| Paracrine factors of human fetal MSCs inhibit liver cancer growth through reduced activation of IGF-1R/PI3K/Akt signaling Y Yulyana, IAW Ho, KC Sia, JP Newman, XY Toh, BB Endaya, JKY Chan, ... Molecular Therapy 23 (4), 746-756, 2015 | 100 | 2015 |
| Combined treatment of Nimotuzumab and rapamycin is effective against temozolomide-resistant human gliomas regardless of the EGFR mutation status DQ Chong, XY Toh, IAW Ho, KC Sia, JP Newman, Y Yulyana, WH Ng, ... BMC cancer 15, 1-13, 2015 | 47 | 2015 |
| Matrix metalloproteinase‐1‐mediated mesenchymal stem cell tumor tropism is dependent on crosstalk with stromal derived growth factor 1/C‐X‐C chemokine receptor 4 axis IAW Ho, Y Yulyana, KC Sia, JP Newman, CM Guo, KM Hui, PYP Lam The FASEB Journal 28 (10), 4359-4368, 2014 | 46 | 2014 |
| Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP5+, Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma … Y Yulyana, A Tovmasyan, IAW Ho, KC Sia, JP Newman, WH Ng, CM Guo, ... Stem cell reviews and reports 12, 140-155, 2016 | 37 | 2016 |
| An efficient and safe herpes simplex virus type 1 amplicon vector for transcriptionally targeted therapy of human hepatocellular carcinomas PYP Lam, KC Sia, JH Khong, B De Geest, KS Lim, IAW Ho, GY Wang, ... Molecular Therapy 15 (6), 1129-1136, 2007 | 32 | 2007 |
| Suicidal gene therapy in the effective control of primary human hepatocellular carcinoma as monitored by noninvasive bioimaging KC Sia, H Huynh, N Chinnasamy, KM Hui, PYP Lam Gene therapy 19 (5), 532-542, 2012 | 20 | 2012 |
| Human mesenchymal stem cells preferentially migrate toward highly oncogenic human hepatocellular carcinoma cells with activated EpCAM signaling B Endaya, SP Guan, JP Newman, H Huynh, KC Sia, ST Chong, CYL Kok, ... Oncotarget 8 (33), 54629, 2017 | 17 | 2017 |
| Correction of murine diabetic hyperglycaemia with a single systemic administration of an AAV2/8 vector containing a novel codon optimized human insulin gene G Shu Uin, N Maria, FZ Ying, L Kok Onn, S Kian Chuan, N Amit Chunilal, ... Current Gene Therapy 16 (1), 65-72, 2016 | 17 | 2016 |
| Development of a liver‐specific Tet‐off AAV8 vector for improved safety of insulin gene therapy for diabetes SU Gan, Z Fu, KC Sia, OL Kon, R Calne, KO Lee The journal of gene medicine 21 (1), e3067, 2019 | 15 | 2019 |
| The potential application of a transcriptionally regulated oncolytic herpes simplex virus for human cancer therapy L Miao, C Fraefel, KC Sia, JP Newman, SA Mohamed-Bashir, WH Ng, ... British journal of cancer 110 (1), 94-106, 2014 | 15 | 2014 |
| Hybrid herpes simplex virus/Epstein–Barr virus amplicon viral vectors confer enhanced transgene expression in primary human tumors and human bone marrow‐derived mesenchymal … KC Sia, WK Chong, IAW Ho, Y Yulyana, B Endaya, H Huynh, PYP Lam The Journal of Gene Medicine 12 (10), 848-858, 2010 | 14 | 2010 |
| Optimal purification method for Herpes-based viral vectors that confers minimal cytotoxicity for systemic route of vector administration KC Sia, GY Wang, IAW Ho, HY Khor, L Miao, KM Hui, PYP Lam Journal of virological methods 139 (2), 166-174, 2007 | 14 | 2007 |
| Immunosuppression overcomes insulin-and vector-specific immune responses that limit efficacy of AAV2/8-mediated insulin gene therapy in NOD mice A Recino, SU Gan, KC Sia, Y Sawyer, J Trendell, R Kay, FM Gribble, ... Gene Therapy 26 (1), 40-56, 2019 | 10 | 2019 |
| Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model KC Sia, H Huynh, AYF Chung, LLPJ Ooi, KH Lim, KM Hui, PYP Lam Molecular cancer therapeutics 12 (8), 1651-1664, 2013 | 10 | 2013 |
| Engineering an improved cell cycle-regulatable herpes simplex virus type 1 amplicon vector with enhanced transgene expression in proliferating cells yet attenuated activities … GY Wang, IAW Ho, KC Sia, L Miao, KM Hui, PYP Lam Human gene therapy 18 (3), 222-231, 2007 | 9 | 2007 |
| Modification of a constitutive to glucose-responsive liver-specific promoter resulted in increased efficacy of adeno-associated virus serotype 8-insulin gene therapy of … KC Sia, ZY Fu, RY Calne, AC Nathwani, KO Lee, SU Gan Cells 9 (11), 2474, 2020 | 8 | 2020 |
| Targeting human glioma cells using HSV-1 amplicon peptide display vector IAW Ho, L Miao, KC Sia, GY Wang, KM Hui, PYP Lam Gene therapy 17 (2), 250-260, 2010 | 7 | 2010 |
| First use of gene therapy to treat growth hormone resistant dwarfism in a mouse model KC Sia, SU Gan, SH Mohd Rodhi, ZY Fu, JJ Kopchick, MJ Waters, KO Lee Gene Therapy 29 (6), 346-356, 2022 | 4 | 2022 |
| Efficient AAV9 Purification Using a Single-Step AAV9 Magnetic Affinity Beads Isolation KC Sia, ZY Fu, SH Mohd Rodhi, JHY Yee, K Qu, SU Gan International Journal of Molecular Sciences 25 (15), 8342, 2024 | | 2024 |
| Restoration of normoglycemia in diabetic models via insulin gene therapy A Recino, SU Gan, KC Sia, YK Sawyer, JE Trendell, R Kay, FM Gribble, ... HUMAN GENE THERAPY 30 (2), A6-A6, 2019 | | 2019 |
