| Role of intermolecular forces in defining material properties of protein nanofibrils TP Knowles, AW Fitzpatrick, S Meehan, HR Mott, M Vendruscolo, ... science 318 (5858), 1900-1903, 2007 | 865 | 2007 |
| Metastability of native proteins and the phenomenon of amyloid formation AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ... Journal of the American Chemical Society 133 (36), 14160-14163, 2011 | 507 | 2011 |
| The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures JJ Yerbury, S Poon, S Meehan, B Thompson, JR Kumita, CM Dobson, ... The FASEB Journal 21 (10), 2312-2322, 2007 | 368 | 2007 |
| The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide P Narayan, A Orte, RW Clarke, B Bolognesi, S Hook, KA Ganzinger, ... Nature structural & molecular biology 19 (1), 79-83, 2012 | 307 | 2012 |
| Iron promotes the toxicity of amyloid β peptide by impeding its ordered aggregation B Liu, A Moloney, S Meehan, K Morris, SE Thomas, LC Serpell, R Hider, ... Journal of Biological Chemistry 286 (6), 4248-4256, 2011 | 267 | 2011 |
| Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass TPJ Knowles, W Shu, GL Devlin, S Meehan, S Auer, CM Dobson, ... Proceedings of the National Academy of Sciences 104 (24), 10016-10021, 2007 | 241 | 2007 |
| Amyloid Fibril Formation by Bovine Milk κ-Casein and Its Inhibition by the Molecular Chaperones αS- and β-Casein DC Thorn, S Meehan, M Sunde, A Rekas, SL Gras, CE MacPhee, ... Biochemistry 44 (51), 17027-17036, 2005 | 234 | 2005 |
| Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation S Meehan, Y Berry, B Luisi, CM Dobson, JA Carver, CE MacPhee Journal of Biological Chemistry 279 (5), 3413-3419, 2004 | 218 | 2004 |
| Small heat-shock proteins: important players in regulating cellular proteostasis TM Treweek, S Meehan, H Ecroyd, JA Carver Cellular and molecular life sciences 72, 429-451, 2015 | 215 | 2015 |
| Structure and properties of a complex of α-synuclein and a single-domain camelid antibody EJ De Genst, T Guilliams, J Wellens, EM O'day, CA Waudby, S Meehan, ... Journal of molecular biology 402 (2), 326-343, 2010 | 209 | 2010 |
| Mimicking phosphorylation of αB-crystallin affects its chaperone activity H Ecroyd, S Meehan, J Horwitz, JA Aquilina, JLP Benesch, CV Robinson, ... Biochemical Journal 401 (1), 129-141, 2007 | 200 | 2007 |
| Binding of the molecular chaperone αB-crystallin to Aβ amyloid fibrils inhibits fibril elongation SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ... Biophysical journal 101 (7), 1681-1689, 2011 | 187 | 2011 |
| The interaction of αB-crystallin with mature α-synuclein amyloid fibrils inhibits their elongation CA Waudby, TPJ Knowles, GL Devlin, JN Skepper, H Ecroyd, JA Carver, ... Biophysical journal 98 (5), 843-851, 2010 | 173 | 2010 |
| Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers B Mannini, R Cascella, M Zampagni, M van Waarde-Verhagen, S Meehan, ... Proceedings of the National Academy of Sciences 109 (31), 12479-12484, 2012 | 168 | 2012 |
| Hsp90 inhibits α-synuclein aggregation by interacting with soluble oligomers S Daturpalli, CA Waudby, S Meehan, SE Jackson Journal of molecular biology 425 (22), 4614-4628, 2013 | 129 | 2013 |
| Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human αA-, αB-and R120G αB-crystallins S Meehan, TPJ Knowles, AJ Baldwin, JF Smith, AM Squires, P Clements, ... Journal of molecular biology 372 (2), 470-484, 2007 | 113 | 2007 |
| α2-Macroglobulin and haptoglobin suppress amyloid formation by interacting with prefibrillar protein species JJ Yerbury, JR Kumita, S Meehan, CM Dobson, MR Wilson Journal of Biological Chemistry 284 (7), 4246-4254, 2009 | 108 | 2009 |
| Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells P Narayan, KA Ganzinger, J McColl, L Weimann, S Meehan, S Qamar, ... Journal of the American Chemical Society 135 (4), 1491-1498, 2013 | 94 | 2013 |
| Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones P Narayan, S Meehan, JA Carver, MR Wilson, CM Dobson, D Klenerman Biochemistry 51 (46), 9270-9276, 2012 | 94 | 2012 |
| The Aggregation and Neurotoxicity of TDP-43 and Its ALS-Associated 25 kDa Fragment Are Differentially Affected by Molecular Chaperones in Drosophila JM Gregory, TP Barros, S Meehan, CM Dobson, LM Luheshi PloS one 7 (2), e31899, 2012 | 79 | 2012 |
