| Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness P Van Eerdewegh, RD Little, J Dupuis, RG Del Mastro, K Falls, J Simon, ... Nature 418 (6896), 426-430, 2002 | 1592 | 2002 |
| A mutation in the LDL receptor–related protein 5 gene results in the autosomal dominant high–bone-mass trait RD Little, C Folz, SP Manning, PM Swain, SC Zhao, B Eustace, ... The American Journal of Human Genetics 70 (1), 11-19, 2002 | 1519 | 2002 |
| Isolation of single-copy human genes from a library of yeast artificial chromosome clones BH Brownstein, GA Silverman, RD Little, DT Burke, SJ Korsmeyer, ... Science 244 (4910), 1348-1351, 1989 | 480 | 1989 |
| Initiation and termination of DNA replication in human rRNA genes RD Little, THK Platt, CL Schildkraut Molecular and cellular biology, 1993 | 298 | 1993 |
| Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci JV Raelson, RD Little, A Ruether, H Fournier, B Paquin, ... Proceedings of the National Academy of Sciences 104 (37), 14747-14752, 2007 | 262 | 2007 |
| Systematic association mapping identifies NELL1 as a novel IBD disease gene A Franke, J Hampe, P Rosenstiel, C Becker, F Wagner, R Häsler, ... PloS one 2 (8), e691, 2007 | 177 | 2007 |
| Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q S Pidasheva, S Trifari, A Phillips, JA Hackney, Y Ma, A Smith, SJ Sohn, ... PloS one 6 (10), e25038, 2011 | 139 | 2011 |
| Allelic imbalance, including deletion of PTEN/MMAC1, at the Cowden disease locus on 10q22‐23, in hamartomas from patients with cowden syndrome and germline PTEN mutation DJ Marsh, PLM Dahia, V Coulon, Z Zheng, F Dorion‐Bonnet, KM Call, ... Genes, Chromosomes and Cancer 21 (1), 61-69, 1998 | 125 | 1998 |
| Genomic organization of human 5 S rDNA and sequence of one tandem repeat RD Little, DC Braaten Genomics 4 (3), 376-383, 1989 | 123 | 1989 |
| Human Xq24-Xq28: approaches to mapping with yeast artificial chromosomes. M Wada, RD Little, F Abidi, G Porta, T Labella, T Cooper, G Della Valle, ... American journal of human genetics 46 (1), 95, 1990 | 122 | 1990 |
| Initiation of latent DNA replication in the Epstein-Barr virus genome can occur at sites other than the genetically defined origin RD Little, CL Schildkraut Molecular and cellular biology, 1995 | 101 | 1995 |
| Yeast artificial chromosomes with 200-to 800-kilobase inserts of human DNA containing HLA, V kappa, 5S, and Xq24-Xq28 sequences. RD Little, G Porta, GF Carle, D Schlessinger, M D'Urso Proceedings of the National Academy of Sciences 86 (5), 1598-1602, 1989 | 99 | 1989 |
| Yeast artificial chromosomes containing human Xq24–Xq28 DNA: Library construction and representation of probe sequences FE Abidi, M Wada, RD Little, D Schlessinger Genomics 7 (3), 363-376, 1990 | 98 | 1990 |
| BATS Methods manual, version 4 AH Knap, AF Michaels, DK Steinberg, F Bahr, NR Bates, S Bell, ... US JGOFS Planning Office, 1997 | 92 | 1997 |
| Evidence that a Single Replication Fork Proceeds from Early to Late Replicating Domains in the IgH Locus in a Non–B Cell Line OV Ermakova, LH Nguyen, RD Little, C Chevillard, R Riblet, N Ashouian, ... Molecular cell 3 (3), 321-330, 1999 | 89 | 1999 |
| Locations and contexts of sequences that hybridize to poly (dG-dT).(dC-dA) in mammalian ribosomal DNAs and two X-linked genes DC Braaten, JR Thomas, RD Little, KR Dickson, I Goldberg, ... Nucleic acids research 16 (3), 865-881, 1988 | 86 | 1988 |
| High bone density due to a mutation in LDL-receptor-related protein 5 RD Little, RR Recker, ML Johnson N Engl J Med 347 (12), 943-944, 2002 | 81 | 2002 |
| Radiation down-regulates replication origin activity throughout the S phase in mammalian cells JM Larner, H Lee, PA Dijkwel, RD Little, CL Schildkraut, JL Hamlin Nucleic acids research 27 (3), 803-809, 1999 | 74 | 1999 |
| Dyad symmetry within the mouse 3'IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3). S Saleque, M Singh, RD Little, SL Giannini, JS Michaelson, BK Birshtein Journal of immunology (Baltimore, Md.: 1950) 158 (10), 4780-4787, 1997 | 74 | 1997 |
| Yeast artificial chromosomes spanning 8 megabases and 10-15 centimorgans of human cytogenetic band Xq26. RD Little, G Pilia, S Johnson, M D'Urso, D Schlessinger Proceedings of the National Academy of Sciences 89 (1), 177-181, 1992 | 73 | 1992 |
