The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012 | 2288 | 2012 |
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma RD Morin, M Mendez-Lago, AJ Mungall, R Goya, KL Mungall, RD Corbett, ... Nature 476 (7360), 298-303, 2011 | 1881 | 2011 |
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells RD Morin, MD O’Connor, M Griffith, F Kuchenbauer, A Delaney, ... Genome research 18 (4), 610-621, 2008 | 1353 | 2008 |
Genomic landscape of non-small cell lung cancer in smokers and never-smokers R Govindan, L Ding, M Griffith, J Subramanian, ND Dees, KL Kanchi, ... Cell 150 (6), 1121-1134, 2012 | 1339 | 2012 |
De novo assembly and analysis of RNA-seq data G Robertson, J Schein, R Chiu, R Corbett, M Field, SD Jackman, ... Nature methods 7 (11), 909-912, 2010 | 1193 | 2010 |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). DS Gerhard, L Wagner, EA Feingold, CM Shenmen, LH Grouse, ... Genome research 14 (10B), 2121-2127, 2004 | 814 | 2004 |
DGIdb 3.0: a redesign and expansion of the drug–gene interaction database KC Cotto, AH Wagner, YY Feng, S Kiwala, AC Coffman, G Spies, ... Nucleic acids research 46 (D1), D1068-D1073, 2018 | 772 | 2018 |
deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data A McPherson, F Hormozdiari, A Zayed, R Giuliany, G Ha, MGF Sun, ... PLoS computational biology 7 (5), e1001138, 2011 | 616 | 2011 |
Integration of the Drug–Gene Interaction Database (DGIdb 4.0) with open crowdsource efforts SL Freshour, S Kiwala, KC Cotto, AC Coffman, JF McMichael, JJ Song, ... Nucleic acids research 49 (D1), D1144-D1151, 2021 | 589 | 2021 |
Convergent loss of PTEN leads to clinical resistance to a PI (3) Kα inhibitor D Juric, P Castel, M Griffith, OL Griffith, HH Won, H Ellis, SH Ebbesen, ... Nature 518 (7538), 240-244, 2015 | 582 | 2015 |
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 546 | 2017 |
DGIdb: mining the druggable genome M Griffith, OL Griffith, AC Coffman, JV Weible, JF McMichael, NC Spies, ... Nature methods 10 (12), 1209-1210, 2013 | 513 | 2013 |
SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution CA Miller, BS White, ND Dees, M Griffith, JS Welch, OL Griffith, R Vij, ... PLoS computational biology 10 (8), e1003665, 2014 | 491 | 2014 |
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ... Cancer cell 25 (3), 379-392, 2014 | 433 | 2014 |
DGIdb 2.0: mining clinically relevant drug–gene interactions AH Wagner, AC Coffman, BJ Ainscough, NC Spies, ZL Skidmore, ... Nucleic acids research 44 (D1), D1036-D1044, 2016 | 391 | 2016 |
Alternative expression analysis by RNA sequencing M Griffith, OL Griffith, J Mwenifumbo, R Goya, AS Morrissy, RD Morin, ... Nature methods 7 (10), 843-847, 2010 | 387 | 2010 |
pVAC-Seq: A genome-guided in silico approach to identifying tumor neoantigens J Hundal, BM Carreno, AA Petti, GP Linette, OL Griffith, ER Mardis, ... Genome medicine 8, 1-11, 2016 | 384 | 2016 |
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 381 | 2015 |
Modeling precision treatment of breast cancer A Daemen, OL Griffith, LM Heiser, NJ Wang, OM Enache, Z Sanborn, ... Genome biology 14, 1-14, 2013 | 330 | 2013 |
Mutant U2AF1 expression alters hematopoiesis and pre-mRNA splicing in vivo CL Shirai, JN Ley, BS White, S Kim, J Tibbitts, J Shao, M Ndonwi, ... Cancer cell 27 (5), 631-643, 2015 | 327 | 2015 |