Osteoblast-derived WNT16 represses osteoclastogenesis and prevents cortical bone fragility fractures S Movérare-Skrtic, P Henning, X Liu, K Nagano, H Saito, AE Börjesson, ... Nature medicine 20 (11), 1279-1288, 2014 | 353 | 2014 |
Comparison of biophysical stimuli for mechano-regulation of tissue differentiation during fracture healing H Isaksson, W Wilson, CC van Donkelaar, R Huiskes, K Ito Journal of biomechanics 39 (8), 1507-1516, 2006 | 352 | 2006 |
A mechano-regulatory bone-healing model incorporating cell-phenotype specific activity H Isaksson, CC van Donkelaar, R Huiskes, K Ito Journal of theoretical biology 252 (2), 230-246, 2008 | 187 | 2008 |
Bone regeneration during distraction osteogenesis: mechano-regulation by shear strain and fluid velocity H Isaksson, O Comas, CC van Donkelaar, J Mediavilla, W Wilson, ... Journal of biomechanics 40 (9), 2002-2011, 2007 | 185 | 2007 |
Sclerostin antibody treatment enhances metaphyseal bone healing in rats F Agholme, X Li, H Isaksson, HZ Ke, P Aspenberg Journal of Bone and Mineral Research 25 (11), 2412-2418, 2010 | 178 | 2010 |
Corroboration of mechanoregulatory algorithms for tissue differentiation during fracture healing: comparison with in vivo results H Isaksson, CC van Donkelaar, R Huiskes, K Ito Journal of Orthopaedic Research 24 (5), 898-907, 2006 | 177 | 2006 |
Precision of nanoindentation protocols for measurement of viscoelasticity in cortical and trabecular bone H Isaksson, S Nagao, M MaŁkiewicz, P Julkunen, R Nowak, JS Jurvelin Journal of biomechanics 43 (12), 2410-2417, 2010 | 125 | 2010 |
Longitudinal elastic properties and porosity of cortical bone tissue vary with age in human proximal femur MKH Malo, D Rohrbach, H Isaksson, J Töyräs, JS Jurvelin, IS Tamminen, ... Bone 53 (2), 451-458, 2013 | 121 | 2013 |
Recent advances in mechanobiological modeling of bone regeneration H Isaksson Mechanics Research Communications 42, 22-31, 2012 | 118 | 2012 |
Cannabidiol, a major non‐psychotropic cannabis constituent enhances fracture healing and stimulates lysyl hydroxylase activity in osteoblasts NM Kogan, E Melamed, E Wasserman, B Raphael, A Breuer, KS Stok, ... Journal of Bone and Mineral Research 30 (10), 1905-1913, 2015 | 117 | 2015 |
Extracting accurate strain measurements in bone mechanics: A critical review of current methods L Grassi, H Isaksson Journal of the mechanical behavior of biomedical materials 50, 43-54, 2015 | 116 | 2015 |
A novel method to simulate the progression of collagen degeneration of cartilage in the knee: data from the osteoarthritis initiative ME Mononen, P Tanska, H Isaksson, RK Korhonen Scientific reports 6 (1), 21415, 2016 | 114 | 2016 |
Nano-hydroxyapatite bone substitute functionalized with bone active molecules for enhanced cranial bone regeneration AK Teotia, DB Raina, C Singh, N Sinha, H Isaksson, M Tagil, L Lidgren, ... ACS applied materials & interfaces 9 (8), 6816-6828, 2017 | 113 | 2017 |
Generation of 3D shape, density, cortical thickness and finite element mesh of proximal femur from a DXA image SP Väänänen, L Grassi, G Flivik, JS Jurvelin, H Isaksson Medical image analysis 24 (1), 125-134, 2015 | 107 | 2015 |
Experimental validation of finite element model for proximal composite femur using optical measurements L Grassi, SP Väänänen, SA Yavari, H Weinans, JS Jurvelin, AA Zadpoor, ... Journal of the mechanical behavior of biomedical materials 21, 86-94, 2013 | 100 | 2013 |
Infrared spectroscopy indicates altered bone turnover and remodeling activity in renal osteodystrophy H Isaksson, MJ Turunen, L Rieppo, S Saarakkala, IS Tamminen, J Rieppo, ... Journal of Bone and Mineral Research 25 (6), 1360-1366, 2010 | 97 | 2010 |
The masquelet induced membrane technique with BMP and a synthetic scaffold can heal a rat femoral critical size defect P Bosemark, C Perdikouri, M Pelkonen, H Isaksson, M Tägil Journal of Orthopaedic Research 33 (4), 488-495, 2015 | 94 | 2015 |
Sensitivity of tissue differentiation and bone healing predictions to tissue properties H Isaksson, CC Van Donkelaar, K Ito Journal of biomechanics 42 (5), 555-564, 2009 | 91 | 2009 |
Remodeling of fracture callus in mice is consistent with mechanical loading and bone remodeling theory H Isaksson, I Gröngröft, W Wilson, CC van Donkelaar, B van Rietbergen, ... Journal of Orthopaedic Research 27 (5), 664-672, 2009 | 89 | 2009 |
A review of the combination of experimental measurements and fibril‐reinforced modeling for investigation of articular cartilage and chondrocyte response to loading P Julkunen, W Wilson, H Isaksson, JS Jurvelin, W Herzog, RK Korhonen Computational and mathematical methods in medicine 2013 (1), 326150, 2013 | 88 | 2013 |