GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death L Sborgi, S Rühl, E Mulvihill, J Pipercevic, R Heilig, H Stahlberg, ... The EMBO Journal 35 (16), 1766-1778, 2016 | 1011 | 2016 |
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles S Hiller, RG Garces, TJ Malia, VY Orekhov, M Colombini, G Wagner Science 321 (5893), 1206-1210, 2008 | 761 | 2008 |
A new antibiotic selectively kills Gram-negative pathogens Y Imai, KJ Meyer, A Iinishi, Q Favre-Godal, R Green, S Manuse, M Caboni, ... Nature 576 (7787), 459-464, 2019 | 574 | 2019 |
Germline NLRP1 Mutations Cause Skin Inflammatory and Cancer Susceptibility Syndromes via Inflammasome Activation FL Zhong, O Mamaï, L Sborgi, L Boussofara, R Hopkins, K Robinson, ... Cell 167 (1), 187-202. e17, 2016 | 398 | 2016 |
ASC filament formation serves as a signal amplification mechanism for inflammasomes MS Dick, L Sborgi, S Rühl, S Hiller, P Broz Nature communications 7 (1), 11929, 2016 | 362 | 2016 |
The Gasdermin‐D pore acts as a conduit for IL‐1β secretion in mice R Heilig, MS Dick, L Sborgi, E Meunier, S Hiller, P Broz European journal of immunology 48 (4), 584-592, 2018 | 351 | 2018 |
Automated projection spectroscopy (APSY) S Hiller, F Fiorito, K Wüthrich, G Wider Proceedings of the National Academy of Sciences of the United States of …, 2005 | 287 | 2005 |
Chimeric peptidomimetic antibiotics against Gram-negative bacteria A Luther, M Urfer, M Zahn, M Müller, SY Wang, M Mondal, A Vitale, ... Nature 576 (7787), 452-458, 2019 | 265 | 2019 |
Mechanism of membrane pore formation by human gasdermin‐D E Mulvihill, L Sborgi, SA Mari, M Pfreundschuh, S Hiller, DJ Müller The EMBO journal 37 (14), e98321, 2018 | 240 | 2018 |
Regulation of α-synuclein by chaperones in mammalian cells BM Burmann, JA Gerez, I Matečko-Burmann, S Campioni, P Kumari, ... Nature 577 (7788), 127-132, 2020 | 206 | 2020 |
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs T Raschle, S Hiller, TY Yu, AJ Rice, T Walz, G Wagner Journal of the American Chemical Society 131 (49), 17777-17779, 2009 | 206 | 2009 |
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains C Suzuki, RG Garces, KA Edmonds, S Hiller, SG Hyberts, A Marintchev, ... Proceedings of the National Academy of Sciences 105 (9), 3274-3279, 2008 | 204 | 2008 |
Cyclic di-GMP acts as a cell cycle oscillator to drive chromosome replication C Lori, S Ozaki, S Steiner, R Böhm, S Abel, BN Dubey, T Schirmer, ... Nature 523 (7559), 236-239, 2015 | 201 | 2015 |
A Proton‐Detected 4D Solid‐State NMR Experiment for Protein Structure Determination M Huber, S Hiller, P Schanda, M Ernst, A Böckmann, R Verel, BH Meier ChemPhysChem 12 (5), 915-918, 2011 | 189 | 2011 |
Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy L Sborgi, F Ravotti, VP Dandey, MS Dick, A Mazur, S Reckel, M Chami, ... Proceedings of the National Academy of Sciences 112 (43), 13237-13242, 2015 | 168 | 2015 |
NMR structure of the apoptosis-and inflammation-related NALP1 pyrin domain S Hiller, A Kohl, F Fiorito, T Herrmann, G Wider, J Tschopp, MG Grütter, ... Structure 11 (10), 1199-1205, 2003 | 155 | 2003 |
Conformation and dynamics of the periplasmic membrane-protein–chaperone complexes OmpX–Skp and tOmpA–Skp BM Burmann, C Wang, S Hiller Nature Structural and Molecular Biology 20 (11), 1265, 2013 | 154 | 2013 |
HP1(Swi6) Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts C Keller, R Adaixo, R Stunnenberg, KJ Woolcock, S Hiller, M Bühler Molecular Cell, 2012 | 154 | 2012 |
The antibiotic darobactin mimics a β-strand to inhibit outer membrane insertase H Kaur, RP Jakob, JK Marzinek, R Green, Y Imai, JR Bolla, E Agustoni, ... Nature 593 (7857), 125-129, 2021 | 146 | 2021 |
The 3D structures of VDAC represent a native conformation S Hiller, J Abramson, C Mannella, G Wagner, K Zeth Trends in biochemical sciences 35 (9), 514-521, 2010 | 144 | 2010 |