Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4 JL Jewell, E Oh, DC Thurmond American Journal of Physiology-Regulatory, Integrative and Comparative …, 2010 | 174 | 2010 |
Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion Z Wang, E Oh, DC Thurmond Journal of Biological Chemistry 282 (13), 9536-9546, 2007 | 166 | 2007 |
Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo Z Wang, E Oh, DW Clapp, J Chernoff, DC Thurmond Journal of Biological Chemistry 286 (48), 41359-41367, 2011 | 137 | 2011 |
Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4 JL Jewell, W Luo, E Oh, Z Wang, DC Thurmond Journal of Biological Chemistry 283 (16), 10716-10726, 2008 | 121 | 2008 |
Munc18c heterozygous knockout mice display increased susceptibility for severe glucose intolerance E Oh, BA Spurlin, JE Pessin, DC Thurmond Diabetes 54 (3), 638-647, 2005 | 115 | 2005 |
Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis JL Jewell, E Oh, L Ramalingam, MA Kalwat, VS Tagliabracci, L Tackett, ... Journal of Cell Biology 193 (1), 185-199, 2011 | 94 | 2011 |
Munc18-1 regulates first-phase insulin release by promoting granule docking to multiple syntaxin isoforms E Oh, MA Kalwat, MJ Kim, M Verhage, DC Thurmond Journal of Biological Chemistry 287 (31), 25821-25833, 2012 | 91 | 2012 |
Doc2β is a novel Munc18c-interacting partner and positive effector of syntaxin 4-mediated exocytosis B Ke, E Oh, DC Thurmond Journal of Biological Chemistry 282 (30), 21786-21797, 2007 | 79 | 2007 |
Munc18c depletion selectively impairs the sustained phase of insulin release E Oh, DC Thurmond Diabetes 58 (5), 1165-1174, 2009 | 64 | 2009 |
The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosis E Oh, DC Thurmond Journal of Biological Chemistry 281 (26), 17624-17634, 2006 | 64 | 2006 |
The tyrosine phosphorylation of Munc18c induces a switch in binding specificity from syntaxin 4 to Doc2β JL Jewell, E Oh, SM Bennett, SO Meroueh, DC Thurmond Journal of Biological Chemistry 283 (31), 21734-21746, 2008 | 61 | 2008 |
Cool-1/βPIX functions as a guanine nucleotide exchange factor in the cycling of Cdc42 to regulate insulin secretion EM Kepner, SM Yoder, E Oh, MA Kalwat, Z Wang, LA Quilliam, ... American Journal of Physiology-Endocrinology and Metabolism 301 (6), E1072-E1080, 2011 | 53 | 2011 |
Doc2b is a key effector of insulin secretion and skeletal muscle insulin sensitivity L Ramalingam, E Oh, SM Yoder, JT Brozinick, MA Kalwat, AJ Groffen, ... Diabetes 61 (10), 2424-2432, 2012 | 51 | 2012 |
Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates L Ramalingam, E Oh, DC Thurmond Cellular and molecular life sciences 70, 2815-2834, 2013 | 50 | 2013 |
Syntaxin 4 up-regulation increases efficiency of insulin release in pancreatic islets from humans with and without type 2 diabetes mellitus E Oh, ND Stull, RG Mirmira, DC Thurmond The Journal of Clinical Endocrinology & Metabolism 99 (5), E866-E870, 2014 | 45 | 2014 |
WNK1 is a novel regulator of Munc18c-syntaxin 4 complex formation in soluble NSF attachment protein receptor (SNARE)-mediated vesicle exocytosis E Oh, CJ Heise, JM English, MH Cobb, DC Thurmond Journal of Biological Chemistry 282 (45), 32613-32622, 2007 | 42 | 2007 |
The p21-activated kinase (PAK1) is involved in diet-induced beta cell mass expansion and survival in mice and human islets M Ahn, SM Yoder, Z Wang, E Oh, L Ramalingam, R Tunduguru, ... Diabetologia 59 (10), 2145-2155, 2016 | 39 | 2016 |
Doc2b enrichment enhances glucose homeostasis in mice via potentiation of insulin secretion and peripheral insulin sensitivity L Ramalingam, E Oh, DC Thurmond Diabetologia 57, 1476-1484, 2014 | 29 | 2014 |
DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle J Zhang, E Oh, KE Merz, A Aslamy, R Veluthakal, VA Salunkhe, M Ahn, ... Diabetologia 62, 845-859, 2019 | 22 | 2019 |
Syntaxin 4 expression in pancreatic β-cells promotes islet function and protects functional β-cell mass E Oh, M Ahn, S Afelik, TC Becker, BO Roep, DC Thurmond Diabetes 67 (12), 2626-2639, 2018 | 22 | 2018 |