Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP–1B: In vitro, in silico, and in vivo approaches JJ Ramírez-Espinosa, MY Rios, S López-Martínez, F López-Vallejo, ... European journal of medicinal chemistry 46 (6), 2243-2251, 2011 | 147 | 2011 |
Chrysin induces antidiabetic, antidyslipidemic and anti-inflammatory effects in athymic nude diabetic mice JJ Ramírez-Espinosa, J Saldaña-Ríos, S García-Jiménez, ... Molecules 23 (1), 67, 2017 | 71 | 2017 |
Discovery of Thiazolidine‐2,4‐Dione/Biphenylcarbonitrile Hybrid as Dual PPAR α/γ Modulator with Antidiabetic Effect: In vitro, In Silico and In Vivo Approaches S Hidalgo‐Figueroa, JJ Ramírez‐Espinosa, S Estrada‐Soto, ... Chemical biology & drug design 81 (4), 474-483, 2013 | 63 | 2013 |
Synthesis, hypoglycemic activity and molecular modeling studies of pyrazole-3-carbohydrazides designed by a CoMFA model E Hernández-Vázquez, R Aguayo-Ortiz, JJ Ramírez-Espinosa, ... European journal of medicinal chemistry 69, 10-21, 2013 | 52 | 2013 |
Synthesis of oleanolic acid derivatives: In vitro, in vivo and in silico studies for PTP-1B inhibition JJ Ramírez-Espinosa, MY Rios, P Paoli, V Flores-Morales, G Camici, ... European Journal of Medicinal Chemistry 87, 316-327, 2014 | 45 | 2014 |
Synthesis of 2-{2-[(α/β-naphthalen-1-ylsulfonyl) amino]-1, 3-thiazol-4-yl} acetamides with 11β-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities G Navarrete-Vázquez, MG Morales-Vilchis, S Estrada-Soto, ... European Journal of Medicinal Chemistry 74, 179-186, 2014 | 39 | 2014 |
Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies R Guzmán‐Ávila, V Flores‐Morales, P Paoli, G Camici, ... Drug Development Research 79 (2), 70-80, 2018 | 36 | 2018 |
Synthesis and molecular docking of N′-arylidene-5-(4-chlorophenyl)-1-(3, 4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents E Hernández-Vázquez, S Salgado-Barrera, JJ Ramírez-Espinosa, ... Bioorganic & medicinal chemistry 24 (10), 2298-2306, 2016 | 36 | 2016 |
Synthesis, in vitro and in silico studies of a PPARγ and GLUT-4 modulator with hypoglycemic effect G Navarrete-Vázquez, H Torres-Gómez, S Hidalgo-Figueroa, ... Bioorganic & medicinal chemistry letters 24 (18), 4575-4579, 2014 | 33 | 2014 |
Synthesis and evaluation of thiazolidine-2, 4-dione/benzazole derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B): Antihyperglycemic activity with molecular … S Hidalgo-Figueroa, S Estrada-Soto, JJ Ramírez-Espinosa, P Paoli, ... Biomedicine & Pharmacotherapy 107, 1302-1310, 2018 | 32 | 2018 |
Antihyperglycemic and sub-chronic antidiabetic actions of morolic and moronic acids, in vitro and in silico inhibition of 11β-HSD 1 JJ Ramírez-Espinosa, S García-Jiménez, MY Rios, JL Medina-Franco, ... Phytomedicine 20 (7), 571-576, 2013 | 32 | 2013 |
1, 5-Diarylpyrazole and vanillin hybrids: Synthesis, biological activity and DFT studies E Hernández-Vázquez, R Castañeda-Arriaga, JJ Ramírez-Espinosa, ... European journal of medicinal chemistry 100, 106-118, 2015 | 31 | 2015 |
In vitro and in silico PTP-1B inhibition and in vivo antidiabetic activity of semisynthetic moronic acid derivatives L Cerón-Romero, P Paoli, G Camici, V Flores-Morales, MY Rios, ... Bioorganic & Medicinal Chemistry Letters 26 (8), 2018-2022, 2016 | 26 | 2016 |
Vasorelaxant effect of Valeriana edulis ssp. procera (Valerianaceae) and its mode of action as calcium channel blocker S Estrada-Soto, J Rivera-Leyva, JJ Ramírez-Espinosa, P Castillo-España, ... Journal of Pharmacy and Pharmacology 62 (9), 1167-1174, 2010 | 26 | 2010 |
Synthesis and In Vitro AMPK Activation of Cycloalkyl/Alkarylbiguanides with Robust In Vivo Antihyperglycemic Action E Gutierrez-Lara, C Martínez-Conde, E Rosales-Ortega, ... Journal of Chemistry 2017 (1), 1212609, 2017 | 11 | 2017 |
Synthesis, in vitro, in silico and in vivo hypoglycemic and lipid-lowering effects of 4-benzyloxy-5-benzylidene-1, 3-thiazolidine-2, 4-diones mediated by dual PPAR α/γ modulation JL Madrigal-Angulo, C Ménez-Guerrero, S Estrada-Soto, ... Bioorganic & Medicinal Chemistry Letters 70, 128804, 2022 | 8 | 2022 |
Synthesis of 2-{2-[(a/b-naphthalen-yl} acetamides with 11b-hydroxysteroid dehydrogenase inhibition and in combo antidiabetic activities q G Navarrete-Vázquez, MG Morales-Vilchis, S Estrada-Soto, ... European Journal of Medicinal Chemistry 74 (17), 9e186, 2014 | 2 | 2014 |
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTPe1B JJ Ramirez-Espinosa, M Yolanda Rios, S Lopez-Martinez, ... vitro, in silico, 2243-2251, 0 | 2 | |
Día del farmacéutico JJ Ramirez Espinosa Instituto de Ciencias Biomédicas, 2022 | | 2022 |
Research Article Synthesis and In Vitro AMPK Activation of Cycloalkyl/Alkarylbiguanides with Robust In Vivo Antihyperglycemic Action E Gutierrez-Lara, C Martínez-Conde, E Rosales-Ortega, ... | | 2017 |