A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress PM Bruno, Y Liu, GY Park, J Murai, CE Koch, TJ Eisen, JR Pritchard, ... Nature medicine 23 (4), 461-471, 2017 | 491 | 2017 |
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors K Birsoy, T Wang, R Possemato, OH Yilmaz, CE Koch, WW Chen, ... Nature genetics 45 (1), 104-108, 2013 | 277 | 2013 |
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains KS Gordon, T Kyung, CR Perez, PV Holec, A Ramos, AQ Zhang, ... Nature biomedical engineering 6 (7), 855-866, 2022 | 36 | 2022 |
The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina K Sukhdeo, CE Koch, TE Miller, H Zhou, M Rivera, K Yan, CL Cepko, ... Experimental eye research 119, 106-110, 2014 | 23 | 2014 |
Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening A Ramos, CE Koch, Y Liu-Lupo, RD Hellinger, T Kyung, KL Abbott, ... Nature Communications 14 (1), 8048, 2023 | 7 | 2023 |
Identification of anticancer drugs to radiosensitise BRAF-wild-type and mutant colorectal cancer R Carter, A Cheraghchi-Bashi, A Westhorpe, S Yu, Y Shanneik, E Seraia, ... Cancer Biology & Medicine 16 (2), 234, 2019 | 7 | 2019 |
CARPOOL: A library-based platform to rapidly identify next generation chimeric antigen receptors T Kyung, KS Gordon, CR Perez, PV Holec, A Ramos, AQ Zhang, Y Liu, ... bioRxiv, 2021.07. 09.450900, 2021 | 3 | 2021 |
Abstract PR-003: In vivo genome-wide CRISPR/Cas9 screens conducted in an immunocompetent mouse model of glioblastoma identify novel in vivo tumor … CE Koch, CA Whittaker, MT Hemann Cancer Research 84 (5_Supplement_1), PR-003-PR-003, 2024 | | 2024 |
Utilizing in vivo genome-wide CRISPR/Cas9 screens in immunocompetent mouse models to identify novel tumor liabilities and explore mechanisms of resistance to Chimeric Antigen … CE Koch Massachusetts Institute of Technology, 2024 | | 2024 |
Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains KS Gordon, T Kyung, CR Perez, PV Holec, A Ramos, AQ Zhang, ... Nature Biomedical Engineering 7 (4), 599-602, 2023 | | 2023 |