Resonance Raman characterization of the peroxo and hydroperoxo intermediates in cytochrome P450 IG Denisov, PJ Mak, TM Makris, SG Sligar, JR Kincaid The Journal of Physical Chemistry A 112 (50), 13172-13179, 2008 | 107 | 2008 |
Unveiling the crucial intermediates in androgen production PJ Mak, MC Gregory, IG Denisov, SG Sligar, JR Kincaid Proceedings of the National Academy of Sciences 112 (52), 15856-15861, 2015 | 78 | 2015 |
Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry M Gregory, PJ Mak, SG Sligar, JR Kincaid Angewandte Chemie (International ed. in English) 52 (20), 5342, 2013 | 77 | 2013 |
Spectroscopic studies of the cytochrome P450 reaction mechanisms PJ Mak, IG Denisov Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1866 (1), 178-204, 2018 | 76 | 2018 |
Resonance Raman detection of the hydroperoxo intermediate in the cytochrome P450 enzymatic cycle PJ Mak, IG Denisov, D Victoria, TM Makris, T Deng, SG Sligar, JR Kincaid Journal of the American Chemical Society 129 (20), 6382-6383, 2007 | 71 | 2007 |
Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450 PJ Mak, IG Denisov, YV Grinkova, SG Sligar, JR Kincaid Journal of the American Chemical Society 133 (5), 1357-1366, 2011 | 61 | 2011 |
Resonance Raman spectroscopy of the oxygenated intermediates of human CYP19A1 implicates a compound I intermediate in the final lyase step PJ Mak, A Luthra, SG Sligar, JR Kincaid Journal of the American Chemical Society 136 (13), 4825-4828, 2014 | 60 | 2014 |
Human cytochrome CYP17A1: The structural basis for compromised lyase activity with 17-hydroxyprogesterone PJ Mak, R Duggal, IG Denisov, MC Gregory, SG Sligar, JR Kincaid Journal of the American Chemical Society 140 (23), 7324-7331, 2018 | 39 | 2018 |
Differential control of heme reactivity in alpha and beta subunits of hemoglobin: A combined Raman spectroscopic and computational study EM Jones, E Monza, G Balakrishnan, GC Blouin, PJ Mak, Q Zhu, ... Journal of the American Chemical Society 136 (29), 10325-10339, 2014 | 38 | 2014 |
Experimental documentation of the structural consequences of hydrogen-bonding interactions to the proximal cysteine of a cytochrome P450 PJ Mak, Y Yang, S Im, LA Waskell, JR Kincaid Angewandte Chemie (International ed. in English) 51 (41), 10403, 2012 | 36 | 2012 |
Resonance Raman spectroscopy reveals pH-dependent active site structural changes of lactoperoxidase compound 0 and its ferryl heme O–O bond cleavage products PJ Mak, W Thammawichai, D Wiedenhoeft, JR Kincaid Journal of the American Chemical Society 137 (1), 349-361, 2015 | 35 | 2015 |
Effects of systematic peripheral group deuteration on the low‐frequency resonance Raman spectra of myoglobin derivatives PJ Mak, E Podstawka, JR Kincaid, LM Proniewicz Biopolymers: Original Research on Biomolecules 75 (3), 217-228, 2004 | 33 | 2004 |
Defining resonance Raman spectral responses to substrate binding by cytochrome P450 from Pseudomonas putida PJ Mak, D Kaluka, ME Manyumwa, H Zhang, T Deng, JR Kincaid Biopolymers: Original Research on Biomolecules 89 (11), 1045-1053, 2008 | 30 | 2008 |
Resonance Raman studies of cytochrome P450 2B4 in its interactions with substrates and redox partners PJ Mak, SC Im, H Zhang, LA Waskell, JR Kincaid Biochemistry 47 (12), 3950-3963, 2008 | 30 | 2008 |
The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4 IG Denisov, PJ Mak, YV Grinkova, D Bastien, G Bérubé, SG Sligar, ... Journal of inorganic biochemistry 158, 77-85, 2016 | 29 | 2016 |
Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17 PJ Mak, MC Gregory, SG Sligar, JR Kincaid Biochemistry 53 (1), 90-100, 2014 | 25 | 2014 |
Resonance Raman spectroscopic studies of hydroperoxo derivatives of cobalt-substituted myoglobin PJ Mak, JR Kincaid Journal of inorganic biochemistry 102 (10), 1952-1957, 2008 | 25 | 2008 |
Probing the structure-function relationship of hemoglobin in living human red blood cells J Dybas, MJ Bokamper, KM Marzec, PJ Mak Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 239, 118530, 2020 | 24 | 2020 |
Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives F Rwere, PJ Mak, JR Kincaid Biochemistry 47 (48), 12869-12877, 2008 | 24 | 2008 |
Low frequency resonance Raman spectra of isolated α and β subunits of hemoglobin and their deuterated analogues E Podstawka, PJ Mak, JR Kincaid, LM Proniewicz Biopolymers: Original Research on Biomolecules 83 (5), 455-466, 2006 | 21 | 2006 |