Post-translational proteolysis in polypeptide hormone biosynthesis K Docherty, DF Steiner Annual review of physiology 44 (1), 625-638, 1982 | 737 | 1982 |
Pancreatic duodenal homeobox–1, PDX-1, a major regulator of beta cell identity and function CM McKinnon, K Docherty Diabetologia 44, 1203-1214, 2001 | 354 | 2001 |
Missense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetes WM Macfarlane, TM Frayling, S Ellard, JC Evans, LIS Allen, MP Bulman, ... The Journal of clinical investigation 104 (9), R33-R39, 1999 | 317 | 1999 |
Glucose stimulates translocation of the homeodomain transcription factor PDX1 from the cytoplasm to the nucleus in pancreatic β-cells WM Macfarlane, CM McKinnon, ZA Felton-Edkins, H Cragg, RFL James, ... Journal of Biological Chemistry 274 (2), 1011-1016, 1999 | 276 | 1999 |
The insulin gene promoter: a simplified nomenclature M German, S Ashcroft, K Docherty, H Edlund, T Edlund, S Goodison, ... Diabetes 44 (8), 1002-1004, 1995 | 242 | 1995 |
Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic β cell AS Bernardo, CW Hay, K Docherty Molecular and cellular endocrinology 294 (1-2), 1-9, 2008 | 223 | 2008 |
The p38/reactivating kinase mitogen-activated protein kinase cascade mediates the activation of the transcription factor insulin upstream factor 1 and insulin gene … WM Macfarlane, SB Smith, RFL James, AD Clifton, YN Doza, P Cohen, ... Journal of Biological Chemistry 272 (33), 20936-20944, 1997 | 223 | 1997 |
Comparative analysis of insulin gene promoters: implications for diabetes research CW Hay, K Docherty Diabetes 55 (12), 3201-3213, 2006 | 217 | 2006 |
Nutrient regulation of insulin gene expression K Docherty, AR Clark The FASEB journal 8 (1), 20-27, 1994 | 193 | 1994 |
Positive and negative regulation of the human insulin gene by multiple trans-acting factors. DS Boam, AR Clark, K Docherty Journal of Biological Chemistry 265 (14), 8285-8296, 1990 | 185 | 1990 |
Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease. K Docherty, RJ Carroll, DF Steiner Proceedings of the National Academy of Sciences 79 (15), 4613-4617, 1982 | 182 | 1982 |
Glucose modulates the binding activity of the β-cell transcription factor IUF1 in a phosphorylation-dependent manner WM MacFarlane, ML Read, M Gilligan, I Bujalska, K Docherty Biochemical Journal 303 (2), 625-631, 1994 | 176 | 1994 |
Golgi/granule processing of peptide hormone and neuropeptide precursors: a minireview DF Steiner, K Docherty, R Carroll Journal of cellular biochemistry 24 (2), 121-130, 1984 | 172 | 1984 |
A member of the eukaryotic subtilisin family (PC3) has the enzymic properties of the type 1 proinsulin-converting endopeptidase EM Bailyes, KIJ Shennan, AJ Seal, SP Smeekens, DF Steiner, JC Hutton, ... Biochemical Journal 285 (2), 391-394, 1992 | 170 | 1992 |
Phosphorylation-dependent nucleocytoplasmic shuttling of pancreatic duodenal homeobox-1 LJ Elrick, K Docherty Diabetes 50 (10), 2244-2252, 2001 | 162 | 2001 |
C/EBPβ reprograms white 3T3-L1 preadipocytes to a brown adipocyte pattern of gene expression G Karamanlidis, A Karamitri, K Docherty, DG Hazlerigg, MA Lomax Journal of Biological Chemistry 282 (34), 24660-24669, 2007 | 139 | 2007 |
Distinctive roles of canonical and noncanonical Wnt signaling in human embryonic cardiomyocyte development S Mazzotta, C Neves, RJ Bonner, AS Bernardo, K Docherty, S Hoppler Stem cell reports 7 (4), 764-776, 2016 | 132 | 2016 |
Carboxypeptidase activity in the insulin secretory granule K Docherty, JC Hutton FEBS letters 162 (1), 137-141, 1983 | 128 | 1983 |
Negative regulation of transcription in eukaryotes. AR Clark, K Docherty Biochemical journal 296 (Pt 3), 521, 1993 | 121 | 1993 |
Relative contribution of PDX-1, MafA and E47/β2 to the regulation of the human insulin promoter HM Docherty, CW Hay, LA Ferguson, J Barrow, E Durward, K Docherty Biochemical Journal 389 (3), 813-820, 2005 | 115 | 2005 |