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Effect of hydrocortisone on mortality and organ support in patients with severe COVID-19: the REMAP-CAP COVID-19 corticosteroid domain randomized clinical trial DC Angus, L Derde, F Al-Beidh, D Annane, Y Arabi, A Beane, ... Jama 324 (13), 1317-1329, 2020 | 835 | 2020 |
Interleukin-6 receptor antagonists in critically ill patients with Covid-19 Remap-Cap Investigators New England Journal of Medicine 384 (16), 1491-1502, 2021 | 613 | 2021 |
Association between administration of IL-6 antagonists and mortality among patients hospitalized for COVID-19: a meta-analysis P Domingo, I Mur, GM Mateo, M del Mar Gutierrez, V Pomar, N de Benito, ... Jama 326 (6), 499-518, 2021 | 476 | 2021 |
Safety and efficacy of intravenous iron therapy in reducing requirement for allogeneic blood transfusion: systematic review and meta-analysis of randomised clinical trials E Litton, J Xiao, KM Ho Bmj 347, 2013 | 440 | 2013 |
Conservative oxygen therapy during mechanical ventilation in the ICU. D Mackle, R Bellomo, M Bailey, R Beasley, A Deane, G Eastwood, ... The New England journal of medicine 382 (11), 989-998, 2019 | 329 | 2019 |
Intubation practices and adverse peri-intubation events in critically ill patients from 29 countries V Russotto, SN Myatra, JG Laffey, E Tassistro, L Antolini, P Bauer, ... Jama 325 (12), 1164-1172, 2021 | 324 | 2021 |
The REMAP-CAP (randomized embedded multifactorial adaptive platform for community-acquired pneumonia) study. Rationale and design DC Angus, S Berry, RJ Lewis, F Al-Beidh, Y Arabi, W van Bentum-Puijk, ... Annals of the American Thoracic Society 17 (7), 879-891, 2020 | 314 | 2020 |
Use of chlorhexidine-impregnated dressing to prevent vascular and epidural catheter colonization and infection: a meta-analysis KM Ho, E Litton Journal of Antimicrobial Chemotherapy 58 (2), 281-287, 2006 | 277 | 2006 |
The PiCCO monitor: a review E Litton*, M Morgan Anaesthesia and intensive care 40 (3), 393-408, 2012 | 234 | 2012 |
Effect of convalescent plasma on organ support–free days in critically ill patients with COVID-19: a randomized clinical trial H Abdelhady, M Abdelrazik, Z Abdi, D Abdo, A Abdulle, L Abel, ... Jama 326 (17), 1690-1702, 2021 | 193 | 2021 |
The efficacy of earplugs as a sleep hygiene strategy for reducing delirium in the ICU: a systematic review and meta-analysis E Litton, V Carnegie, R Elliott, SAR Webb Critical care medicine 44 (5), 992-999, 2016 | 189 | 2016 |
Effect of stress ulcer prophylaxis with proton pump inhibitors vs histamine-2 receptor blockers on in-hospital mortality among ICU patients receiving invasive mechanical … PJ Young, SM Bagshaw, AB Forbes, AD Nichol, SE Wright, M Bailey, ... Jama 323 (7), 616-626, 2020 | 137 | 2020 |
Surge capacity of intensive care units in case of acute increase in demand caused by COVID‐19 in Australia E Litton, T Bucci, S Chavan, YY Ho, A Holley, G Howard, S Huckson, ... Medical Journal of Australia 212 (10), 463-467, 2020 | 132 | 2020 |
Restricted fluid resuscitation in suspected sepsis associated hypotension (REFRESH): a pilot randomised controlled trial SPJ Macdonald, G Keijzers, DMD Taylor, F Kinnear, G Arendts, ... Intensive care medicine 44, 2070-2078, 2018 | 115 | 2018 |
Intravenous iron or placebo for anaemia in intensive care: the IRONMAN multicentre randomized blinded trial: a randomized trial of IV iron in critical illness Ironman Investigators, E Litton, S Baker, WN Erber, S Farmer, J Ferrier, ... Intensive care medicine 42, 1715-1722, 2016 | 114 | 2016 |
Choosing primary endpoints for clinical trials of health care interventions C McLeod, R Norman, E Litton, BR Saville, S Webb, TL Snelling Contemporary clinical trials communications 16, 100486, 2019 | 107 | 2019 |
Cardiac prehabilitation M McCann, N Stamp, A Ngui, E Litton Journal of cardiothoracic and vascular anesthesia 33 (8), 2255-2265, 2019 | 99 | 2019 |
Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial YM Arabi, AC Gordon, LPG Derde, AD Nichol, S Murthy, FA Beidh, ... Intensive care medicine 47, 867-886, 2021 | 90 | 2021 |
Long-term (180-day) outcomes in critically ill patients with COVID-19 in the REMAP-CAP randomized clinical trial S Florescu, D Stanciu, M Zaharia, A Kosa, D Codreanu, A Kidwai, ... Jama 329 (1), 39-51, 2023 | 88 | 2023 |