The viral protein corona directs viral pathogenesis and amyloid aggregation K Ezzat, M Pernemalm, S Pålsson, TC Roberts, P Järver, A Dondalska, ... Nature communications 10 (1), 2331, 2019 | 188 | 2019 |
Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging D Gupta, X Liang, S Pavlova, OPB Wiklander, G Corso, Y Zhao, O Saher, ... Journal of extracellular vesicles 9 (1), 1800222, 2020 | 140 | 2020 |
Growth media conditions influence the secretion route and release levels of engineered extracellular vesicles JP Bost, O Saher, D Hagey, DR Mamand, X Liang, W Zheng, G Corso, ... Advanced healthcare materials 11 (5), 2101658, 2022 | 40 | 2022 |
Preparation and in vitro/in vivo evaluation of antimicrobial ocular in situ gels containing a disappearing preservative for topical treatment of bacterial conjunctivitis O Saher, DM Ghorab, NM Mursi Pharmaceutical development and technology 21 (5), 600-610, 2016 | 30 | 2016 |
Levofloxacin hemihydrate ocular semi-sponges for topical treatment of bacterial conjunctivitis: Formulation and in-vitro/in-vivo characterization O Saher, DM Ghorab, NM Mursi Journal of Drug Delivery Science and Technology 31, 22-34, 2016 | 25 | 2016 |
Novel mouse model resistant to irreversible BTK inhibitors: a tool identifying new therapeutic targets and side effects HY Estupiñán, T Bouderlique, C He, A Berglöf, D Gupta, O Saher, ... Blood Advances 4 (11), 2439-2450, 2020 | 22 | 2020 |
Novel peptide-dendrimer/lipid/oligonucleotide ternary complexes for efficient cellular uptake and improved splice-switching activity O Saher, CSJ Rocha, EM Zaghloul, OPB Wiklander, S Zamolo, M Heitz, ... European Journal of Pharmaceutics and Biopharmaceutics 132, 29-40, 2018 | 22 | 2018 |
The cellular response to extracellular vesicles is dependent on their cell source and dose DW Hagey, M Ojansivu, BR Bostancioglu, O Saher, JP Bost, ... Science advances 9 (35), eadh1168, 2023 | 21 | 2023 |
Sugar and polymer excipients enhance uptake and splice-switching activity of peptide-dendrimer/lipid/oligonucleotide formulations O Saher, T Lehto, O Gissberg, D Gupta, O Gustafsson, SEL Andaloussi, ... Pharmaceutics 11 (12), 666, 2019 | 11 | 2019 |
Oligonucleotide–Palladacycle conjugates as splice-correcting agents M Hande, O Saher, KE Lundin, CIE Smith, R Zain, T Lönnberg Molecules 24 (6), 1180, 2019 | 11 | 2019 |
Novel endosomolytic compounds enable highly potent delivery of antisense oligonucleotides JP Bost, M Ojansivu, MJ Munson, E Wesén, A Gallud, D Gupta, ... Communications Biology 5 (1), 185, 2022 | 10 | 2022 |
Lipophilic peptide dendrimers for delivery of splice-switching oligonucleotides H Daralnakhla, O Saher, S Zamolo, S Bazaz, J P. Bost, M Heitz, ... Pharmaceutics 13 (1), 116, 2021 | 7 | 2021 |
Oligonucleotides Targeting DNA Repeats Downregulate Huntingtin Gene Expression in Huntington's Patient-Derived Neural Model System T Umek, T Olsson, O Gissberg, O Saher, EM Zaghloul, KE Lundin, ... nucleic acid therapeutics 31 (6), 443-456, 2021 | 6 | 2021 |
Novel orthogonally hydrocarbon-modified cell-penetrating peptide nanoparticles mediate efficient delivery of splice-switching antisense oligonucleotides in vitro and in vivo S Bazaz, T Lehto, R Tops, O Gissberg, D Gupta, B Bestas, J Bost, ... Biomedicines 9 (8), 1046, 2021 | 6 | 2021 |
The viral protein corona directs viral pathogenesis and amyloid aggregation, Nat. Commun. 10 (2019) 2331 K Ezzat, M Pernemalm, S Palsson, TC Roberts, P Jarver, A Dondalska, ... | 4 | |
Chemical Modifications and Design Influence the Potency of Huntingtin Anti-Gene Oligonucleotides O Saher, EM Zaghloul, T Umek, DW Hagey, N Mozafari, MB Danielsen, ... nucleic acid therapeutics 33 (2), 117-131, 2023 | 3 | 2023 |
Tumor cell derived osteopontin and prostaglandin E2 synergistically promote the expansion of myeloid derived suppressor cells during the tumor immune escape phase DR Mamand, S Bazaz, DK Mohammad, O Saher, OPB Wiklander, ... International Immunopharmacology 129, 111584, 2024 | | 2024 |
Anti-gene oligonucleotides targeting Friedreichs ataxia expanded GAA: TTC repeats increase Frataxin expression N Mozafari, SIM Milagres, CSJ Rocha, CM Vargiu, F Freyberger, O Saher, ... bioRxiv, 2024.01. 25.577034, 2024 | | 2024 |
Pharmaceutical Insights into Improving Oligonucleotide Delivery and Efficacy O Saher PQDT-Global, 2021 | | 2021 |