Stabilization of G-quadruplex DNA by highly selective ligands via click chemistry AD Moorhouse, AM Santos, M Gunaratnam, M Moore, S Neidle, JE Moses Journal of the American Chemical Society 128 (50), 15972-15973, 2006 | 265 | 2006 |
Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation M Fritzsche, RA Fernandes, VT Chang, H Colin-York, MP Clausen, ... Science advances 3 (6), e1603032, 2017 | 166 | 2017 |
Immune checkpoints as therapeutic targets in autoimmunity C Paluch, AM Santos, C Anzilotti, RJ Cornall, SJ Davis Frontiers in immunology 9, 2306, 2018 | 121 | 2018 |
CD6 attenuates early and late signaling events, setting thresholds for T‐cell activation MI Oliveira, CM Gonçalves, M Pinto, S Fabre, AM Santos, SF Lee, ... European journal of immunology 42 (1), 195-205, 2012 | 92 | 2012 |
A cell topography-based mechanism for ligand discrimination by the T cell receptor RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, ... Proceedings of the National Academy of Sciences 116 (28), 14002-14010, 2019 | 74 | 2019 |
Capturing resting T cells: the perils of PLL AM Santos, A Ponjavic, M Fritzsche, RA Fernandes, JB de la Serna, ... Nature immunology 19 (3), 203-205, 2018 | 73 | 2018 |
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions P Jönsson, JH Southcombe, AM Santos, J Huo, RA Fernandes, J McColl, ... Proceedings of the National Academy of Sciences 113 (20), 5682-5687, 2016 | 68 | 2016 |
Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC L Sušac, MT Vuong, C Thomas, S von Bülow, C O’Brien-Ball, AM Santos, ... Cell 185 (17), 3201-3213. e19, 2022 | 58 | 2022 |
Coreceptors and TCR signaling–the strong and the weak of it AM Mørch, Š Bálint, AM Santos, SJ Davis, ML Dustin Frontiers in cell and developmental biology 8, 597627, 2020 | 56 | 2020 |
Membrane ultrastructure and T cell activation J Pettmann, AM Santos, O Dushek, SJ Davis Frontiers in immunology 9, 2152, 2018 | 56 | 2018 |
A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase M Bamberger, AM Santos, CM Gonçalves, MI Oliveira, JR James, ... Journal of Biological Chemistry 286 (35), 30324-30336, 2011 | 51 | 2011 |
Three-dimensional super-resolution in eukaryotic cells using the double-helix point spread function AR Carr, A Ponjavic, S Basu, J McColl, AM Santos, S Davis, ED Laue, ... Biophysical journal 112 (7), 1444-1454, 2017 | 48 | 2017 |
Reconstitution of immune cell interactions in free-standing membranes E Jenkins, AM Santos, C O'Brien-Ball, JH Felce, MJ Wilcock, D Hatherley, ... Journal of cell science 132 (4), jcs219709, 2019 | 44 | 2019 |
Single-molecule light-sheet imaging of suspended T cells A Ponjavic, J McColl, AR Carr, AM Santos, K Kulenkampff, A Lippert, ... Biophysical Journal 114 (9), 2200-2211, 2018 | 43 | 2018 |
T cell activation regulates CD6 alternative splicing by transcription dynamics and SRSF1 VG da Glória, M Martins de Araújo, A Mafalda Santos, R Leal, ... The Journal of Immunology 193 (1), 391-399, 2014 | 34 | 2014 |
vLUME: 3D virtual reality for single-molecule localization microscopy A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, LM Needham, ... Nature methods 17 (11), 1097-1099, 2020 | 29 | 2020 |
Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells I Urbancic, L Schiffelers, E Jenkins, W Gong, AM Santos, F Schneider, ... FEBS letters 595 (16), 2127-2146, 2021 | 27 | 2021 |
The scavenger receptor SSc5D physically interacts with bacteria through the SRCR-containing N-terminal domain C Bessa Pereira, M Bocková, RF Santos, AM Santos, M Martins de Araújo, ... Frontiers in Immunology 7, 416, 2016 | 27 | 2016 |
Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling KY Chen, E Jenkins, M Körbel, A Ponjavic, AH Lippert, AM Santos, ... Proceedings of the National Academy of Sciences 118 (39), e2024250118, 2021 | 23 | 2021 |
Dimensions and interactions of large T-cell surface proteins V Junghans, AM Santos, Y Lui, SJ Davis, P Jönsson Frontiers in immunology 9, 2215, 2018 | 23 | 2018 |