Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation CP Lapointe, R Grosely, AG Johnson, J Wang, IS Fernández, JD Puglisi Proceedings of the National Academy of Sciences 118 (6), e2017715118, 2021 | 161 | 2021 |
How 2'-O-Methylation in mRNA Disrupts tRNA Decoding during Translation Elongation J Choi, G Indrisiunaite, H DeMirci, KW Ieong, J Wang, A Petrov, ... Biophysical Journal 114 (3), 592a, 2018 | 120 | 2018 |
How messenger RNA and nascent chain sequences regulate translation elongation J Choi, R Grosely, A Prabhakar, CP Lapointe, J Wang, JD Puglisi Annual review of biochemistry 87 (1), 421-449, 2018 | 79 | 2018 |
eIF5B gates the transition from translation initiation to elongation J Wang, AG Johnson, CP Lapointe, J Choi, A Prabhakar, DH Chen, ... Nature 573, 605–608, 2019 | 67 | 2019 |
Dynamics of the context-specific translation arrest by chloramphenicol and linezolid J Choi, J Marks, J Zhang, DH Chen, J Wang, N Vázquez-Laslop, ... Nature chemical biology 16 (3), 310-317, 2020 | 59 | 2020 |
Rapid 40S scanning and its regulation by mRNA structure during eukaryotic translation initiation J Wang, BS Shin, C Alvarado, JR Kim, J Bohlen, TE Dever, JD Puglisi Cell 185 (24), 4474-4487. e17, 2022 | 53 | 2022 |
Mechanisms that ensure speed and fidelity in eukaryotic translation termination MR Lawson, LN Lessen, J Wang, A Prabhakar, NC Corsepius, R Green, ... Science 373 (6557), 876-882, 2021 | 48 | 2021 |
RACK1 on and off the ribosome AG Johnson, CP Lapointe, J Wang, NC Corsepius, J Choi, G Fuchs, ... Rna 25 (7), 881-895, 2019 | 44 | 2019 |
Dynamic basis of fidelity and speed in translation: Coordinated multistep mechanisms of elongation and termination A Prabhakar, J Choi, J Wang, A Petrov, JD Puglisi Protein Science 26 (7), 1352-1362, 2017 | 43 | 2017 |
eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining CP Lapointe, R Grosely, M Sokabe, C Alvarado, J Wang, E Montabana, ... Nature 607 (7917), 185-190, 2022 | 38 | 2022 |
De novo design and synthesis of a 30-cistron translation-factor module TR Shepherd, L Du, J Liljeruhm, fnm Samudyata, J Wang, MOD Sjödin, ... Nucleic acids research 45 (18), 10895-10905, 2017 | 36 | 2017 |
Structural basis for the transition from translation initiation to elongation by an 80S-eIF5B complex J Wang, J Wang, BS Shin, JR Kim, TE Dever, JD Puglisi, IS Fernández Nature Communications 11 (1), 5003, 2020 | 32 | 2020 |
Kinetics of tRNAPyl‐mediated amber suppression in Escherichia coli translation reveals unexpected limiting steps and competing reactions J Wang, M Kwiatkowski, AC Forster Biotechnology and Bioengineering 113 (7), 1552-1559, 2016 | 24 | 2016 |
Kinetics of ribosome-catalyzed polymerization using artificial aminoacyl-tRNA substrates clarifies inefficiencies and improvements J Wang, M Kwiatkowski, AC Forster ACS chemical biology 10 (10), 2187-2192, 2015 | 24 | 2015 |
Peptide Formation by N-Methyl Amino Acids in Translation Is Hastened by Higher pH and tRNAPro J Wang, M Kwiatkowski, MY Pavlov, M Ehrenberg, AC Forster ACS chemical biology 9 (6), 1303-1311, 2014 | 23 | 2014 |
Facile Synthesis of N-Acyl-aminoacyl-pCpA for Preparation of Mischarged Fully Ribo tRNA M Kwiatkowski, J Wang, AC Forster Bioconjugate chemistry 25 (11), 2086-2091, 2014 | 19 | 2014 |
Ribosomal peptide syntheses from activated substrates reveal rate limitation by an unexpected step at the peptidyl site J Wang, M Kwiatkowski, AC Forster Journal of the American Chemical Society 138 (48), 15587-15595, 2016 | 13 | 2016 |
Kinetics of d-Amino Acid Incorporation in Translation J Liljeruhm, J Wang, M Kwiatkowski, S Sabari, AC Forster ACS chemical biology 14 (2), 204-213, 2019 | 12 | 2019 |
Ribosomal incorporation of unnatural amino acids: lessons and improvements from fast kinetics studies J Wang, AC Forster Current opinion in chemical biology 46, 180-187, 2018 | 9 | 2018 |
Plasticity and conditional essentiality of modification enzymes for domain V of Escherichia coli 23S ribosomal RNA J Liljeruhm, M Leppik, L Bao, T Truu, M Calvo-Noriega, NS Freyer, A Liiv, ... RNA 28 (6), 796-807, 2022 | 4 | 2022 |