Immunity, inflammation, and cancer SI Grivennikov, FR Greten, M Karin Cell 140 (6), 883-899, 2010 | 12150 | 2010 |
NF-κB: linking inflammation and immunity to cancer development and progression M Karin, FR Greten Nature reviews immunology 5 (10), 749-759, 2005 | 3811 | 2005 |
NF-κB in cancer: from innocent bystander to major culprit M Karin, Y Cao, FR Greten, ZW Li Nature reviews cancer 2 (4), 301-310, 2002 | 3392 | 2002 |
IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer FR Greten, L Eckmann, TF Greten, JM Park, ZW Li, LJ Egan, MF Kagnoff, ... Cell 118 (3), 285-296, 2004 | 3249 | 2004 |
Inflammation and cancer: triggers, mechanisms, and consequences FR Greten, SI Grivennikov Immunity 51 (1), 27-41, 2019 | 2631 | 2019 |
A framework for advancing our understanding of cancer-associated fibroblasts E Sahai, I Astsaturov, E Cukierman, DG DeNardo, M Egeblad, RM Evans, ... Nature Reviews Cancer 20 (3), 174-186, 2020 | 2581 | 2020 |
IKK-β links inflammation to obesity-induced insulin resistance MC Arkan, AL Hevener, FR Greten, S Maeda, ZW Li, JM Long, ... Nature medicine 11 (2), 191-198, 2005 | 2357 | 2005 |
Activation by IKKα of a second, evolutionary conserved, NF-κB signaling pathway U Senftleben, Y Cao, G Xiao, FR Greten, G Krähn, G Bonizzi, Y Chen, ... Science 293 (5534), 1495-1499, 2001 | 2004 | 2001 |
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties S Schwitalla, AA Fingerle, P Cammareri, T Nebelsiek, SI Göktuna, ... Cell 152 (1), 25-38, 2013 | 1160 | 2013 |
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis J Bollrath, TJ Phesse, VA von Burstin, T Putoczki, M Bennecke, ... Cancer cell 15 (2), 91-102, 2009 | 1094 | 2009 |
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ... The Journal of clinical investigation 124 (4), 1853-1867, 2014 | 782 | 2014 |
NF-κB is a negative regulator of IL-1β secretion as revealed by genetic and pharmacological inhibition of IKKβ FR Greten, MC Arkan, J Bollrath, LC Hsu, J Goode, C Miething, ... Cell 130 (5), 918-931, 2007 | 758 | 2007 |
Epithelial-cell-intrinsic IKK-β expression regulates intestinal immune homeostasis C Zaph, AE Troy, BC Taylor, LD Berman-Booty, KJ Guild, Y Du, EA Yost, ... Nature 446 (7135), 552-556, 2007 | 638 | 2007 |
The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion LW Chen, L Egan, ZW Li, FR Greten, MF Kagnoff, M Karin Nature medicine 9 (5), 575-581, 2003 | 634 | 2003 |
Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition JM Park, FR Greten, ZW Li, M Karin Science 297 (5589), 2048-2051, 2002 | 633 | 2002 |
IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development Y Cao, G Bonizzi, TN Seagroves, FR Greten, R Johnson, EV Schmidt, ... Cell 107 (6), 763-775, 2001 | 604 | 2001 |
The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer FR Greten, M Karin Cancer letters 206 (2), 193-199, 2004 | 552 | 2004 |
IKK/NF‐κB and STAT3 pathways: central signalling hubs in inflammation‐mediated tumour promotion and metastasis J Bollrath, FR Greten EMBO reports 10 (12), 1314-1319, 2009 | 479 | 2009 |
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity MD Schulz, Ç Atay, J Heringer, FK Romrig, S Schwitalla, B Aydin, ... Nature 514 (7523), 508-512, 2014 | 473 | 2014 |
Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically TL Putoczki, S Thiem, A Loving, RA Busuttil, NJ Wilson, PK Ziegler, ... Cancer cell 24 (2), 257-271, 2013 | 428 | 2013 |