Substrate-targeting γ-secretase modulators TL Kukar, TB Ladd, MA Bann, PC Fraering, R Narlawar, GM Maharvi, ... Nature 453 (7197), 925-929, 2008 | 379 | 2008 |
Development of tau aggregation inhibitors for Alzheimer's disease B Bulic, M Pickhardt, B Schmidt, EM Mandelkow, H Waldmann, ... Angewandte Chemie International Edition 48 (10), 1740-1752, 2009 | 314 | 2009 |
Acute cerebrovascular disease in the young: the Stroke in Young Fabry Patients study A Rolfs, F Fazekas, U Grittner, M Dichgans, P Martus, M Holzhausen, ... Stroke 44 (2), 340-349, 2013 | 294 | 2013 |
Curcumin‐derived pyrazoles and isoxazoles: Swiss army knives or blunt tools for Alzheimer's disease? R Narlawar, M Pickhardt, S Leuchtenberger, K Baumann, S Krause, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (1), 165-172, 2008 | 209 | 2008 |
Dysfunction of somatostatin-positive interneurons associated with memory deficits in an Alzheimer’s disease model LC Schmid, M Mittag, S Poll, J Steffen, J Wagner, HR Geis, I Schwarz, ... Neuron 92 (1), 114-125, 2016 | 203 | 2016 |
A disintegrin and metalloproteinase 17 (ADAM17) mediates inflammation-induced shedding of syndecan-1 and-4 by lung epithelial cells J Pruessmeyer, C Martin, FM Hess, N Schwarz, S Schmidt, T Kogel, ... Journal of biological chemistry 285 (1), 555-564, 2010 | 203 | 2010 |
Angiotensin II receptor–independent antiinflammatory and antiaggregatory properties of losartan: role of the active metabolite EXP3179 C Krämer, J Sunkomat, J Witte, M Luchtefeld, M Walden, B Schmidt, ... Circulation research 90 (7), 770-776, 2002 | 198 | 2002 |
MAOA gene hypomethylation in panic disorder—reversibility of an epigenetic risk pattern by psychotherapy C Ziegler, J Richter, M Mahr, A Gajewska, MA Schiele, A Gehrmann, ... Translational Psychiatry 6 (4), e773-e773, 2016 | 189 | 2016 |
Small‐Molecule Inhibitors of GSK‐3: Structural Insights and Their Application to Alzheimer′ s Disease Models T Kramer, B Schmidt, F Lo Monte International journal of Alzheimer’s disease 2012 (1), 381029, 2012 | 179 | 2012 |
DOCKTITE A Highly Versatile Step-by-Step Workflow for Covalent Docking and Virtual Screening in the Molecular Operating Environment C Scholz, S Knorr, K Hamacher, B Schmidt Journal of chemical information and modeling 55 (2), 398-406, 2015 | 176 | 2015 |
Long-Term In Vivo Imaging of Fibrillar Tau in the Retina of P301S Transgenic Mice C Schön, NA Hoffmann, SM Ochs, S Burgold, S Filser, S Steinbach, ... PloS one 7 (12), e53547, 2012 | 175 | 2012 |
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites B Schmidt, B Schieffer Journal of medicinal chemistry 46 (12), 2261-2270, 2003 | 157 | 2003 |
Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of τ aggregation and toxicity in vitro and in cells M Pickhardt, G Larbig, I Khlistunova, A Coksezen, B Meyer, ... Biochemistry 46 (35), 10016-10023, 2007 | 154 | 2007 |
Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations. Evidence against a cyclic AMP-and cyclic … M Böhm, R Brückner, I Hackbarth, B Haubitz, R Linhart, W Meyer, ... Journal of Pharmacology and Experimental Therapeutics 230 (2), 483-492, 1984 | 126 | 1984 |
Amyloid plaque formation precedes dendritic spine loss T Bittner, S Burgold, MM Dorostkar, M Fuhrmann, BM Wegenast-Braun, ... Acta neuropathologica 124, 797-807, 2012 | 123 | 2012 |
An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin V Lo Sardo, C Zuccato, G Gaudenzi, B Vitali, C Ramos, M Tartari, ... Nature neuroscience 15 (5), 713-721, 2012 | 119 | 2012 |
Regulation of peroxisome proliferator–activated receptor γ activity by losartan metabolites M Schupp, LD Lee, N Frost, S Umbreen, B Schmidt, T Unger, U Kintscher Hypertension 47 (3), 586-589, 2006 | 117 | 2006 |
Design, synthesis, and biological activities of four angiotensin II receptor ligands with γ-turn mimetics replacing amino acid residues 3− 5 B Schmidt, S Lindman, W Tong, G Lindeberg, A Gogoll, Z Lai, ... Journal of medicinal chemistry 40 (6), 903-919, 1997 | 109 | 1997 |
In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks S Burgold, T Bittner, MM Dorostkar, D Kieser, M Fuhrmann, G Mitteregger, ... Acta neuropathologica 121, 327-335, 2011 | 101 | 2011 |
Soluble CD23 controls IgE synthesis and homeostasis in human B cells AM Cooper, PS Hobson, MR Jutton, MW Kao, B Drung, B Schmidt, ... The Journal of Immunology 188 (7), 3199-3207, 2012 | 99 | 2012 |