Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair H Yu, H Pak, I Hammond-Martel, M Ghram, A Rodrigue, S Daou, ... Proceedings of the National Academy of Sciences 111 (1), 285-290, 2014 | 403 | 2014 |
Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T-but not from B-cell lineage acute … J Hebert, JM Cayuela, J Berkeley, F Sigaux | 380 | 1994 |
A key role for EZH2 and associated genes in mouse and human adult T-cell acute leukemia C Simon, J Chagraoui, J Krosl, P Gendron, B Wilhelm, S Lemieux, ... Genes & development 26 (7), 651-656, 2012 | 319 | 2012 |
A mouse PRMT1 null allele defines an essential role for arginine methylation in genome maintenance and cell proliferation Z Yu, T Chen, J Hébert, E Li, S Richard Molecular and cellular biology, 2009 | 232 | 2009 |
Mubritinib targets the electron transport chain complex I and reveals the landscape of OXPHOS dependency in acute myeloid leukemia I Baccelli, Y Gareau, B Lehnertz, S Gingras, JF Spinella, S Corneau, ... Cancer cell 36 (1), 84-99. e8, 2019 | 207 | 2019 |
GPR56 identifies primary human acute myeloid leukemia cells with high repopulating potential in vivo C Pabst, A Bergeron, VP Lavallée, J Yeh, P Gendron, GL Norddahl, ... Blood, The Journal of the American Society of Hematology 127 (16), 2018-2027, 2016 | 195 | 2016 |
The transcriptomic landscape and directed chemical interrogation of MLL-rearranged acute myeloid leukemias VP Lavallée, I Baccelli, J Krosl, B Wilhelm, F Barabé, P Gendron, ... Nature genetics 47 (9), 1030-1037, 2015 | 167 | 2015 |
Identification of small molecules that support human leukemia stem cell activity ex vivo C Pabst, J Krosl, I Fares, G Boucher, R Ruel, A Marinier, S Lemieux, ... Nature methods 11 (4), 436-442, 2014 | 158 | 2014 |
The methyltransferase G9a regulates HoxA9-dependent transcription in AML B Lehnertz, C Pabst, L Su, M Miller, F Liu, L Yi, R Zhang, J Krosl, E Yung, ... Genes & development 28 (4), 317-327, 2014 | 155 | 2014 |
AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia F Zhou, Y Liu, C Rohde, C Pauli, D Gerloff, M Köhn, D Misiak, N Bäumer, ... Nature cell biology 19 (7), 844-855, 2017 | 152 | 2017 |
Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1, 2, 4-thiadiazolidine, 3, 5 dione (TDZD-8) ML Guzman, X Li, CA Corbett, RM Rossi, T Bushnell, JL Liesveld, ... Blood, The Journal of the American Society of Hematology 110 (13), 4436-4444, 2007 | 147 | 2007 |
Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes M Tremblay, CS Tremblay, S Herblot, PD Aplan, J Hébert, C Perreault, ... Genes & development 24 (11), 1093-1105, 2010 | 136 | 2010 |
UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia A Benyoucef, CG Palii, C Wang, CJ Porter, A Chu, F Dai, V Tremblay, ... Genes & development 30 (5), 508-521, 2016 | 128 | 2016 |
Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance M Buscarlet, V Krasteva, L Ho, C Simon, J Hébert, B Wilhelm, ... Blood, The Journal of the American Society of Hematology 123 (11), 1720-1728, 2014 | 119 | 2014 |
Expression of immunoproteasome genes is regulated by cell-intrinsic and–extrinsic factors in human cancers A Rouette, A Trofimov, D Haberl, G Boucher, VP Lavallée, G D’Angelo, ... Scientific reports 6 (1), 34019, 2016 | 106 | 2016 |
A role for GPx3 in activity of normal and leukemia stem cells O Herault, KJ Hope, E Deneault, N Mayotte, J Chagraoui, BT Wilhelm, ... Journal of Experimental Medicine 209 (5), 895-901, 2012 | 106 | 2012 |
Breast carcinoma–associated fibroblasts rarely contain p53 mutations or chromosomal aberrations AN Hosein, M Wu, SL Arcand, S Lavallée, J Hébert, PN Tonin, M Basik Cancer research 70 (14), 5770-5777, 2010 | 103 | 2010 |
The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation Z Yu, G Vogel, Y Coulombe, D Dubeau, E Spehalski, J Hébert, ... Cell research 22 (2), 305-320, 2012 | 99 | 2012 |
Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification J Hέbert, JM Cayuela, MT Daniel, R Berger, F Sigaux Blood 84 (7), 2291-2296, 1994 | 98 | 1994 |
Allogeneic transplantation for multiple myeloma: further evidence for a GVHD-associated graft-versus-myeloma effect R Le Blanc, S Montminy-Metivier, R Belanger, L Busque, D Fish, DC Roy, ... Bone marrow transplantation 28 (9), 841-848, 2001 | 88 | 2001 |