Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan, CL Tran, L Abusleme, ... Science 374 (6575), eabl5450, 2021 | 105 | 2021 |
The kallikrein-related peptidase family: Dysregulation and functions during cancer progression T Kryza, ML Silva, D Loessner, N Heuzé-Vourc'h, JA Clements Biochimie 122, 283-299, 2016 | 105 | 2016 |
Primary immunodeficiencies reveal the essential role of tissue neutrophils in periodontitis LM Silva, L Brenchley, NM Moutsopoulos Immunological reviews 287 (1), 226-235, 2019 | 89 | 2019 |
Plasmin-mediated fibrinolysis enables macrophage migration in a murine model of inflammation LM Silva, AG Lum, C Tran, MW Shaw, Z Gao, MJ Flick, NM Moutsopoulos, ... Blood, The Journal of the American Society of Hematology 134 (3), 291-303, 2019 | 43 | 2019 |
Neutrophil extracellular traps and extracellular histones potentiate IL-17 inflammation in periodontitis TS Kim, LM Silva, VI Theofilou, T Greenwell-Wild, L Li, DW Williams, ... Journal of Experimental Medicine 220 (9), 2023 | 37 | 2023 |
C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection JV Desai, D Kumar, T Freiwald, D Chauss, MD Johnson, MS Abers, ... Cell 186 (13), 2802-2822. e22, 2023 | 33 | 2023 |
Kallikrein‐related peptidase 4 induces cancer‐associated fibroblast features in prostate‐derived stromal cells T Kryza, LM Silva, N Bock, RA Fuhrman‐Luck, CR Stephens, J Gao, ... Molecular Oncology 11 (10), 1307-1329, 2017 | 27 | 2017 |
Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency LM Silva, T Stoll, T Kryza, CR Stephens, ML Hastie, HF Irving-Rodgers, ... Scientific reports 7 (1), 6789, 2017 | 26 | 2017 |
Integration of two in-depth quantitative proteomics approaches determines the kallikrein-related peptidase 7 (KLK7) degradome in ovarian cancer cell secretome LM Silva, T Kryza, T Stoll, C Hoogland, Y Dong, CR Stephens, ML Hastie, ... Molecular & Cellular Proteomics 18 (5), 818-836, 2019 | 25 | 2019 |
CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets HJ Jürgensen, LM Silva, O Krigslund, S Van Putten, DH Madsen, ... Matrix Biology Plus 1, 100003, 2019 | 24 | 2019 |
Suppression of fibrin (ogen)-driven pathologies in disease models through controlled knockdown by lipid nanoparticle delivery of siRNA LJ Juang, WS Hur, LM Silva, AW Strilchuk, B Francisco, J Leung, ... Blood, The Journal of the American Society of Hematology 139 (9), 1302-1311, 2022 | 18 | 2022 |
Proteomic and other analyses to determine the functional consequences of deregulated kallikrein‐related peptidase (KLK) expression in prostate and ovarian cancer RA Fuhrman‐Luck, ML Silva, Y Dong, H Irving‐Rodgers, T Stoll, ... PROTEOMICS–Clinical Applications 8 (5-6), 403-415, 2014 | 18 | 2014 |
The molecular function of kallikrein‐related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer T Kryza, N Bock, S Lovell, A Rockstroh, ML Lehman, A Lesner, ... Molecular oncology 14 (1), 105-128, 2020 | 17 | 2020 |
Neutrophils are gatekeepers of mucosal immunity LM Silva, TS Kim, NM Moutsopoulos Immunological reviews 314 (1), 125-141, 2023 | 10 | 2023 |
Lipid nanoparticles and siRNA targeting plasminogen provide lasting inhibition of fibrinolysis in mouse and dog models of hemophilia A AW Strilchuk, WS Hur, P Batty, Y Sang, SR Abrahams, ASM Yong, ... Science Translational Medicine 16 (735), eadh0027, 2024 | 5 | 2024 |
Plasmin-Mediated Fibrinolysis in Periodontitis Pathogenesis LM Silva, K Divaris, TH Bugge, NM Moutsopoulos Journal of Dental Research 102 (9), 972-978, 2023 | 5 | 2023 |
Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier. Science 374: eabl5450 LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan, CL Tran, L Abusleme, ... This study identifies fibrin as a critical immune regulator of oral mucosal …, 2021 | 5 | 2021 |
Imaging of anthrax intoxication in mice reveals shared and individual functions of surface receptors CMG-2 and TEM-8 in cellular toxin entry C Merritt, EM Chun, RJ Fattah, LM Silva, QQ Ma, M Moayeri, D Paliga, ... Journal of Biological Chemistry 298 (1), 2022 | 4 | 2022 |
NIH-FDA IIG TS Kim, LM Silva, VI Theofilou, T Greenwell-Wild, L Li, PI Diaz, MJ Kaplan, ... J Exp Med 220 (9), e20221751, 2023 | 3 | 2023 |
Fibrin is a critical regulator of neutrophil effector function at mucosal barrier sites LM Silva, AD Doyle, CL Tran, T Greenwell-Wild, N Dutzan, AG Lum, ... bioRxiv, 2021.01. 15.426743, 2021 | 3 | 2021 |