关注
William M Dawson
William M Dawson
Senior Scientist, Oxford Nanopore Technologies
在 nanoporetech.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Installing hydrolytic activity into a completely de novo protein framework
AJ Burton, AR Thomson, WM Dawson, RL Brady, DN Woolfson
Nature chemistry 8 (9), 837-844, 2016
1972016
Unraveling the role of protein dynamics in dihydrofolate reductase catalysis
LYP Luk, J Javier Ruiz-Pernia, WM Dawson, M Roca, EJ Loveridge, ...
Proceedings of the National Academy of Sciences 110 (41), 16344-16349, 2013
1492013
Constructing ion channels from water-soluble α-helical barrels
AJ Scott, A Niitsu, HT Kratochvil, EJM Lang, JT Sengel, WM Dawson, ...
Nature chemistry 13 (7), 643-650, 2021
742021
De Novo-Designed α-Helical Barrels as Receptors for Small Molecules
F Thomas, WM Dawson, EJM Lang, AJ Burton, GJ Bartlett, GG Rhys, ...
ACS Synthetic Biology 7 (7), 1808-1816, 2018
742018
Towards functional de novo designed proteins
WM Dawson, GG Rhys, DN Woolfson
Current Opinion in Chemical Biology 52, 102-111, 2019
702019
Decorating self-assembled peptide cages with proteins
JF Ross, A Bridges, JM Fletcher, D Shoemark, D Alibhai, HEV Bray, ...
ACS nano 11 (8), 7901-7914, 2017
642017
The role of large-scale motions in catalysis by dihydrofolate reductase
EJ Loveridge, LH Tey, EM Behiry, WM Dawson, RM Evans, ...
Journal of the American Chemical Society 133 (50), 20561-20570, 2011
502011
Coiled coils 9-to-5: rational de novo design of α-helical barrels with tunable oligomeric states
WM Dawson, FJO Martin, GG Rhys, KL Shelley, RL Brady, DN Woolfson
Chemical Science 12 (20), 6923-6928, 2021
472021
Protein Isotope Effects in Dihydrofolate Reductase From Geobacillus stearothermophilus Show Entropic–Enthalpic Compensatory Effects on the Rate Constant
LYP Luk, JJ Ruiz-Pernía, WM Dawson, EJ Loveridge, I Tuñón, V Moliner, ...
Journal of the American Chemical Society 136 (49), 17317-17323, 2014
392014
A Versatile Disulfide-Driven Recycling System for NADP+ with High Cofactor Turnover Number
A Angelastro, WM Dawson, LYP Luk, RK Allemann
ACS Catalysis 7 (2), 1025-1029, 2017
332017
Structural resolution of switchable states of a de novo peptide assembly
WM Dawson, EJM Lang, GG Rhys, KL Shelley, C Williams, RL Brady, ...
Nature Communications 12 (1), 1530, 2021
272021
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy
T Kataura, EG Otten, Y Rabanal‐Ruiz, E Adriaenssens, F Urselli, F Scialo, ...
The EMBO Journal 42 (5), e111372, 2023
252023
De novo designed peptides for cellular delivery and subcellular localisation
GG Rhys, JA Cross, WM Dawson, HF Thompson, S Shanmugaratnam, ...
Nature Chemical Biology 18 (9), 999-1004, 2022
212022
Differential sensing with arrays of de novo designed peptide assemblies
WM Dawson, KL Shelley, JM Fletcher, DA Scott, L Lombardi, GG Rhys, ...
Nature Communications 14 (1), 383, 2023
112023
How coiled-coil assemblies accommodate multiple aromatic residues
GG Rhys, WM Dawson, JL Beesley, FJO Martin, RL Brady, AR Thomson, ...
Biomacromolecules 22 (5), 2010-2019, 2021
92021
Chemoenzymatic assembly of isotopically labeled folates
A Angelastro, WM Dawson, LYP Luk, EJ Loveridge, RK Allemann
Journal of the American Chemical Society 139 (37), 13047-13054, 2017
42017
Reduced Susceptibility of Moritella profunda Dihydrofolate Reductase to Trimethoprim is Not Due to Glutamate 28
EJ Loveridge, WM Dawson, RM Evans, A Sobolewska, RK Allemann
The Protein Journal 30, 546-548, 2011
32011
CC+: A searchable database of validated coiled coils in PDB structures and AlphaFold2 models
P Kumar, R Petrenas, WM Dawson, H Schweke, ED Levy, DN Woolfson
Protein science 32 (11), e4789, 2023
22023
Aliphatic 1H, 13C and 15N chemical shift assignments of dihydrofolate reductase from the psychropiezophile Moritella profunda in complex with NADP+ and folate
EJ Loveridge, SM Matthews, C Williams, SBM Whittaker, UL Günther, ...
Biomolecular NMR assignments 7, 61-64, 2013
22013
Rationally seeded computational protein design of ɑ-helical barrels
KI Albanese, R Petrenas, F Pirro, EA Naudin, U Borucu, WM Dawson, ...
Nature Chemical Biology, 1-9, 2024
2024
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