Congenital leptin deficiency is associated with severe early-onset obesity in humans CT Montague, IS Farooqi, JP Whitehead, MA Soos, H Rau, NJ Wareham, ... Nature 387 (6636), 903-907, 1997 | 4126 | 1997 |
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index EK Speliotes, CJ Willer, SI Berndt, KL Monda, G Thorleifsson, AU Jackson, ... Nature genetics 42 (11), 937-948, 2010 | 3565 | 2010 |
Effects of recombinant leptin therapy in a child with congenital leptin deficiency IS Farooqi, SA Jebb, G Langmack, E Lawrence, CH Cheetham, ... New England Journal of Medicine 341 (12), 879-884, 1999 | 2492 | 1999 |
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation CJ Willer, EK Speliotes, RJF Loos, S Li, CM Lindgren, IM Heid, SI Berndt, ... Nature genetics 41 (1), 25-34, 2009 | 2078 | 2009 |
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene IS Farooqi, JM Keogh, GSH Yeo, EJ Lank, T Cheetham, S O'Rahilly New England Journal of Medicine 348 (12), 1085-1095, 2003 | 2053 | 2003 |
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency IS Farooqi, G Matarese, GM Lord, JM Keogh, E Lawrence, C Agwu, ... The Journal of clinical investigation 110 (8), 1093-1103, 2002 | 2044 | 2002 |
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase T Gerken, CA Girard, YCL Tung, CJ Webby, V Saudek, KS Hewitson, ... Science 318 (5855), 1469-1472, 2007 | 1815 | 2007 |
Common variants near MC4R are associated with fat mass, weight and risk of obesity RJF Loos, CM Lindgren, S Li, E Wheeler, JH Zhao, I Prokopenko, ... Nature genetics 40 (6), 768-775, 2008 | 1581 | 2008 |
A frameshift mutation in MC4R associated with dominantly inherited human obesity GSH Yeo, IS Farooqi, S Aminian, DJ Halsall, RG Stanhope, S O'Rahilly Nature genetics 20 (2), 111-112, 1998 | 1405 | 1998 |
Genetics of body-weight regulation GS Barsh, IS Farooqi, S O'Rahilly Nature 404 (6778), 644-651, 2000 | 1235 | 2000 |
Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency IS Farooqi, GSH Yeo, JM Keogh, S Aminian, SA Jebb, G Butler, ... The Journal of clinical investigation 106 (2), 271-279, 2000 | 1008 | 2000 |
Clinical and molecular genetic spectrum of congenital deficiency of the leptin receptor IS Farooqi, T Wangensteen, S Collins, W Kimber, G Matarese, JM Keogh, ... New England Journal of Medicine 356 (3), 237-247, 2007 | 911 | 2007 |
Genetics of obesity in humans IS Farooqi, S O’Rahilly Endocrine reviews 27 (7), 710-718, 2006 | 836 | 2006 |
The hormonal control of food intake AP Coll, IS Farooqi, S O'Rahilly Cell 129 (2), 251-262, 2007 | 790 | 2007 |
Leptin regulates striatal regions and human eating behavior IS Farooqi, E Bullmore, J Keogh, J Gillard, S O'Rahilly, PC Fletcher Science 317 (5843), 1355-1355, 2007 | 724 | 2007 |
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay GSH Yeo, CCC Hung, J Rochford, J Keogh, J Gray, S Sivaramakrishnan, ... Nature neuroscience 7 (11), 1187-1189, 2004 | 671 | 2004 |
Large, rare chromosomal deletions associated with severe early-onset obesity EG Bochukova, NI Huang, J Keogh, E Henning, C Purmann, K Blaszczyk, ... Nature 463 (7281), 666-670, 2010 | 667 | 2010 |
Obesity associated genetic variation in FTO is associated with diminished satiety J Wardle, S Carnell, CMA Haworth, IS Farooqi, S O'Rahilly, R Plomin The Journal of Clinical Endocrinology & Metabolism 93 (9), 3640-3643, 2008 | 655 | 2008 |
Monogenic obesity in humans IS Farooqi, S O'Rahilly Annu. Rev. Med. 56, 443-458, 2005 | 622 | 2005 |
Obesity and the brain: how convincing is the addiction model? H Ziauddeen, IS Farooqi, PC Fletcher EUROPEAN NEUROPSYCHOPHARMACOLOGY 23, S156-S156, 2013 | 611 | 2013 |