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Brian Cunniff
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Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms
TL Liu, S Upadhyayula, DE Milkie, V Singh, K Wang, IA Swinburne, ...
Science 360 (6386), eaaq1392, 2018
5692018
AMPK activity regulates trafficking of mitochondria to the leading edge during cell migration and matrix invasion
B Cunniff, AJ McKenzie, NH Heintz, AK Howe
Molecular biology of the cell 27 (17), 2662-2674, 2016
2222016
Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration
MH Schuler, A Lewandowska, GD Caprio, W Skillern, S Upadhyayula, ...
Molecular biology of the cell 28 (16), 2159-2169, 2017
1532017
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis
V Anathy, E Roberson, B Cunniff, JD Nolin, S Hoffman, P Spiess, ...
Molecular and cellular biology 32 (17), 3464-3478, 2012
662012
Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells
K Newick, B Cunniff, K Preston, P Held, J Arbiser, H Pass, B Mossman, ...
PloS one 7 (6), e39404, 2012
652012
ROS production by mitochondria: function or dysfunction?
FR Palma, BN Gantner, MJ Sakiyama, C Kayzuka, S Shukla, R Lacchini, ...
Oncogene 43 (5), 295-303, 2024
552024
Mitochondrial‐targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells
B Cunniff, K Benson, J Stumpff, K Newick, P Held, D Taatjes, J Joseph, ...
Journal of cellular physiology 228 (4), 835-845, 2013
512013
Peroxiredoxin 3 levels regulate a mitochondrial redox setpoint in malignant mesothelioma cells
B Cunniff, AN Wozniak, P Sweeney, K DeCosta, NH Heintz
Redox Biology 3, 79-87, 2014
482014
Peroxiredoxins and beyond; redox systems regulating lung physiology and disease
EA Elko, B Cunniff, DJ Seward, SB Chia, R Aboushousha, ...
Antioxidants & Redox Signaling 31 (14), 1070-1091, 2019
372019
A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates
B Cunniff, GW Snider, N Fredette, RJ Hondal, NH Heintz
Analytical biochemistry 443 (1), 34-40, 2013
372013
Lung organoids: advances in generation and 3D-visualization
B Cunniff, JE Druso, JL van der Velden
Histochemistry and Cell Biology 155 (2), 301-308, 2021
362021
Resolution of oxidative stress by thioredoxin reductase: Cysteine versus selenocysteine
B Cunniff, GW Snider, N Fredette, J Stumpff, RJ Hondal, NH Heintz
Redox Biology 2, 475-484, 2014
312014
Miro1-mediated mitochondrial positioning supports subcellular redox status
H Alshaabi, N Shannon, R Gravelle, S Milczarek, T Messier, B Cunniff
Redox Biology 38, 101818, 2021
302021
Disabling mitochondrial peroxide metabolism via combinatorial targeting of peroxiredoxin 3 as an effective therapeutic approach for malignant mesothelioma
B Cunniff, K Newick, KJ Nelson, AN Wozniak, S Beuschel, B Leavitt, ...
PLoS One 10 (5), e0127310, 2015
272015
Dynamic regulation of subcellular mitochondrial position for localized metabolite levels
H Alshaabi, M Heininger, B Cunniff
The journal of biochemistry 167 (2), 109-117, 2020
142020
DRP1-mediated mitochondrial fission regulates lung epithelial response to allergen
SR Bruno, A Kumar, ZF Mark, R Chandrasekaran, E Nakada, ...
International journal of molecular sciences 22 (20), 11125, 2021
112021
Unique cellular and biochemical features of human mitochondrial peroxiredoxin 3 establish the molecular basis for its specific reaction with thiostrepton
KJ Nelson, T Messier, S Milczarek, A Saaman, S Beuschel, U Gandhi, ...
Antioxidants 10 (2), 150, 2021
92021
Direct assay of thioredoxin reductase activity
RJ Hondal, NH Heintz, B Cunniff, N Fredette, GW Snider
US Patent App. 14/460,759, 2015
62015
Mitochondrial trafficking and redox/phosphorylation signaling supporting cell migration phenotypes
N Shannon, R Gravelle, B Cunniff
Frontiers in Molecular Biosciences 9, 925755, 2022
42022
1643TiP First-in-human dose-escalation and expansion study (MITOPE) to evaluate mitochondrial PRX3 inhibition by RSO-021 in patients with mesothelioma and other advanced solid …
S Dulloo, DA Fennell, PW Szlosarek, F Thistlethwaite, S Lord, ...
Annals of Oncology 33, S1292-S1293, 2022
12022
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