Platelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapies XR Xu, N Carrim, MAD Neves, T McKeown, TW Stratton, RMP Coelho, ... Thrombosis journal 14, 37-46, 2016 | 197 | 2016 |
Anfibatide, a novel GPIb complex antagonist, inhibits platelet adhesion and thrombus formation in vitro and in vivo in murine models of thrombosis X Lei, A Reheman, Y Hou, H Zhou, Y Wang, AH Marshall, C Liang, X Dai, ... Thrombosis and haemostasis 112 (02), 279-289, 2014 | 147 | 2014 |
Glucagon-like peptide 1 receptor activation attenuates platelet aggregation and thrombosis A Cameron-Vendrig, A Reheman, MA Siraj, XR Xu, Y Wang, X Lei, ... Diabetes 65 (6), 1714-1723, 2016 | 114 | 2016 |
Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis XR Xu, Y Wang, R Adili, L Ju, CM Spring, JW Jin, H Yang, MAD Neves, ... Nature communications 9 (1), 3608, 2018 | 95 | 2018 |
The role of endothelial cell adhesion molecules P‐selectin, E‐selectin and intercellular adhesion molecule‐1 in leucocyte recruitment induced by exogenous methylglyoxal Y Su, X Lei, L Wu, L Liu Immunology 137 (1), 65-79, 2012 | 76 | 2012 |
The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy G Zhu, Q Zhang, EC Reddy, N Carrim, Y Chen, XR Xu, M Xu, Y Wang, ... Blood, The Journal of the American Society of Hematology 129 (13), 1840-1854, 2017 | 70 | 2017 |
Tracking neutrophil intraluminal crawling, transendothelial migration and chemotaxis in tissue by intravital video microscopy N Xu, X Lei, L Liu JoVE (Journal of Visualized Experiments), e3296, 2011 | 37 | 2011 |
In vitro assessment and phase I randomized clinical trial of anfibatide a snake venom derived anti-thrombotic agent targeting human platelet GPIbα BX Li, X Dai, XR Xu, R Adili, MAD Neves, X Lei, C Shen, G Zhu, Y Wang, ... Scientific reports 11 (1), 11663, 2021 | 33 | 2021 |
Endothelial-specific deletion of autophagy-related 7 (ATG7) attenuates arterial thrombosis in mice JW Yau, KK Singh, Y Hou, X Lei, A Ramadan, A Quan, H Teoh, ... The Journal of Thoracic and Cardiovascular Surgery 154 (3), 978-988. e1, 2017 | 32 | 2017 |
Different microvascular permeability responses elicited by the CXC chemokines MIP-2 and KC during leukocyte recruitment: role of LSP1 X Lei, M Hossain, SM Qadri, L Liu Biochemical and biophysical research communications 423 (3), 484-489, 2012 | 28 | 2012 |
Novel contact–kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke Z Zhang, C Shen, M Fang, Y Han, C Long, W Liu, M Yang, M Liu, D Zhang, ... Cellular and Molecular Life Sciences 79 (5), 240, 2022 | 18 | 2022 |
The first in vitro and in vivo assessment of anfibatide, a novel glycoprotein Ib antagonist, in mice and in a phase I human clinical trial Y Hou, X Lei, BX Li, X Dai, Z Yang, F Qian, G Zhang, Z Xu, J Liu, C Liang, ... Blood 122 (21), 577, 2013 | 14 | 2013 |
The fibrinogen but not the F actor VIII content of transfused plasma determines its effectiveness at reducing bleeding in coagulopathic mice LJ Eltringham‐Smith, X Lei, A Reheman, MD Lambourne, EL Pryzdial, ... Transfusion 55 (5), 1040-1050, 2015 | 11 | 2015 |
SARS-CoV-2 RBD and its variants can induce platelet activation and clearance: Implications for antibody therapy and vaccinations against COVID-19 X Ma, J Liang, G Zhu, P Bhoria, AA Shoara, DT MacKeigan, CJ Khoury, ... Research 6, 0124, 2023 | 8 | 2023 |
Control of data variations in intravital microscopy thrombosis models X Lei, DT MacKeigan, H Ni Journal of Thrombosis and Haemostasis 18 (11), 2823-2825, 2020 | 6 | 2020 |
Dual roles of fucoidan-GPIbα interaction in thrombosis and hemostasis: implications for drug development targeting GPIbα C Shen, DT Mackeigan, AA Shoara, R Xu, P Bhoria, D Karakas, W Ma, ... Journal of Thrombosis and Haemostasis 21 (5), 1274-1288, 2023 | 4 | 2023 |
Apolipoprotein Α-IV is a novel ligand of platelet αIIbβ3 integrin and an endogenous thrombosis inhibitor: measurement of single-molecular interactions by biomembrane force probe X Xu, CM Spring, L Ju, Y Wang, A Reheman, H Yang, JW Jin, X Lei, ... Blood 124 (21), 92, 2014 | 3 | 2014 |
Development of a novel antithrombotic therapy targeting platelet GPIbα: assessment of anfibatide in vitro and in phase I clinical trial Y Hou, A Reheman, BX Li, X Dai, Z Yang, F Qian, G Zhang, Z Xu, J Liu, ... Arteriosclerosis, Thrombosis, and Vascular Biology 34 (suppl_1), A499-A499, 2014 | 3 | 2014 |
Integrin PSI domain has endogenous thiol isomerase function and is a novel target for anti-thrombotic therapy N Carrim, G Zhu, EC Reddy, M Xu, X Xu, Y Wang, Y Hou, L Ma, C Lavalle, ... JOURNAL OF THROMBOSIS AND HAEMOSTASIS 13, 60-61, 2015 | 2 | 2015 |
Two Birds One Stone: Salvianolic Acid B Inhibits Coagulation And Platelet Aggregation M Neves, Y Wang, T Ni, X Lei, TW Stratton, S Yu, RC Gallant, D Zhang, ... Circulation 140 (Suppl_1), A17159-A17159, 2019 | 1 | 2019 |