The biology of VEGF and its receptors N Ferrara, HP Gerber, J LeCouter Nature medicine 9 (6), 669-676, 2003 | 12453 | 2003 |
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer N Ferrara, KJ Hillan, HP Gerber, W Novotny Nature reviews Drug discovery 3 (5), 391-400, 2004 | 3258 | 2004 |
VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation HP Gerber, TH Vu, AM Ryan, J Kowalski, Z Werb, N Ferrara Nature medicine 5 (6), 623-628, 1999 | 2626 | 1999 |
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway: requirement for Flk-1/KDR … HP Gerber, A McMurtrey, J Kowalski, M Yan, BA Keyt, V Dixit, N Ferrara Journal of Biological Chemistry 273 (46), 30336-30343, 1998 | 2589 | 1998 |
HIF-1α is essential for myeloid cell-mediated inflammation T Cramer, Y Yamanishi, BE Clausen, I Förster, R Pawlinski, N Mackman, ... Cell 112 (5), 645-657, 2003 | 2452 | 2003 |
VEGF inhibition and renal thrombotic microangiopathy V Eremina, JA Jefferson, J Kowalewska, H Hochster, M Haas, J Weisstuch, ... New England Journal of Medicine 358 (11), 1129-1136, 2008 | 1723 | 2008 |
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases V Eremina, M Sood, J Haigh, A Nagy, G Lajoie, N Ferrara, HP Gerber, ... The Journal of clinical investigation 111 (5), 707-716, 2003 | 1572 | 2003 |
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells HP Gerber, V Dixit, N Ferrara Journal of biological chemistry 273 (21), 13313-13316, 1998 | 1389 | 1998 |
VEGF is required for growth and survival in neonatal mice HP Gerber, KJ Hillan, AM Ryan, J Kowalski, GA Keller, L Rangell, ... Development 126 (6), 1149-1159, 1999 | 1196 | 1999 |
Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes: Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia HP Gerber, F Condorelli, J Park, N Ferrara Journal of Biological Chemistry 272 (38), 23659-23667, 1997 | 1144 | 1997 |
Arterial thromboembolic events in patients with metastatic carcinoma treated with chemotherapy and bevacizumab FA Scappaticci, JR Skillings, SN Holden, HP Gerber, K Miller, ... Journal of the National Cancer Institute 99 (16), 1232-1239, 2007 | 1134 | 2007 |
Tumor refractoriness to anti-VEGF treatment is mediated by CD11b+Gr1+ myeloid cells F Shojaei, X Wu, AK Malik, C Zhong, ME Baldwin, S Schanz, G Fuh, ... Nature biotechnology 25 (8), 911-920, 2007 | 992 | 2007 |
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism HP Gerber, AK Malik, GP Solar, D Sherman, XH Liang, G Meng, K Hong, ... Nature 417 (6892), 954-958, 2002 | 954 | 2002 |
Vascular endothelial growth factor is essential for corpus luteum angiogenesis N Ferrara, H Chen, T Davis-Smyth, HP Gerber, TN Nguyen, D Peers, ... Nature medicine 4 (3), 336-340, 1998 | 936 | 1998 |
Vascular endothelial growth factor molecular and biological aspects N Ferrara, HP Gerber Advances in organ biology 7, 25-57, 1999 | 871 | 1999 |
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1 J LeCouter, DR Moritz, B Li, GL Phillips, XH Liang, HP Gerber, KJ Hillan, ... Science 299 (5608), 890-893, 2003 | 850 | 2003 |
Corneal avascularity is due to soluble VEGF receptor-1 BK Ambati, M Nozaki, N Singh, A Takeda, PD Jani, T Suthar, ... Nature 443 (7114), 993-997, 2006 | 841 | 2006 |
Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies HP Gerber, N Ferrara Cancer research 65 (3), 671-680, 2005 | 822 | 2005 |
Transcriptional activation modulated by homopolymeric glutamine and proline stretches HP Gerber, K Seipel, O Georgiev, M Höfferer, M Hug, S Rusconi, ... Science 263 (5148), 808-811, 1994 | 778 | 1994 |
Loss of HIF-1α in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis N Tang, L Wang, J Esko, FJ Giordano, Y Huang, HP Gerber, N Ferrara, ... Cancer cell 6 (5), 485-495, 2004 | 673 | 2004 |