| Electrochemical measurement of endogenously produced nitric oxide in brain slices using Nafion/o-phenylenediamine modified carbon fiber microelectrodes NR Ferreira, A Ledo, JG Frade, GA Gerhardt, J Laranjinha, RM Barbosa Analytica Chimica Acta 535 (1-2), 1-7, 2005 | 111 | 2005 |
| Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor A Ledo, RM Barbosa, GA Gerhardt, E Cadenas, J Laranjinha Proceedings of the National Academy of Sciences 102 (48), 17483-17488, 2005 | 108 | 2005 |
| Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions A Ledo, J Frade, RM Barbosa, J Laranjinha Molecular aspects of medicine 25 (1-2), 75-89, 2004 | 93 | 2004 |
| Neurovascular-neuroenergetic coupling axis in the brain: master regulation by nitric oxide and consequences in aging and neurodegeneration CF Lourenço, A Ledo, RM Barbosa, J Laranjinha Free Radical Biology and Medicine 108, 668-682, 2017 | 91 | 2017 |
| Neurovascular uncoupling in the triple transgenic model of Alzheimer's disease: Impaired cerebral blood flow response to neuronal-derived nitric oxide signaling CF Lourenço, A Ledo, RM Barbosa, J Laranjinha Experimental neurology 291, 36-43, 2017 | 80 | 2017 |
| Nitric oxide inactivation mechanisms in the brain: role in bioenergetics and neurodegeneration RM Santos, CF Lourenço, A Ledo, RM Barbosa, J Laranjinha International Journal of Cell Biology 2012 (1), 391914, 2012 | 56 | 2012 |
| Nitric oxide signaling in the brain: translation of dynamics into respiration control and neurovascular coupling J Laranjinha, RM Santos, CF Lourenço, A Ledo, RM Barbosa Annals of the New York Academy of Sciences 1259 (1), 10-18, 2012 | 47 | 2012 |
| Neurovascular and neurometabolic derailment in aging and Alzheimer's disease CF Lourenço, A Ledo, C Dias, RM Barbosa, J Laranjinha Frontiers in aging neuroscience 7, 103, 2015 | 45 | 2015 |
| Age-dependent impairment of neurovascular and neurometabolic coupling in the hippocampus CF Lourenço, A Ledo, M Caetano, RM Barbosa, J Laranjinha Frontiers in Physiology 9, 913, 2018 | 41 | 2018 |
| Simultaneous measurements of ascorbate and glutamate in vivo in the rat brain using carbon fiber nanocomposite sensors and microbiosensor arrays NR Ferreira, A Ledo, J Laranjinha, GA Gerhardt, RM Barbosa Bioelectrochemistry 121, 142-150, 2018 | 41 | 2018 |
| Microelectrode array biosensor for high-resolution measurements of extracellular glucose in the brain CF Lourenço, A Ledo, J Laranjinha, GA Gerhardt, RM Barbosa Sensors and Actuators B: Chemical 237, 298-307, 2016 | 40 | 2016 |
| Neurometabolic and electrophysiological changes during cortical spreading depolarization: Multimodal approach based on a lactate-glucose dual microbiosensor arrays CF Lourenço, A Ledo, GA Gerhardt, J Laranjinha, RM Barbosa Scientific reports 7 (1), 6764, 2017 | 38 | 2017 |
| Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation C Dias, CF Lourenço, E Ferreiro, RM Barbosa, J Laranjinha, A Ledo Neurobiology of Aging 46, 84-95, 2016 | 38 | 2016 |
| Ceramic-based multisite platinum microelectrode arrays: morphological characteristics and electrochemical performance for extracellular oxygen measurements in brain tissue A Ledo, CF Lourenco, J Laranjinha, CMA Brett, GA Gerhardt, RM Barbosa Analytical chemistry 89 (3), 1674-1683, 2017 | 33 | 2017 |
| In vivo hydrogen peroxide diffusivity in brain tissue supports volume signaling activity A Ledo, E Fernandes, A Salvador, J Laranjinha, RM Barbosa Redox Biology 50, 102250, 2022 | 29 | 2022 |
| Dynamic and interacting profiles of⋅ NO and O2 in rat hippocampal slices A Ledo, R Barbosa, E Cadenas, J Laranjinha Free Radical Biology and Medicine 48 (8), 1044-1050, 2010 | 29 | 2010 |
| Nitric oxide monitoring in hippocampal brain slices using electrochemical methods A Ledo, RM Barbosa, J Frade, J Laranjinha Methods in enzymology 359, 111-125, 2002 | 28 | 2002 |
| Combined in vivo amperometric oximetry and electrophysiology in a single sensor: A tool for epilepsy research A Ledo, CF Lourenço, J Laranjinha, GA Gerhardt, RM Barbosa Analytical chemistry 89 (22), 12383-12390, 2017 | 27 | 2017 |
| Preparation, standardization and measurement of nitric oxide solutions RM Barbosaa, AJL Jesusb, RM Santosa, CL Pereiraa, CF Marquesa, ... Global Journal of Analytical Chemistry| Volume 2 (6), 2011 | 24 | 2011 |
| The bioactivity of neuronal-derived nitric oxide in aging and neurodegeneration: Switching signaling to degeneration A Ledo, CF Lourenço, E Cadenas, RM Barbosa, J Laranjinha Free Radical Biology and Medicine 162, 500-513, 2021 | 21 | 2021 |
João LaranjinhaProfessor, Faculty of Pharmacy and Center for Neurosciences and Cell Biology, University of Coimbra在 ci.uc.pt 的电子邮件经过验证
