Novel cephalosporin conjugates display potent and selective inhibition of imipenemase-type metallo-β-lactamases KHME Tehrani, N Wade, V Mashayekhi, NC Brüchle, W Jespers, ... Journal of Medicinal Chemistry 64 (13), 9141-9151, 2021 | 24 | 2021 |
Cephalosporin prodrug inhibitors overcome metallo‐β‐lactamase driven antibiotic resistance MJ van Haren, KHME Tehrani, I Kotsogianni, N Wade, NC Brüchle, ... Chemistry–A European Journal 27 (11), 3806-3811, 2021 | 24 | 2021 |
Small molecule carboxylates inhibit metallo-β-lactamases and resensitize carbapenem-resistant bacteria to meropenem KHME Tehrani, NC Brüchle, N Wade, V Mashayekhi, D Pesce, ... ACS Infectious Diseases 6 (6), 1366-1371, 2020 | 19 | 2020 |
Mechanistic investigations of metallo‐β‐lactamase inhibitors: strong zinc binding Is not required for potent enzyme inhibition N Wade, KHME Tehrani, NC Brüchle, MJ van Haren, V Mashayekhi, ... ChemMedChem 16 (10), 1651-1659, 2021 | 18 | 2021 |
Synthesis and Structure–Activity Studies of β-Barrel Assembly Machine Complex Inhibitor MRL-494 N Wade, CMJ Wesseling, P Innocenti, CJ Slingerland, GM Koningstein, ... ACS Infectious Diseases 8 (11), 2242-2252, 2022 | 6 | 2022 |
Search and rescue: tackling antibiotic resistance with chemistry N Wade Leiden University, 2024 | | 2024 |
Antibiotic Compounds NI Martin, E Van Groesen, KHME Tehrani, N Wade US Patent App. 17/761,376, 2023 | | 2023 |
Novel cephalosporin conjugates display potent and selective inhibition of IMP type metallo-β-lactamases K Tehrani, N Wade, V Mashayekhi, N Brüchle, W Jespers, K Voskuil, ... | | 2020 |