Therapeutic anticoagulation with heparin in noncritically ill patients with Covid-19 ATTACC, ACTIV-4a, and REMAP-CAP Investigators New England Journal of Medicine 385 (9), 790-802, 2021 | 1043 | 2021 |
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation JH Finigan, SM Dudek, PA Singleton, ET Chiang, JR Jacobson, SM Camp, ... Journal of Biological Chemistry 280 (17), 17286-17293, 2005 | 452 | 2005 |
Simvastatin attenuates vascular leak and inflammation in murine inflammatory lung injury JR Jacobson, JW Barnard, DN Grigoryev, SF Ma, RM Tuder, JGN Garcia American Journal of Physiology-Lung Cellular and Molecular Physiology 288 (6 …, 2005 | 342 | 2005 |
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase SM Dudek, JR Jacobson, ET Chiang, KG Birukov, P Wang, X Zhan, ... Journal of Biological Chemistry 279 (23), 24692-24700, 2004 | 334 | 2004 |
Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch KG Birukov, JR Jacobson, AA Flores, SQ Ye, AA Birukova, AD Verin, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 285 (4 …, 2003 | 329 | 2003 |
Prostaglandins PGE2 and PGI2 promote endothelial barrier enhancement via PKA-and Epac1/Rap1-dependent Rac activation AA Birukova, T Zagranichnaya, P Fu, E Alekseeva, W Chen, JR Jacobson, ... Experimental cell research 313 (11), 2504-2520, 2007 | 311 | 2007 |
Differential effects of sphingosine 1–phosphate receptors on airway and vascular barrier function in the murine lung S Sammani, L Moreno-Vinasco, T Mirzapoiazova, PA Singleton, ... American journal of respiratory cell and molecular biology 43 (4), 394-402, 2010 | 201 | 2010 |
Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin JR Jacobson, SM Dudek, KG Birukov, SQ Ye, DN Grigoryev, RE Girgis, ... American journal of respiratory cell and molecular biology 30 (5), 662-670, 2004 | 188 | 2004 |
Sphingosine-1–phosphate, FTY720, and Sphingosine-1–phosphate receptors in the pathobiology of acute lung injury V Natarajan, SM Dudek, JR Jacobson, L Moreno-Vinasco, LS Huang, ... American journal of respiratory cell and molecular biology 49 (1), 6-17, 2013 | 156 | 2013 |
Essential role of pre–B-cell colony enhancing factor in ventilator-induced lung injury SB Hong, Y Huang, L Moreno-Vinasco, S Sammani, J Moitra, JW Barnard, ... American journal of respiratory and critical care medicine 178 (6), 605-617, 2008 | 156 | 2008 |
Endothelial cell barrier protection by simvastatin: GTPase regulation and NADPH oxidase inhibition W Chen, S Pendyala, V Natarajan, JGN Garcia, JR Jacobson American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (4 …, 2008 | 121 | 2008 |
Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin JR Jacobson, SM Dudek, PA Singleton, IA Kolosova, AD Verin, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 291 (2 …, 2006 | 114 | 2006 |
Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement X Sun, Y Shikata, L Wang, K Ohmori, N Watanabe, J Wada, K Shikata, ... Microvascular research 77 (3), 304-313, 2009 | 111 | 2009 |
Sphingosine-1–phosphate receptor–3 is a novel biomarker in acute lung injury X Sun, PA Singleton, E Letsiou, J Zhao, P Belvitch, S Sammani, ... American journal of respiratory cell and molecular biology 47 (5), 628-636, 2012 | 102 | 2012 |
Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation … PV Usatyuk, P Fu, V Mohan, Y Epshtein, JR Jacobson, ... Journal of Biological Chemistry 289 (19), 13476-13491, 2014 | 92 | 2014 |
Imatinib attenuates inflammation and vascular leak in a clinically relevant two-hit model of acute lung injury AN Rizzo, S Sammani, AE Esquinca, JR Jacobson, JGN Garcia, E Letsiou, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 …, 2015 | 88 | 2015 |
Endothelial cell signaling and ventilator-induced lung injury: molecular mechanisms, genomic analyses, and therapeutic targets T Wang, C Gross, AA Desai, E Zemskov, X Wu, AN Garcia, JR Jacobson, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (4 …, 2017 | 82 | 2017 |
Regulation of hyperoxia-induced NADPH oxidase activation in human lung endothelial cells by the actin cytoskeleton and cortactin PV Usatyuk, LH Romer, D He, NL Parinandi, ME Kleinberg, S Zhan, ... Journal of Biological Chemistry 282 (32), 23284-23295, 2007 | 79 | 2007 |
Novel therapies for microvascular permeability in sepsis JR Jacobson, JG N Garcia Current drug targets 8 (4), 509-514, 2007 | 76 | 2007 |
Simvastatin attenuates radiation-induced murine lung injury and dysregulated lung gene expression B Mathew, Y Huang, JR Jacobson, E Berdyshev, LM Gerhold, T Wang, ... American journal of respiratory cell and molecular biology 44 (3), 415-422, 2011 | 75 | 2011 |