| Design of freeze-drying processes for pharmaceuticals: practical advice X Tang, MJ Pikal Pharmaceutical research 21, 191-200, 2004 | 1240 | 2004 |
| Rational design of stable lyophilized protein formulations: some practical advice JF Carpenter, MJ Pikal, BS Chang, TW Randolph Pharmaceutical research 14 (8), 969, 1997 | 1025 | 1997 |
| Freeze-drying of proteins. Part II: Formulation selection MJ Pikal BioPharm 3 (9), 26-30, 1990 | 644* | 1990 |
| Mechanism of protein stabilization by sugars during freeze-drying and storage: native structure preservation, specific interaction, and/or immobilization in a glassy matrix? LL Chang, D Shepherd, J Sun, D Ouellette, KL Grant, XC Tang, MJ Pikal Journal of pharmaceutical sciences 94 (7), 1427-1444, 2005 | 520 | 2005 |
| Protein stability during freezing: separation of stresses and mechanisms of protein stabilization BS Bhatnagar, RH Bogner, MJ Pikal Pharmaceutical development and technology 12 (5), 505-523, 2007 | 516 | 2007 |
| Role of thermodynamic, molecular, and kinetic factors in crystallization from the amorphous state C Bhugra, MJ Pikal Journal of pharmaceutical sciences 97 (4), 1329-1349, 2008 | 496 | 2008 |
| Mass and heat transfer in vial freeze‐drying of pharmaceuticals: Role of the vial MJ Pikal, ML Roy, S Shah Journal of pharmaceutical sciences 73 (9), 1224-1237, 1984 | 440 | 1984 |
| Solubility advantage of amorphous pharmaceuticals: I. A thermodynamic analysis SB Murdande, MJ Pikal, RM Shanker, RH Bogner Journal of pharmaceutical sciences 99 (3), 1254-1264, 2010 | 431 | 2010 |
| The collapse temperature in freeze drying: Dependence on measurement methodology and rate of water removal from the glassy phase MJ Pikal, S Shah International Journal of Pharmaceutics 62 (2-3), 165-186, 1990 | 403 | 1990 |
| Characterization of the time scales of molecular motion in pharmaceutically important glasses SL Shamblin, X Tang, L Chang, BC Hancock, MJ Pikal The Journal of Physical Chemistry B 103 (20), 4113-4121, 1999 | 402 | 1999 |
| The role of electroosmotic flow in transdermal iontophoresis MJ Pikal Advanced drug delivery reviews 46 (1-3), 281-305, 2001 | 390 | 2001 |
| The effects of formulation variables on the stability of freeze-dried human growth hormone MJ Pikal, KM Dellerman, ML Roy, RM Riggin Pharmaceutical research 8, 427-436, 1991 | 389 | 1991 |
| Mechanisms of protein stabilization in the solid state LL Chang, MJ Pikal Journal of pharmaceutical sciences 98 (9), 2886-2908, 2009 | 387 | 2009 |
| Freeze-drying of proteins. Part I: process design MJ Pikal BioPharm 3 (8), 18-27, 1990 | 356 | 1990 |
| The secondary drying stage of freeze drying: drying kinetics as a function of temperature and chamber pressure MJ Pikal, S Shah, ML Roy, R Putman International journal of pharmaceutics 60 (3), 203-207, 1990 | 355 | 1990 |
| Quantitative crystallinity determinations for β-lactam antibiotics by solution calorimetry: Correlations with stability MJ Pikal, AL Lukes, JE Lang, K Gaines Journal of pharmaceutical sciences 67 (6), 767-773, 1978 | 348 | 1978 |
| Determination of end point of primary drying in freeze-drying process control SM Patel, T Doen, MJ Pikal Aaps Pharmscitech 11, 73-84, 2010 | 337 | 2010 |
| Use of laboratory data in freeze drying process design: heat and mass transfer coefficients and the computer simulation of freeze drying MJ Pikal PDA Journal of Pharmaceutical Science and Technology 39 (3), 115-139, 1985 | 325 | 1985 |
| Heat and mass transfer scale-up issues during freeze drying: II. Control and characterization of the degree of supercooling S Rambhatla, R Ramot, C Bhugra, MJ Pikal Aaps Pharmscitech 5, 54-62, 2004 | 300 | 2004 |
| Apparent Molal Volumes of Some Aqueous Rare Earth Chloride and Nitrate Solutions at 25°1 FH Spedding, MJ Pikal, BO Ayers The Journal of Physical Chemistry 70 (8), 2440-2449, 1966 | 297 | 1966 |
Robin BognerUniversity of Connecticut在 uconn.edu 的电子邮件经过验证
