Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis KSH Beckham, L Ciccarelli, CM Bunduc, HDT Mertens, R Ummels, ... Nature microbiology 2 (6), 1-7, 2017 | 130 | 2017 |
Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds D Wang, CE Zetterström, M Gabrielsen, KSH Beckham, JJ Tree, ... Journal of Biological Chemistry 286 (34), 29922-29931, 2011 | 109 | 2011 |
An NAD+ phosphorylase toxin triggers Mycobacterium tuberculosis cell death DM Freire, C Gutierrez, A Garza-Garcia, AD Grabowska, AJ Sala, ... Molecular cell 73 (6), 1282-1291. e8, 2019 | 68 | 2019 |
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 KSH Beckham, JPR Connolly, JM Ritchie, D Wang, JA Gawthorne, ... Molecular microbiology 93 (1), 199-211, 2014 | 54 | 2014 |
Structure of the mycobacterial ESX-5 type VII secretion system pore complex KSH Beckham, C Ritter, G Chojnowski, DS Ziemianowicz, E Mullapudi, ... Science advances 7 (26), eabg9923, 2021 | 46 | 2021 |
Express your LOV: an engineered flavoprotein as a reporter for protein expression and purification JA Gawthorne, LE Reddick, SN Akpunarlieva, KSH Beckham, JM Christie, ... Plos one 7 (12), e52962, 2012 | 40 | 2012 |
Signal regulatory protein alpha (SIRPα) regulates the homeostasis of CD103+CD11b+ DCs in the intestinal lamina propria CL Scott, TFP Zangerle Murray, KSH Beckham, G Douce, AMI Mowat European journal of immunology 44 (12), 3658-3668, 2014 | 36 | 2014 |
From screen to target: insights and approaches for the development of anti-virulence compounds KSH Beckham, AJ Roe Frontiers in Cellular and Infection Microbiology 4, 139, 2014 | 24 | 2014 |
Structural characterisation of Tpx from Yersinia pseudotuberculosis reveals insights into the binding of salicylidene acylhydrazide compounds M Gabrielsen, KSH Beckham, VA Feher, CE Zetterström, D Wang, ... PLoS One 7 (2), e32217, 2012 | 22 | 2012 |
Conserved and specialized functions of Type VII secretion systems in non-tuberculous mycobacteria M Lagune, C Petit, FV Sotomayor, MD Johansen, KSH Beckham, C Ritter, ... Microbiology 167 (7), 001054, 2021 | 17 | 2021 |
The ATPases of the mycobacterial type VII secretion system: Structural and mechanistic insights into secretion TD Crosskey, KSH Beckham, M Wilmanns Progress in Biophysics and Molecular Biology 152, 25-34, 2020 | 17 | 2020 |
Formate–nitrite transporters: Optimisation of expression, purification and analysis of prokaryotic and eukaryotic representatives KSH Beckham, JA Potter, SE Unkles Protein expression and purification 71 (2), 184-189, 2010 | 13 | 2010 |
Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis M Gabrielsen, CE Zetterström, D Wang, KSH Beckham, M Elofsson, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 10 | 2010 |
The pMy vector series: A versatile cloning platform for the recombinant production of mycobacterial proteins in Mycobacterium smegmatis KSH Beckham, S Staack, M Wilmanns, AHA Parret Protein Science 29 (12), 2528-2537, 2020 | 7 | 2020 |
Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex KSH Beckham, C Ritter, G Chojnowski, E Mullapudi, M Rettel, ... bioRxiv, 2020.11. 17.387225, 2020 | 7 | 2020 |
C25-modified rifamycin derivatives with improved activity against Mycobacterium abscessus L Paulowski, KSH Beckham, MD Johansen, L Berneking, N Van, ... PNAS nexus 1 (4), pgac130, 2022 | 6 | 2022 |
The structure of an orthorhombic crystal form of aforced reduced'thiol peroxidase reveals lattice formation aided by the presence of the affinity tag KSH Beckham, O Byron, AJ Roe, M Gabrielsen Acta Crystallographica Section F: Structural Biology and Crystallization …, 2012 | 3 | 2012 |
FolX from Pseudomonas aeruginosa is octameric in both crystal and solution M Gabrielsen, KSH Beckham, RJ Cogdell, O Byron, AJ Roe FEBS letters 586 (8), 1160-1165, 2012 | 3 | 2012 |
High-Throughput Methods for the Identification of Protein Purification Conditions Using a Cleavable Tag System M Gabrielsen, KSH Beckham, AJ Roe Methods in cell biology 112, 93-110, 2012 | 2 | 2012 |
Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved … R Zambelloni, KSH Beckham, HJ Wu, M Elofsson, R Marquez, ... Microbiology 168 (7), 001211, 2022 | 1 | 2022 |