| Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2 C Demetriades, N Doumpas, AA Teleman Cell 156 (4), 786-799, 2014 | 434 | 2014 |
| Lysosomal recruitment of TSC2 is a universal response to cellular stress C Demetriades, M Plescher, AA Teleman Nature communications 7 (1), 10662, 2016 | 172 | 2016 |
| G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling MT Prentzell, U Rehbein, MC Sandoval, AS De Meulemeester, ... Cell 184 (3), 655-674. e27, 2021 | 80 | 2021 |
| Genomic analysis reveals a novel nuclear factor-κB (NF-κB)-binding site in Alu-repetitive elements A Antonaki, C Demetriades, A Polyzos, A Banos, G Vatsellas, MD Lavigne, ... Journal of Biological Chemistry 286 (44), 38768-38782, 2011 | 67 | 2011 |
| CycD/Cdk4 and discontinuities in Dpp signaling activate TORC1 in the Drosophila wing disc J Romero-Pozuelo, C Demetriades, P Schroeder, AA Teleman Developmental cell 42 (4), 376-387. e5, 2017 | 65 | 2017 |
| The multifaceted role of nutrient sensing and mTORC1 signaling in physiology and aging SA Fernandes, C Demetriades Frontiers in Aging 2, 38, 2021 | 53 | 2021 |
| An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress J Nüchel, M Tauber, JL Nolte, M Mörgelin, C Türk, B Eckes, ... Molecular cell 81 (16), 3275-3293. e12, 2021 | 46 | 2021 |
| Distinct amino acid residues may be involved in coactivator and ligand interactions in hepatocyte nuclear factor-4α P Iordanidou, E Aggelidou, C Demetriades, M Hadzopoulou-Cladaras Journal of Biological Chemistry 280 (23), 21810-21819, 2005 | 46 | 2005 |
| A Rag GTPase dimer code defines the regulation of mTORC1 by amino acids P Gollwitzer, N Grützmacher, S Wilhelm, D Kümmel, C Demetriades Nature Cell Biology, 2022 | 36 | 2022 |
| TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation K Fitzian, A Brückner, L Brohée, R Zech, C Antoni, S Kiontke, R Gasper, ... Molecular cell 81 (13), 2705-2721. e8, 2021 | 34 | 2021 |
| TSC2 mediates hyperosmotic stress-induced inactivation of mTORC1 M Plescher, AA Teleman, C Demetriades Scientific reports 5 (1), 13828, 2015 | 31 | 2015 |
| The LMP1 promoter can be transactivated directly by NF-κB C Demetriades, G Mosialos Journal of virology 83 (10), 5269-5277, 2009 | 31 | 2009 |
| eIF 4A inactivates TORC 1 in response to amino acid starvation FF Tsokanos, MA Albert, C Demetriades, K Spirohn, M Boutros, ... The EMBO journal 35 (10), 1058-1076, 2016 | 29 | 2016 |
| mTORC1 activity negatively regulates human hair follicle growth and pigmentation T Suzuki, J Chéret, FD Scala, A Akhundlu, J Gherardini, DL Demetrius, ... EMBO reports, e56574, 2023 | 13 | 2023 |
| Decreased spliceosome fidelity and egl-8 intron retention inhibit mTORC1 signaling to promote longevity W Huang, C Kew, S Fernandes, A Löhrke, L Han, C Demetriades, ... Nature Aging, 2022 | 8 | 2022 |
| Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor R Nicastro, L Brohée, J Alba, J Nüchel, G Figlia, S Kipschull, P Gollwitzer, ... Nature Cell Biology 25 (9), 1303-1318, 2023 | 7 | 2023 |
| Functional characterization of hepatocyte nuclear factor‐4α dimerization interface mutants E Aggelidou, P Iordanidou, C Demetriades, O Piltsi, ... The FEBS journal 273 (9), 1948-1958, 2006 | 6 | 2006 |
| Unbiased evaluation of rapamycin's specificity as an mTOR inhibitor F Artoni, N Grützmacher, C Demetriades Aging Cell 22 (8), e13888, 2023 | 4 | 2023 |
| Codependencies of mTORC1 signaling and endolysosomal actin structures A Priya, S Antoine-Bally, AS Macé, P Monteiro, V Sabatet, D Remy, ... Science Advances 9 (37), eadd9084, 2023 | 1 | 2023 |
| 518 Nutrient and stress sensing as novel physiological regulator of human hair pigmentation and greying: Role of mTORC1 activity T Suzuki, J Chéret, FD Scala, J Gherardini, J O’Sullivan, G Epstein-Kuka, ... Journal of Investigative Dermatology 142 (12), S270, 2022 | 1* | 2022 |
Aurelio TelemanGerman Cancer Research Center在 dkfz.de 的电子邮件经过验证
