Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons O Varea, MD Martin-de-Saavedra, KJ Kopeikina, B Schürmann, ... Proceedings of the National Academy of Sciences 112 (19), 6176-6181, 2015 | 140 | 2015 |
Nrf2 participates in depressive disorders through an anti-inflammatory mechanism MD Martín-de-Saavedra, J Budni, MP Cunha, V Gómez-Rangel, S Lorrio, ... Psychoneuroendocrinology 38 (10), 2010-2022, 2013 | 139 | 2013 |
Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway T Dal-Cim, S Molz, J Egea, E Parada, A Romero, J Budni, ... Neurochemistry International 61 (3), 397-404, 2012 | 129 | 2012 |
Neuroprotective effect of guanosine against glutamate‐induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol‐3 kinase/Akt/glycogen synthase kinase … S Molz, T Dal‐Cim, J Budni, MD Martín‐de‐Saavedra, J Egea, A Romero, ... Journal of neuroscience research 89 (9), 1400-1408, 2011 | 86 | 2011 |
Reversal of dendritic phenotypes in 16p11. 2 microduplication mouse model neurons by pharmacological targeting of a network hub KD Blizinsky, B Diaz-Castro, MP Forrest, B Schürmann, AP Bach, ... Proceedings of the National Academy of Sciences 113 (30), 8520-8525, 2016 | 77 | 2016 |
Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation J Egea, MD Martín-de-Saavedra, E Parada, A Romero, L Del Barrio, ... Neuropharmacology 62 (2), 1082-1090, 2012 | 77 | 2012 |
Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice J Budni, KR Lobato, RW Binfaré, AE Freitas, AP Costa, ... Journal of Psychopharmacology 26 (5), 714-723, 2012 | 66 | 2012 |
Cholinergic and neuroprotective drugs for the treatment of Alzheimer and neuronal vascular diseases. II. Synthesis, biological assessment, and molecular modelling of new … A Samadi, C Valderas, C De Los Ríos, A Bastida, M Chioua, ... Bioorganic & medicinal chemistry 19 (1), 122-133, 2011 | 66 | 2011 |
Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation L Del Barrio, MD Martín-de-Saavedra, A Romero, E Parada, J Egea, ... Toxicological Sciences 123 (1), 193-205, 2011 | 62 | 2011 |
A novel role for the late-onset Alzheimer’s disease (LOAD)-associated protein Bin1 in regulating postsynaptic trafficking and glutamatergic signaling B Schürmann, DP Bermingham, KJ Kopeikina, K Myczek, S Yoon, ... Molecular psychiatry 25 (9), 2000-2016, 2020 | 58 | 2020 |
N-acylaminophenothiazines: Neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer’s disease GC González-Muñoz, MP Arce, B López, C Pérez, A Romero, L del Barrio, ... European journal of medicinal chemistry 46 (6), 2224-2235, 2011 | 57 | 2011 |
CNTNAP2 stabilizes interneuron dendritic arbors through CASK R Gao, NH Piguel, AE Melendez-Zaidi, MD Martin-de-Saavedra, S Yoon, ... Molecular psychiatry 23 (9), 1832-1850, 2018 | 53 | 2018 |
The modulation of NMDA receptors and l-arginine/nitric oxide pathway is implicated in the anti-immobility effect of creatine in the tail suspension test MP Cunha, FL Pazini, FK Ludka, JM Rosa, Á Oliveira, J Budni, ... Amino acids 47, 795-811, 2015 | 47 | 2015 |
Both Creatine and Its Product Phosphocreatine Reduce Oxidative Stress and Afford Neuroprotection in an In Vitro Parkinson’s Model MP Cunha, MD Martin-de-Saavedra, A Romero, J Egea, FK Ludka, ... ASN neuro 6 (6), 1759091414554945, 2014 | 47 | 2014 |
Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: involvement of intracellular signaling pathways MP Cunha, MD Martín-de-Saavedra, A Romero, E Parada, J Egea, ... Neuroscience 238, 185-194, 2013 | 43 | 2013 |
Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid J Budni, A Romero, S Molz, MD Martín-de-Saavedra, J Egea, L Del Barrio, ... Neuroscience 190, 346-353, 2011 | 38 | 2011 |
Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS MD Martín-de-Saavedra, L del Barrio, N Canas, J Egea, S Lorrio, ... Neurochemistry international 58 (6), 676-683, 2011 | 36 | 2011 |
Rapid 3D enhanced resolution microscopy reveals diversity in dendritic spinule dynamics, regulation, and function CR Zaccard, L Shapiro, MD Martin-de-Saavedra, C Pratt, K Myczek, ... Neuron 107 (3), 522-537. e6, 2020 | 33 | 2020 |
Inhibition of calpain-regulated p35/cdk5 plays a central role in sildenafil-induced protection against chemical hypoxia produced by malonate L Barros-Miñones, D Martín-de-Saavedra, S Perez-Alvarez, L Orejana, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (6), 705-717, 2013 | 29 | 2013 |
Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2 MD Martín-de-Saavedra, M Dos Santos, L Culotta, O Varea, BP Spielman, ... Neuron 110 (4), 627-643. e9, 2022 | 20 | 2022 |