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Zhiheng Deng
Zhiheng Deng
在 mails.tsinghua.edu.cn 的电子邮件经过验证
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H2B Lys34 ubiquitination induces nucleosome distortion to stimulate Dot1L activity
H Ai, M Sun, A Liu, Z Sun, T Liu, L Cao, L Liang, Q Qu, Z Li, Z Deng, ...
Nature Chemical Biology 18 (9), 972-980, 2022
582022
Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains
L Lu, X Zhai, X Li, S Wang, L Zhang, L Wang, X Jin, L Liang, Z Deng, Z Li, ...
Nature Communications 13 (1), 4672, 2022
572022
Chemical synthesis of post-translationally modified H2AX reveals redundancy in interplay between histone phosphorylation, ubiquitination, and methylation on the binding of …
H Ai, GC Chu, Q Gong, ZB Tong, Z Deng, X Liu, F Yang, Z Xu, JB Li, ...
Journal of the American Chemical Society 144 (40), 18329-18337, 2022
352022
Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination
H Ai, Z Tong, Z Deng, J Tian, L Zhang, M Sun, Y Du, Z Xu, Q Shi, L Liang, ...
Chem 9 (5), 1221-1240, 2023
262023
The Bre1/Rad6 machinery: writing the central histone ubiquitin mark on H2B and beyond
ZH Deng, HS Ai, CP Lu, JB Li
Chromosome Research 28, 247-258, 2020
132020
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes
Z Tong, H Ai, Z Xu, K He, GC Chu, Q Shi, Z Deng, Q Xue, M Sun, Y Du, ...
Nature Structural & Molecular Biology 31 (2), 300-310, 2024
92024
Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A
Z Deng, H Ai, M Sun, Z Tong, Y Du, Q Qu, L Zhang, Z Xu, S Tao, Q Shi, ...
Molecular Cell 83 (17), 3080-3094. e14, 2023
82023
Structural visualization of HECT-E3 Ufd4 accepting and transferring ubiquitin to form K29/K48-branched polyubiquitination on N-degron
J Mao, H Ai, X Wu, Q Zheng, H Cai, L Liang, Z Tong, M Pan, L Liu
BioRxiv, 2023.05. 23.542033, 2023
72023
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16
H Ai, Z He, Z Deng, GC Chu, Q Shi, Z Tong, JB Li, M Pan, L Liu
Nature Structural & Molecular Biology, 1-11, 2024
12024
Capturing Snapshots of Nucleosomal H2A K13/K15 Ubiquitination Mediated by the Monomeric E3 Ligase RNF168
H Ai, Z Tong, Z Deng, Q Shi, S Tao, J Liang, M Sun, X Wei, Q Zheng, ...
bioRxiv, 2024.01. 02.573964, 2024
12024
Ubiquitin-induced RNF168 condensation promotes DNA double-strand break repair
LL Feng, SY Bie, ZH Deng, SM Bai, J Shi, CL Qin, HL Liu, JX Li, WY Chen, ...
Proceedings of the National Academy of Sciences 121 (28), e2322972121, 2024
2024
Promotion of RNF168-Mediated Nucleosomal H2A Ubiquitylation by Structurally-defined K63-Polyubiquitylated Linker Histone H1
Q Shi, Z Deng, L Zhang, Z Tong, JB Li, GC Chu, H Ai, L Liu
bioRxiv, 2024.07. 22.604500, 2024
2024
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