The role of phosphoinositide 3-kinase lipid products in cell function LE Rameh, LC Cantley Journal of Biological Chemistry 274 (13), 8347-8350, 1999 | 1332 | 1999 |
Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation OV Vieira, RJ Botelho, L Rameh, SM Brachmann, T Matsuo, ... The Journal of cell biology 155 (1), 19-26, 2001 | 648 | 2001 |
A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains LE Rameh, A Arvidsson, KL Carraway, AD Couvillon, G Rathbun, ... Journal of Biological Chemistry 272 (35), 22059-22066, 1997 | 629 | 1997 |
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer KM Vasudevan, DA Barbie, MA Davies, R Rabinovsky, CJ McNear, ... Cancer cell 16 (1), 21-32, 2009 | 621 | 2009 |
A new pathway for synthesis of phosphatidylinositol-4, 5-bisphosphate LE Rameh, KF Tolias, BC Duckworth, LC Cantley Nature 390 (6656), 192-196, 1997 | 556 | 1997 |
Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation L Poliseno, L Salmena, L Riccardi, A Fornari, MS Song, RM Hobbs, ... Science signaling 3 (117), ra29-ra29, 2010 | 546 | 2010 |
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling C Gewinner, ZC Wang, A Richardson, J Teruya-Feldstein, ... Cancer cell 16 (2), 115-125, 2009 | 521 | 2009 |
Targeting Plasmodium PI(4)K to eliminate malaria CW McNamara, MCS Lee, CS Lim, SH Lim, J Roland, A Nagle, O Simon, ... Nature 504 (7479), 248-253, 2013 | 445 | 2013 |
Systemic elevation of PTEN induces a tumor-suppressive metabolic state I Garcia-Cao, MS Song, RM Hobbs, G Laurent, C Giorgi, VCJ De Boer, ... Cell 149 (1), 49-62, 2012 | 435 | 2012 |
The Effects of Wortmannin on Rat Skeletal Muscle: DISSOCIATION OF SIGNALING PATHWAYS FOR INSULIN-AND CONTRACTION-ACTIVATED HEXOSE TRANSPORT (∗) JI Yeh, EA Gulve, L Rameh, MJ Birnbaum Journal of Biological Chemistry 270 (5), 2107-2111, 1995 | 434 | 1995 |
Phosphatidylinositol (3, 4, 5) P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins LE Rameh, CS Chen, LC Cantley Cell 83 (5), 821-830, 1995 | 388 | 1995 |
Phosphoinositide 3-kinase regulates phospholipase Cγ-mediated calcium signaling LE Rameh, SG Rhee, K Spokes, A Kazlauskas, LC Cantley, LG Cantley Journal of Biological Chemistry 273 (37), 23750-23757, 1998 | 307 | 1998 |
SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34 GV Mallo, M Espina, AC Smith, MR Terebiznik, A Alemán, BB Finlay, ... The Journal of cell biology 182 (4), 741-752, 2008 | 245 | 2008 |
Negative regulation of Vps34 by Cdk mediated phosphorylation T Furuya, M Kim, M Lipinski, J Li, D Kim, T Lu, Y Shen, L Rameh, ... Molecular cell 38 (4), 500-511, 2010 | 205 | 2010 |
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages SB Berger, X Romero, C Ma, G Wang, WA Faubion, G Liao, E Compeer, ... Nature immunology 11 (10), 920-927, 2010 | 204 | 2010 |
Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3, 4, 5-trisphosphate JK Klarlund, LE Rameh, LC Cantley, JM Buxton, JJ Holik, C Sakelis, ... Journal of Biological Chemistry 273 (4), 1859-1862, 1998 | 199 | 1998 |
Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors BM Emerling, JB Hurov, G Poulogiannis, KS Tsukazawa, R Choo-Wing, ... Cell 155 (4), 844-857, 2013 | 189 | 2013 |
Phosphoinositide binding domains: embracing 3-phosphate DA Fruman, LE Rameh, LC Cantley Cell 97 (7), 817-820, 1999 | 185 | 1999 |
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3, 5-bisphosphate and phosphatidylinositol 5-phosphate KF Tolias, LE Rameh, H Ishihara, Y Shibasaki, J Chen, GD Prestwich, ... Journal of Biological Chemistry 273 (29), 18040-18046, 1998 | 164 | 1998 |
A novel HPLC-based approach makes possible the spatial characterization of cellular PtdIns5P and other phosphoinositides D Sarkes, LE Rameh Biochemical Journal 428 (3), 375-384, 2010 | 154 | 2010 |