Real-time observation of transcription initiation and elongation on an endogenous yeast gene DR Larson, D Zenklusen, B Wu, JA Chao, RH Singer science 332 (6028), 475-478, 2011 | 724 | 2011 |
A transgenic mouse for in vivo detection of endogenous labeled mRNA T Lionnet, K Czaplinski, X Darzacq, Y Shav-Tal, AL Wells, JA Chao, ... Nature methods 8 (2), 165-170, 2011 | 377 | 2011 |
Dual modes of RNA-silencing suppression by Flock House virus protein B2 JA Chao, JH Lee, BR Chapados, EW Debler, A Schneemann, ... Nature structural & molecular biology 12 (11), 952-957, 2005 | 359 | 2005 |
Single-molecule analysis of gene expression using two-color RNA labeling in live yeast S Hocine, P Raymond, D Zenklusen, JA Chao, RH Singer Nature methods 10 (2), 119-121, 2013 | 335 | 2013 |
An RNA biosensor for imaging the first round of translation from single cells to living animals JM Halstead, T Lionnet, JH Wilbertz, F Wippich, A Ephrussi, RH Singer, ... Science 347 (6228), 1367-1671, 2015 | 282 | 2015 |
Structural basis for the coevolution of a viral RNA–protein complex JA Chao, Y Patskovsky, SC Almo, RH Singer Nature structural & molecular biology 15 (1), 103-105, 2008 | 272 | 2008 |
Single-molecule imaging reveals translation of mRNAs localized to stress granules D Mateju, B Eichenberger, F Voigt, J Eglinger, G Roth, JA Chao Cell 183 (7), 1801-1812. e13, 2020 | 233 | 2020 |
Fluorescence fluctuation spectroscopy enables quantitative imaging of single mRNAs in living cells B Wu, JA Chao, RH Singer Biophysical journal 102 (12), 2936-2944, 2012 | 219 | 2012 |
ZBP1 recognition of β-actin zipcode induces RNA looping JA Chao, Y Patskovsky, V Patel, M Levy, SC Almo, RH Singer Genes & development 24 (2), 148-158, 2010 | 219 | 2010 |
The dynamics of mRNA turnover revealed by single-molecule imaging in single cells I Horvathova, F Voigt, AV Kotrys, Y Zhan, CG Artus-Revel, J Eglinger, ... Molecular cell 68 (3), 615-625. e9, 2017 | 195 | 2017 |
Spatial arrangement of an RNA zipcode identifies mRNAs under post-transcriptional control VL Patel, S Mitra, R Harris, AR Buxbaum, T Lionnet, M Brenowitz, M Girvin, ... Genes & development 26 (1), 43-53, 2012 | 165 | 2012 |
Single-molecule imaging of mRNA localization and regulation during the integrated stress response JH Wilbertz, F Voigt, I Horvathova, G Roth, Y Zhan, JA Chao Molecular cell 73 (5), 946-958. e7, 2019 | 148 | 2019 |
Single-mRNA counting using fluorescent in situ hybridization in budding yeast T Trcek, JA Chao, DR Larson, HY Park, D Zenklusen, SM Shenoy, ... Nature protocols 7 (2), 408-419, 2012 | 135 | 2012 |
Single-molecule quantification of translation-dependent association of mRNAs with the endoplasmic reticulum F Voigt, H Zhang, XA Cui, D Triebold, AX Liu, J Eglinger, ES Lee, JA Chao, ... Cell reports 21 (13), 3740-3753, 2017 | 87 | 2017 |
An unbiased analysis method to quantify mRNA localization reveals its correlation with cell motility HY Park, T Trcek, AL Wells, JA Chao, RH Singer Cell reports 1 (2), 179-184, 2012 | 78 | 2012 |
Joint X-ray and NMR refinement of the yeast L30e-mRNA complex JA Chao, JR Williamson Structure 12 (7), 1165-1176, 2004 | 76 | 2004 |
Dynamic visualization of transcription and RNA subcellular localization in zebrafish PD Campbell, JA Chao, RH Singer, FL Marlow Development 142 (7), 1368-1374, 2015 | 75 | 2015 |
CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma NT Ross, F Lohmann, S Carbonneau, A Fazal, WA Weihofen, S Gleim, ... Nature chemical biology 16 (1), 50-59, 2020 | 69 | 2020 |
The structural basis for RNA selectivity by the IMP family of RNA-binding proteins J Biswas, VL Patel, V Bhaskar, JA Chao, RH Singer, C Eliscovich Nature Communications 10 (1), 4440, 2019 | 44 | 2019 |
Imaging translation in single cells using fluorescent microscopy JA Chao, YJ Yoon, RH Singer Cold Spring Harbor Perspectives in Biology 4 (11), a012310, 2012 | 42 | 2012 |