| Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration S Ayyadevara, A Ganne, M Balasubramaniam, RJ Shmookler Reis Metabolic Brain Disease 37 (1), 147-152, 2022 | 28 | 2022 |
| Glial fibrillary acidic protein: a biomarker and drug target for alzheimer’s disease A Ganne, M Balasubramaniam, WST Griffin, RJ Shmookler Reis, ... Pharmaceutics 14 (7), 1354, 2022 | 23 | 2022 |
| “Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation RJ Shmookler Reis, R Atluri, M Balasubramaniam, J Johnson, A Ganne, ... Aging Cell 20 (5), e13326, 2021 | 21 | 2021 |
| A novel microtubule-binding drug attenuates and reverses protein aggregation in animal models of Alzheimer’s Disease S Kakraba, S Ayyadevara, NR Penthala, M Balasubramaniam, A Ganne, ... Frontiers in Molecular Neuroscience 12, 310, 2019 | 18 | 2019 |
| Aggregate interactome based on protein cross-linking interfaces predicts drug targets to limit aggregation in neurodegenerative diseases M Balasubramaniam, S Ayyadevara, A Ganne, S Kakraba, NR Penthala, ... Iscience 20, 248-264, 2019 | 14 | 2019 |
| Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease' S Ayyadevara, A Ganne, RD Hendrix, M Balasubramaniam, RJS Reis, ... Journal of neuroscience methods 319, 40-46, 2019 | 11 | 2019 |
| In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration A Ganne, M Balasubramaniam, H Ayyadevara, L Kiaei, ... Scientific Reports 13 (1), 2096, 2023 | 7 | 2023 |
| Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation A Ganne, M Balasubramaniam, S Ayyadevara, RJ Shmookler Reis Frontiers in Aging Neuroscience 14, 938117, 2022 | 6 | 2022 |
| Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase M Balasubramaniam, RJS Reis, S Ayyadevara, X Wang, A Ganne, ... Mechanisms of Ageing and Development 166, 55-63, 2017 | 5 | 2017 |
| Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain N Mainali, X Li, X Wang, M Balasubramaniam, A Ganne, R Kore, ... Molecular and Cellular Biochemistry, 1-13, 2023 | 4 | 2023 |
| Aggregate interactome based on protein cross-linking interfaces predicts drug targets to limit aggregation in neurodegenerative diseases. iScience 20, 248–264 M Balasubramaniam, S Ayyadevara, A Ganne, S Kakraba, NR Penthala, ... | 4 | 2019 |
| Protein homeostasis in the aged and diseased heart N Mainali, S Ayyadevara, A Ganne, RJS Reis, JL Mehta The journal of cardiovascular aging 3 (2), 2023 | 3 | 2023 |
| Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets M Balasubramaniam, A Ganne, N Mainali, S Pahal, S Ayyadevara, ... Iscience 27 (1), 2024 | | 2024 |
| Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer’s disease by targeted small molecules M Balasubramaniam, J Narasimhappagari, L Liu, A Ganne, S Ayyadevara, ... Communications Biology 7 (1), 60, 2024 | | 2024 |
| Ezetimibe Lowers Risk of Alzheimer’s and Related Dementias over Sevenfold, Reducing Aggregation in Model Systems by Inhibiting 14-3-3G:: Hexokinase Interaction A Ganne, N Mainali, M Balasubramaniam, R Atluri, S Pahal, JJ Asante, ... Aging biology 2, 20240028, 2024 | | 2024 |
| Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases A Ganne University of Arkansas at Little Rock, 2021 | | 2021 |
| Ezetimibe lowers risk of Alzheimer’s and Related Dementias over 7-fold, reducing aggregation in model systems by inhibiting 14-3-3G:: hexokinase interaction A Ganne, N Mainali, M Balasubramaniam, R Atluri, S Pahal, J Asante, ... | | |
Robert J. Shmookler ReisProfessor, University of Arkansas for Medical Sciences在 uams.edu 的电子邮件经过验证
