SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis M Ohashi, F Liu, Y Hai, M Chen, M Tang, Z Yang, M Sato, K Watanabe, ... Nature 549 (7673), 502-506, 2017 | 168 | 2017 |
Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase M Chen, N Al-Lami, M Janvier, EL D’Antonio, JA Faraldos, DE Cane, ... Biochemistry 52 (32), 5441-5453, 2013 | 75 | 2013 |
Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase M Chen, WKW Chou, T Toyomasu, DE Cane, DW Christianson ACS chemical biology 11, 889-899, 2016 | 70 | 2016 |
Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases TA Pemberton, M Chen, GG Harris, WKW Chou, L Duan, M Köksal, ... Biochemistry 56 (14), 2010-2023, 2017 | 69 | 2017 |
Genome Mining of Alkaloidal Terpenoids from a Hybrid Terpene and Nonribosomal Peptide Biosynthetic Pathway DA Yee, TB Kakule, W Cheng, M Chen, CTY Chong, Y Hai, LF Hang, ... Journal of the American Chemical Society 142 (2), 710-714, 2019 | 49 | 2019 |
Genome mining and biosynthesis of a polyketide from a biofertilizer fungus that can facilitate reductive iron assimilation in plant M Chen, Q Liu, SS Gao, AE Young, SE Jacobsen, Y Tang Proceedings of the National Academy of Sciences of the United States of America, 2019 | 49 | 2019 |
Discovery and Biocatalytic Application of a PLP-Dependent Amino Acid γ-Substitution Enzyme that Catalyzes CC Bond Formation M Chen, CT Liu, Y Tang Journal of the American Chemical Society, 2020 | 44 | 2020 |
Biosynthesis of Mycotoxin Fusaric Acid and Application of a PLP-Dependent Enzyme for Chemoenzymatic Synthesis of Substituted l-Pipecolic Acids Y Hai, M Chen, A Huang, Y Tang Journal of the American Chemical Society 142 (46), 19668-19677, 2020 | 40 | 2020 |
Mechanism of germacradien-4-ol synthase controlled water capture DJ Grundy, M Chen, V Gonzalez, S Leoni, DJ Miller, DW Christianson, ... Biochemistry, 2016 | 39 | 2016 |
Harzianic Acid from Trichoderma afroharzianum Is a Natural Product Inhibitor of Acetohydroxyacid Synthase L Xie, X Zang, W Cheng, Z Zhang, J Zhou, M Chen, Y Tang Journal of the American Chemical Society, 2021 | 36 | 2021 |
Multi-domain terpenoid cyclase architecture and prospects for proximity in bifunctional catalysis M Chen, GG Harris, TA Pemberton, DW Christianson Current Opinion in Structural Biology 41, 27-37, 2016 | 35 | 2016 |
Genome mining for unknown–unknown natural products DA Yee, K Niwa, B Perlatti, M Chen, Y Li, Y Tang Nature chemical biology 19 (5), 633-640, 2023 | 34 | 2023 |
Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase M Chen, WKW Chou, N Al-Lami, JA Faraldos, RK Allemann, DE Cane, ... Biochemistry 55 (20), 2864-2874, 2016 | 26 | 2016 |
High-Titer Production of Olivetolic Acid and Analogs in Engineered Fungal Host Using a Nonplant Biosynthetic Pathway IC Okorafor, M Chen, Y Tang ACS synthetic biology 10 (9), 2159-2166, 2021 | 21 | 2021 |
Genome mining of cryptic tetronate natural products from a PKS-NRPS encoding gene cluster in Trichoderma harzianum t-22 Y Zhu, J Wang, P Mou, Y Yan, M Chen, Y Tang Organic & Biomolecular Chemistry 19 (9), 1985-1990, 2021 | 20 | 2021 |
Biosynthesis of Terpenoid–Pyrrolobenzoxazine Hybrid Natural Product CJ‐12662 W Cheng, M Chen, M Ohashi, Y Tang Angewandte Chemie 134 (12), e202116928, 2022 | 12 | 2022 |
Flow-injection with enhanced evaporative light scattering detector detection and quantification of human serum albumin using gold nanoparticles T Wang, M Chen, C Niu, N Liu, L Wang, B Sun, W Hua, J Ouyang Analytical Methods 7 (7), 3185-3192, 2015 | 8 | 2015 |
Unleashing the Power of Biocatalysts M Chen ChemBioChem 22 (2), 317-318, 2021 | | 2021 |
Biosynthetic platform for the production of olivetolic avid and analogues of olivetolic acid Y Tang, M Chen, I Okorafor WO Patent WO2021142393A1, 2021 | | 2021 |
Structure and function of fusicoccadiene synthase, a bifunctional diterpene synthase with an alpha-alpha fold M Chen, D Christianson ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |