| Stable, soluble T‐cell receptor molecules for crystallization and therapeutics JM Boulter, M Glick, PT Todorov, E Baston, M Sami, P Rizkallah, ... Protein engineering 16 (9), 707-711, 2003 | 1022 | 2003 |
| Analysis of pharmacology data and the prediction of adverse drug reactions and off‐target effects from chemical structure A Bender, J Scheiber, M Glick, JW Davies, K Azzaoui, J Hamon, L Urban, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (6), 861-873, 2007 | 387 | 2007 |
| From in silico target prediction to multi-target drug design: Current databases, methods and applications A Koutsoukas, B Simms, J Kirchmair, PJ Bond, AV Whitmore, S Zimmer, ... Journal of proteomics 74 (12), 2554-2574, 2011 | 350 | 2011 |
| How similar are similarity searching methods? A principal component analysis of molecular descriptor space A Bender, JL Jenkins, J Scheiber, SCK Sukuru, M Glick, JW Davies Journal of chemical information and modeling 49 (1), 108-119, 2009 | 337 | 2009 |
| Prediction of biological targets for compounds using multiple-category Bayesian models trained on chemogenomics databases Nidhi, M Glick, JW Davies, JL Jenkins Journal of chemical information and modeling 46 (3), 1124-1133, 2006 | 334 | 2006 |
| Bridging chemical and biological space:“target fishing” using 2D and 3D molecular descriptors JH Nettles, JL Jenkins, A Bender, Z Deng, JW Davies, M Glick Journal of medicinal chemistry 49 (23), 6802-6810, 2006 | 226 | 2006 |
| Interaction between the CD8 coreceptor and major histocompatibility complex class I stabilizes T cell receptor-antigen complexes at the cell surface L Wooldridge, HA van den Berg, M Glick, E Gostick, B Laugel, ... Journal of Biological Chemistry 280 (30), 27491-27501, 2005 | 209 | 2005 |
| Mapping adverse drug reactions in chemical space J Scheiber, JL Jenkins, SCK Sukuru, A Bender, D Mikhailov, M Milik, ... Journal of medicinal chemistry 52 (9), 3103-3107, 2009 | 195 | 2009 |
| Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ... Journal of chemical information and modeling 49 (2), 308-317, 2009 | 192 | 2009 |
| Rethinking molecular similarity: comparing compounds on the basis of biological activity PM Petrone, B Simms, F Nigsch, E Lounkine, P Kutchukian, A Cornett, ... ACS chemical biology 7 (8), 1399-1409, 2012 | 165 | 2012 |
| A 3D similarity method for scaffold hopping from known drugs or natural ligands to new chemotypes JL Jenkins, M Glick, JW Davies Journal of medicinal chemistry 47 (25), 6144-6159, 2004 | 161 | 2004 |
| Streamlining lead discovery by aligning in silico and high-throughput screening JW Davies, M Glick, JL Jenkins Current opinion in chemical biology 10 (4), 343-351, 2006 | 144 | 2006 |
| Identification of TNO155, an allosteric SHP2 inhibitor for the treatment of cancer MJ LaMarche, M Acker, A Argintaru, D Bauer, J Boisclair, H Chan, ... Journal of medicinal chemistry 63 (22), 13578-13594, 2020 | 140 | 2020 |
| Dark chemical matter as a promising starting point for drug lead discovery AM Wassermann, E Lounkine, D Hoepfner, G Le Goff, FJ King, C Studer, ... Nature chemical biology 11 (12), 958-966, 2015 | 139 | 2015 |
| Enrichment of high-throughput screening data with increasing levels of noise using support vector machines, recursive partitioning, and laplacian-modified naive bayesian … M Glick, JL Jenkins, JH Nettles, H Hitchings, JW Davies Journal of chemical information and modeling 46 (1), 193-200, 2006 | 138 | 2006 |
| “Bayes affinity fingerprints” improve retrieval rates in virtual screening and define orthogonal bioactivity space: when are multitarget drugs a feasible concept? A Bender, JL Jenkins, M Glick, Z Deng, JH Nettles, JW Davies Journal of chemical information and modeling 46 (6), 2445-2456, 2006 | 132 | 2006 |
| Finding more needles in the haystack: A simple and efficient method for improving high-throughput docking results AE Klon, M Glick, M Thoma, P Acklin, JW Davies Journal of medicinal chemistry 47 (11), 2743-2749, 2004 | 128 | 2004 |
| Dual allosteric inhibition of SHP2 phosphatase M Fodor, E Price, P Wang, H Lu, A Argintaru, Z Chen, M Glick, HX Hao, ... ACS chemical biology 13 (3), 647-656, 2018 | 116 | 2018 |
| Soluble T cell receptor BK Jakobsen, M Glick US Patent 7,329,731, 2008 | 107 | 2008 |
| The CD8 T cell coreceptor exhibits disproportionate biological activity at extremely low binding affinities SL Hutchinson, L Wooldridge, S Tafuro, B Laugel, M Glick, JM Boulter, ... Journal of Biological Chemistry 278 (27), 24285-24293, 2003 | 107 | 2003 |
