Neurons derived from sporadic Alzheimer’s disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation A Ochalek, B Mihalik, HX Avci, A Chandrasekaran, A Téglási, I Bock, ... Alzheimer's research & therapy 9, 1-19, 2017 | 211 | 2017 |
Astrocyte differentiation of human pluripotent stem cells: new tools for neurological disorder research A Chandrasekaran, HX Avci, M Leist, J Kobolák, A Dinnyés Frontiers in cellular neuroscience 10, 215, 2016 | 193 | 2016 |
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells A Chandrasekaran, HX Avci, A Ochalek, LN Rösingh, K Molnár, L László, ... Stem cell research 25, 139-151, 2017 | 137 | 2017 |
Neurosphere based differentiation of human iPSC improves astrocyte differentiation S Zhou, K Szczesna, A Ochalek, J Kobolák, E Varga, C Nemes, ... Stem Cells International 2016 (1), 4937689, 2016 | 81 | 2016 |
Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges A Poon, Y Zhang, A Chandrasekaran, P Phanthong, B Schmid, ... New biotechnology 39, 190-198, 2017 | 63 | 2017 |
Glutamate-glutamine homeostasis is perturbed in neurons and astrocytes derived from patient iPSC models of frontotemporal dementia BI Aldana, Y Zhang, P Jensen, A Chandrasekaran, SK Christensen, ... Molecular Brain 13, 1-17, 2020 | 59 | 2020 |
Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism J Nagy, J Kobolak, S Berzsenyi, Z Ábrahám, HX Avci, I Bock, Z Bekes, ... Translational psychiatry 7 (7), e1179-e1179, 2017 | 46 | 2017 |
Astrocytic reactivity triggered by defective autophagy and metabolic failure causes neurotoxicity in frontotemporal dementia type 3 A Chandrasekaran, KS Dittlau, GI Corsi, H Haukedal, NT Doncheva, ... Stem cell reports 16 (11), 2736-2751, 2021 | 32 | 2021 |
Golgi fragmentation–One of the earliest organelle phenotypes in Alzheimer’s disease neurons H Haukedal, GI Corsi, VP Gadekar, NT Doncheva, S Kedia, N de Haan, ... Frontiers in neuroscience 17, 1120086, 2023 | 25 | 2023 |
Establishment of induced pluripotent stem cell (iPSC) line from a 63-year old patient with late onset Alzheimer's disease (LOAD) A Chandrasekaran, E Varga, C Nemes, Z Táncos, J Kobolák, A Dinnyés Stem Cell Research 17 (1), 78-80, 2016 | 8 | 2016 |
Neural derivates of canine induced pluripotent stem cells-like cells from a mild cognitive impairment dog A Chandrasekaran, BB Thomsen, JS Agerholm, LVF Pessôa, ... Frontiers in veterinary science 8, 725386, 2021 | 4 | 2021 |
Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3 H Haukedal, SS Lorenzen, EW Westi, GI Corsi, VP Gadekar, A McQuade, ... Brain, Behavior, and Immunity 113, 353-373, 2023 | 3 | 2023 |
Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies KS Dittlau, A Chandrasekaran, K Freude, L Van Den Bosch Bio-protocol 14 (4), 2024 | 1 | 2024 |
Generation of three isogenic gene-edited Huntington’s disease human embryonic stem cell lines with DOX-inducible NGN2 expression cassette in the AAVS1 safe locus LD Villegas, A Chandrasekaran, SAF Andersen, A Nørremølle, B Schmid, ... Stem Cell Research 77, 103408, 2024 | | 2024 |
Generation of two patient specific GABRD variants and their isogenic controls for modeling epilepsy M Kamand, R Taleb, M Wathikthinnakon, FA Mohamed, SP Ghazanfari, ... Stem Cell Research 76, 103372, 2024 | | 2024 |
IDENTIFYING THE ROLE OF DIFFERENTIALLY EXPRESSED MICRORNAS IN SCHIZOPHRENIA DURING NEURODEVELOPMENT F Mohamed, A Chandrasekaran, M Larsen, K Freude IBRO Neuroscience Reports 15, S189, 2023 | | 2023 |
EARLY PATHOLOGICAL CHANGES IN ALZHEIMER’S DISEASE MEDIATED BY ABERRANT MICROGLIA ACTIVITY M Kadlecova, H Haukedal, A Chandrasekaran, M Larsen, K Freude IBRO Neuroscience Reports 15, S182, 2023 | | 2023 |
Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology P Rivera-Sánchez, L Søndergaard, M Wathikthinnakon, HBD Magnusson, ... Stem Cell Research 71, 103193, 2023 | | 2023 |
A protein-centric view of in vitro biological model systems for schizophrenia A Chandrasekaran, P Jensen, FA Mohamed, M Lancaster, ME Benros, ... Stem Cells 39 (12), 1569-1578, 2021 | | 2021 |
Canine induced pluripotent stem cells: an in vitro approach to validate the dog as a large animal model for Alzheimer’s disease LV de Figueiredo Pessôa, A Chandrasekaran, BB Thomsen, M Berendt, ... iPSCs from Diverse Species, 77-91, 2021 | | 2021 |