| Drug repositioning: a brief overview JP Jourdan, R Bureau, C Rochais, P Dallemagne Journal of Pharmacy and Pharmacology 72 (9), 1145-1151, 2020 | 291 | 2020 |
| New aromatase inhibitors. Synthesis and biological activity of aryl-substituted pyrrolizine and indolizine derivatives P Sonnet, P Dallemagne, J Guillon, C Enguehard, S Stiebing, J Tanguy, ... Bioorganic & medicinal chemistry 8 (5), 945-955, 2000 | 156 | 2000 |
| Lewis acid-promoted selective rearrangement of trisubstituted epoxides to aldehydes or ketones K Maruoka, N Murase, R Bureau, T Ooi, H Yamamoto Tetrahedron 50 (12), 3663-3672, 1994 | 99 | 1994 |
| Toward safer thrombolytic agents in stroke: molecular requirements for NMDA receptor-mediated neurotoxicity JP Lopez-Atalaya, BD Roussel, D Levrat, J Parcq, O Nicole, Y Hommet, ... Journal of Cerebral Blood Flow & Metabolism 28 (6), 1212-1221, 2008 | 95 | 2008 |
| Acute toxicity of 8 antidepressants: what are their modes of action? L Minguez, E Farcy, C Ballandonne, A Lepailleur, A Serpentini, JM Lebel, ... Chemosphere 108, 314-319, 2014 | 90 | 2014 |
| Hot-spots of Mcl-1 protein: miniperspective C Denis, J Sopková-de Oliveira Santos, R Bureau, AS Voisin-Chiret Journal of medicinal chemistry 63 (3), 928-943, 2019 | 70 | 2019 |
| Synthesis and biological evaluation of five-membered heterocycles fused to cyclopenta [c] thiophene as new antitumor agents P Dallemagne, LP Khanh, A Alsaı̈di, I Varlet, V Collot, M Paillet, ... Bioorganic & medicinal chemistry 11 (7), 1161-1167, 2003 | 70 | 2003 |
| New Benzo[h][1,6]naphthyridine and Azepino[3,2-c]quinoline Derivatives as Selective Antagonists of 5-HT4 Receptors: Binding Profile and Pharmacological … A Hinschberger, S Butt, V Lelong, M Boulouard, A Dumuis, F Dauphin, ... Journal of medicinal chemistry 46 (1), 138-147, 2003 | 61 | 2003 |
| Synthesis of new dipyrrolo-and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1–5, GSK-3) inhibitors C Rochais, NV Duc, E Lescot, J Sopkova-de Oliveira Santos, R Bureau, ... European journal of medicinal chemistry 44 (2), 708-716, 2009 | 58 | 2009 |
| First Evidence That Oligopyridines, α-Helix Foldamers, Inhibit Mcl-1 and Sensitize Ovarian Carcinoma Cells to Bcl-xL-Targeting Strategies C Gloaguen, AS Voisin-Chiret, J Sopkova-de Oliveira Santos, J Fogha, ... Journal of medicinal chemistry 58 (4), 1644-1668, 2015 | 54 | 2015 |
| The maximum common substructure as a molecular depiction in a supervised classification context: experiments in quantitative structure/biodegradability relationships B Cuissart, F Touffet, B Crémilleux, R Bureau, S Rault Journal of chemical information and computer sciences 42 (5), 1043-1052, 2002 | 53 | 2002 |
| Acute toxicities of pharmaceuticals toward green algae. mode of action, biopharmaceutical drug disposition classification system and quantile regression models J Villain, L Minguez, MP Halm-Lemeille, G Durrieu, R Bureau Ecotoxicology and Environmental Safety 124, 337-343, 2016 | 51 | 2016 |
| Clustering files of chemical structures using the Székely–Rizzo generalization of Ward's method T Varin, R Bureau, C Mueller, P Willett Journal of Molecular Graphics and Modelling 28 (2), 187-195, 2009 | 50 | 2009 |
| Study of substrate specificity of human aromatase by site directed mutagenesis P Auvray, C Nativelle, R Bureau, P Dallemagne, GE Séralini, P Sourdaine European journal of biochemistry 269 (5), 1393-1405, 2002 | 47 | 2002 |
| Prediction of the fish acute toxicity from heterogeneous data coming from notification files JC Faucon, R Bureau, J Faisant, F Briens, S Rault Chemosphere 38 (14), 3261-3276, 1999 | 47 | 1999 |
| The Arg–Phe‐amide peptide 26RFa/glutamine RF‐amide peptide and its receptor: IUPHAR Review 24 J Leprince, D Bagnol, R Bureau, S Fukusumi, R Granata, S Hinuma, ... British journal of pharmacology 174 (20), 3573-3607, 2017 | 45 | 2017 |
| A three‐site mechanism for agonist/antagonist selective binding to vasopressin receptors N Saleh, G Saladino, FL Gervasio, E Haensele, L Banting, DC Whitley, ... Angewandte Chemie 128 (28), 8140-8144, 2016 | 45 | 2016 |
| Definition of a Pharmacophore for Partial Agonists of Serotonin 5-HT3 Receptors C Daveu, R Bureau, I Baglin, H Prunier, JC Lancelot, S Rault Journal of chemical information and computer sciences 39 (2), 362-369, 1999 | 45 | 1999 |
| Phenylpyrroles, a new chemolibrary virtual screening class of 5-HT7 receptor ligands M Paillet-Loilier, F Fabis, A Lepailleur, R Bureau, S Butt-Gueulle, ... Bioorganic & medicinal chemistry letters 15 (16), 3753-3757, 2005 | 44 | 2005 |
| Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata) L Minguez, MP Halm-Lemeille, K Costil, R Bureau, JM Lebel, A Serpentini Aquatic Toxicology 153, 3-11, 2014 | 43 | 2014 |
