022
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