A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons X Zhao, Z Tang, H Zhang, FE Atianjoh, JY Zhao, L Liang, W Wang, ... Nature neuroscience 16 (8), 1024-1031, 2013 | 375 | 2013 |
Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction F Huang, H Zhang, M Wu, H Yang, M Kudo, CJ Peters, PG Woodruff, ... Proceedings of the National Academy of Sciences 109 (40), 16354-16359, 2012 | 371 | 2012 |
Impaired neuropathic pain and preserved acute pain in rats overexpressing voltage-gated potassium channel subunit Kv1. 2 in primary afferent neurons L Fan, X Guan, W Wang, JY Zhao, H Zhang, V Tiwari, PN Hoffman, M Li, ... Molecular pain 10, 1744-8069-10-8, 2014 | 102 | 2014 |
Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels H Yu, Z Lin, ME Mattmann, B Zou, C Terrenoire, H Zhang, M Wu, ... Proceedings of the National Academy of Sciences 110 (21), 8732-8737, 2013 | 94 | 2013 |
Optical electrophysiology for probing function and pharmacology of voltage-gated ion channels H Zhang, E Reichert, AE Cohen Elife 5, e15202, 2016 | 73 | 2016 |
Optically controlled oscillators in an engineered bioelectric tissue HM McNamara, H Zhang, CA Werley, AE Cohen Physical Review X 6 (3), 031001, 2016 | 71 | 2016 |
Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel H Zhang, B Zou, H Yu, A Moretti, X Wang, W Yan, JJ Babcock, M Bellin, ... Proceedings of the National Academy of Sciences 109 (29), 11866-11871, 2012 | 65 | 2012 |
All-optical electrophysiology for high-throughput functional characterization of a human iPSC-derived motor neuron model of ALS E Kiskinis, JM Kralj, P Zou, EN Weinstein, H Zhang, K Tsioras, O Wiskow, ... Stem cell reports 10 (6), 1991-2004, 2018 | 63 | 2018 |
Optogenetic approaches to drug discovery in neuroscience and beyond H Zhang, AE Cohen Trends in biotechnology 35 (7), 625-639, 2017 | 49 | 2017 |
Identification of novel small molecule modulators of K2P18. 1 two-pore potassium channel JK Bruner, B Zou, H Zhang, Y Zhang, K Schmidt, M Li European journal of pharmacology 740, 603-610, 2014 | 40 | 2014 |
Reporting sodium channel activity using calcium flux: pharmacological promiscuity of cardiac Nav1. 5 H Zhang, B Zou, F Du, K Xu, M Li Molecular pharmacology 87 (2), 207-217, 2015 | 16 | 2015 |
Correlation of Optical and Automated Patch Clamp Electrophysiology for Identification of NaV1.7 Inhibitors H Zhang, BD Moyer, V Yu, JG McGivern, M Jarosh, CA Werley, VC Hecht, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (5), 434-446, 2020 | 6 | 2020 |
Highly parallelized, multicolor optogenetic recordings of cellular activity for therapeutic discovery applications in ion channels and disease-associated excitable cells GB Borja, H Zhang, BN Harwood, J Jacques, J Grooms, RO Chantre, ... Frontiers in Molecular Neuroscience 15, 896320, 2022 | 4 | 2022 |
A phenotypic screening platform for chronic pain therapeutics using all-optical electrophysiology PW Liu, H Zhang, CA Werley, M Pichler, SJ Ryan, CL Lewarch, J Jacques, ... Pain 165 (4), 922-940, 2024 | 3 | 2024 |
Discovery of novel compounds and target mechanisms using a high throughput, multiparametric phenotypic screen in a human neuronal model of Tuberous Sclerosis LA Williams, SJ Ryan, V Joshi, C Lewarch, A Elder, O McManus, ... bioRxiv, 2024.02. 22.581652, 2024 | 1 | 2024 |