The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein PJ Lu, G Wulf, XZ Zhou, P Davies, KP Lu Nature 399 (6738), 784-788, 1999 | 948 | 1999 |
Function of WW domains as phosphoserine-or phosphothreonine-binding modules PJ Lu, XZ Zhou, M Shen, KP Lu Science 283 (5406), 1325-1328, 1999 | 891 | 1999 |
Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins XZ Zhou, O Kops, A Werner, PJ Lu, M Shen, G Stoller, G Küllertz, M Stark, ... Molecular cell 6 (4), 873-883, 2000 | 711 | 2000 |
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production L Pastorino, A Sun, PJ Lu, XZ Zhou, M Balastik, G Finn, G Wulf, J Lim, ... Nature 440 (7083), 528-534, 2006 | 592 | 2006 |
Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes YC Liou, A Ryo, HK Huang, PJ Lu, R Bronson, F Fujimori, T Uchida, ... Proceedings of the National Academy of Sciences 99 (3), 1335-1340, 2002 | 442 | 2002 |
Critical role of WW domain phosphorylation in regulating phosphoserine binding activity and Pin1 function PJ Lu, XZ Zhou, YC Liou, JP Noel, KP Lu Journal of Biological Chemistry 277 (4), 2381-2384, 2002 | 318 | 2002 |
MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway IS Hsieh, KC Chang, YT Tsai, JY Ke, PJ Lu, KH Lee, SD Yeh, TM Hong, ... Carcinogenesis 34 (3), 530-538, 2013 | 244 | 2013 |
MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation KH Lee, YL Chen, SD Yeh, M Hsiao, JT Lin, YG Goan, PJ Lu Oncogene 28 (38), 3360-3370, 2009 | 240 | 2009 |
Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling YP Liu, CJ Yang, MS Huang, CT Yeh, ATH Wu, YC Lee, TC Lai, CH Lee, ... Cancer research 73 (1), 406-416, 2013 | 238 | 2013 |
MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer KH Lee, YG Goan, M Hsiao, CH Lee, SH Jian, JT Lin, YL Chen, PJ Lu Experimental cell research 315 (15), 2529-2538, 2009 | 234 | 2009 |
Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer CT Yeh, ATH Wu, PMH Chang, KY Chen, CN Yang, SC Yang, CC Ho, ... American journal of respiratory and critical care medicine 186 (11), 1180-1188, 2012 | 215 | 2012 |
Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism XZ Zhou, PJ Lu, G Wulf, KP Lu Cellular and Molecular Life Sciences CMLS 56, 788-806, 1999 | 188 | 1999 |
miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer HY Li, JL Liang, YL Kuo, HH Lee, MJ Calkins, HT Chang, FC Lin, ... Breast Cancer Research 19, 1-14, 2017 | 172 | 2017 |
Lipid products of phosphoinositide 3-kinase bind human profilin with high affinity PJ Lu, WR Shieh, SG Rhee, HL Yin, CS Chen Biochemistry 35 (44), 14027-14034, 1996 | 172 | 1996 |
TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer MC Shih, JY Chen, YC Wu, YH Jan, BM Yang, PJ Lu, HC Cheng, ... Oncogene 31 (19), 2389-2400, 2012 | 170 | 2012 |
Glycogen synthase kinase‐3 negatively regulates anti‐inflammatory interleukin‐10 for lipopolysaccharide‐induced iNOS/NO biosynthesis and RANTES production in microglial cells WC Huang, YS Lin, CY Wang, CC Tsai, HC Tseng, CL Chen, PJ Lu, ... Immunology 128 (1pt2), e275-e286, 2009 | 159 | 2009 |
MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1 KH Lee, FC Lin, TI Hsu, JT Lin, JH Guo, CH Tsai, YC Lee, YC Lee, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1843 (9), 2055-2066, 2014 | 121 | 2014 |
Gelsolin binding to phosphatidylinositol 4, 5-bisphosphate is modulated by calcium and pH KM Lin, E Wenegieme, PJ Lu, CS Chen, HL Yin Journal of Biological Chemistry 272 (33), 20443-20450, 1997 | 120 | 1997 |
MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo TI Hsu, CH Hsu, KH Lee, JT Lin, CS Chen, KC Chang, CYJ Su, M Hsiao, ... Oncogenesis 3 (4), e99-e99, 2014 | 119 | 2014 |
Synthesis and antiproliferative evaluation of certain indeno [1, 2-c] quinoline derivatives CH Tseng, YL Chen, PJ Lu, CN Yang, CC Tzeng Bioorganic & medicinal chemistry 16 (6), 3153-3162, 2008 | 116 | 2008 |