| A molecular mechanism for direct sirtuin activation by resveratrol M Gertz, GTT Nguyen, F Fischer, B Suenkel, C Schlicker, B Fränzel, ... PloS one 7 (11), e49761, 2012 | 422 | 2012 |
| Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism M Gertz, F Fischer, GTT Nguyen, M Lakshminarasimhan, M Schutkowski, ... Proceedings of the National Academy of Sciences 110 (30), E2772-E2781, 2013 | 342 | 2013 |
| Structure-based development of a receptor activator of nuclear factor-κB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis HM Ta, GTT Nguyen, HM Jin, J Choi, H Park, N Kim, HY Hwang, KK Kim Proceedings of the National Academy of Sciences 107 (47), 20281-20286, 2010 | 94 | 2010 |
| Crystal structures of Sirt3 complexes with 4′-bromo-resveratrol reveal binding sites and inhibition mechanism GTT Nguyen, M Gertz, C Steegborn Chemistry & biology 20 (11), 1375-1385, 2013 | 84 | 2013 |
| Chemical probing of the human sirtuin 5 active site reveals its substrate acyl specificity and peptide‐based inhibitors C Roessler, T Nowak, M Pannek, M Gertz, GTT Nguyen, M Scharfe, I Born, ... Angewandte Chemie 126 (40), 10904-10908, 2014 | 77 | 2014 |
| Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism GTT Nguyen, S Schaefer, M Gertz, M Weyand, C Steegborn Acta Crystallographica Section D: Biological Crystallography 69 (8), 1423-1432, 2013 | 72 | 2013 |
| High-throughput proteomics and in vitro functional characterization of the 26 medically most important elapids and vipers from sub-Saharan Africa GTT Nguyen, C O'Brien, Y Wouters, L Seneci, A Gallissà-Calzado, ... GigaScience 11, giac121, 2022 | 29 | 2022 |
| Chalcone-based Selective Inhibitors of a C4 Plant Key Enzyme as Novel Potential Herbicides GTT Nguyen, G Erlenkamp, O Jäck, A Küberl, M Bott, F Fiorani, H Gohlke, ... Scientific reports 6 (1), 27333, 2016 | 20 | 2016 |
| Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Giang Thi Tuyet Nguyen, Aleksi Sutinen, Arne Raasakka, Gopinath Muruganandam ... Front. Mol. Biosci. 7 (631232), 2021 | 11 | 2021 |
| A comparative study of protein structure prediction tools for challenging targets: Snake venom toxins K Kalogeropoulos, MF Bohn, DE Jenkins, J Ledergerber, CV Sørensen, ... Toxicon, 107559, 2024 | 8 | 2024 |
| Structural insights into Charcot–Marie–Tooth disease‐linked mutations in human GDAP1 A Sutinen, GTT Nguyen, A Raasakka, G Muruganandam, R Loris, ... FEBS open bio 12 (7), 1306-1324, 2022 | 8 | 2022 |
| In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model M Benard-Valle, Y Wouters, A Ljungars, GTT Nguyen, S Ahmadi, ... Nature Communications 15 (1), 4310, 2024 | 7 | 2024 |
| Pyrazolidine‐3,5‐dione‐based inhibitors of phosphoenolpyruvate carboxylase as a new class of potential C4 plant herbicides M Dick, G Erlenkamp, GTT Nguyen, K Förster, G Groth, H Gohlke FEBS letters 591 (20), 3369-3377, 2017 | 4 | 2017 |
| Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability A Sutinen, D Paffenholz, GTT Nguyen, S Ruskamo, AE Torda, P Kursula Plos one 18 (4), e0284532, 2023 | 3 | 2023 |
| Erratum: Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights Into Ligand Binding and Clustering of Disease Mutations GTT Nguyen, A Sutinen, A Raasakka, G Muruganandam, R Loris, ... Frontiers in Molecular Biosciences 9, 2022 | 1 | 2022 |
| Structure of the complete dimeric human GDAP1 core domain provides insights into ligand binding and clustering of disease mutations GTT Nguyen, A Sutinen, A Raasakka, G Muruganandam, R Loris, ... bioRxiv, 2020 | | 2020 |
| Structure-based development of a receptor activator of nuclear factor-κB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis HM Ta, GTT Nguyen, HM Jin, J Choi, H Park, N Kim, HY Hwang, KK Kim | | 2015 |
| Regulation of Mitochondrial Sirtuins Sirt3 and Sirt5 by Small Molecules GTT Nguyen | | 2014 |
